2. Gene
  3. CEP70 - centrosomal protein 70 Gene

CEP70 - centrosomal protein 70 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：中心体蛋白 70

种属: Homo sapiens

同用名: BITE

基因 ID: 80321 | 基因类型: protein coding

关于 CEP70

Cytogenetic location: 3q22.3 Genomic coordinates (GRCh38): 3:138,494,344-138,594,260 (from NCBI)

This gene has 13 transcripts (splice variants) and 197 orthologues. Broad expression in testis (RPKM 11.4), duodenum (RPKM 7.8) and 22 other tissues.

功能概要

实现相同的蛋白质结合活性。预计参与纤毛组装和微管细胞骨架组织的调节。位于中心体。 [由基因组资源联盟提供，2022 年 4 月]

Enables identical protein binding activity. Predicted to be involved in cilium assembly and regulation of microtubule Cytoskeleton organization. Located in centrosome. [provided by Alliance of Genome Resources, Apr 2022]

CEP70 基因产物(8)

mRNA Protein Name
NM_001288964.2 NP_001275893.1 centrosomal protein of 70 kDa isoform 2
NM_001288965.2 NP_001275894.1 centrosomal protein of 70 kDa isoform 3
NM_001288966.2 NP_001275895.1 centrosomal protein of 70 kDa isoform 4
NM_001288967.2 NP_001275896.1 centrosomal protein of 70 kDa isoform 5
NM_001320598.2 NP_001307527.1 centrosomal protein of 70 kDa isoform 1
NM_001320599.2 NP_001307528.1 centrosomal protein of 70 kDa isoform 6
NM_001320600.1 NP_001307529.1 centrosomal protein of 70 kDa isoform 7
NM_024491.4 NP_077817.2 centrosomal protein of 70 kDa isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in centrosome IDA
IDA: 通过直接分析推断
21399614 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

centrosomal protein of 70 kDa

centrosomal protein 70kDa

关联疾病

疾病名称 别名
Refractory Plasma Cell Neoplasm
Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Refractory Hematologic Cancer

Refractory Hematologic Malignancy
Leukemia, Acute Lymphoblastic

Acute Lymphoblastic Leukemia

ALL

Acute Lymphocytic Leukemia

Leukemia, Acute Lymphocytic, Susceptibility To, 1

Acute Lymphoblastic Leukaemia

Precursor Lymphoblastic Lymphoma/Leukemia

Precursor Lymphoid Neoplasm

Leukemia, Acute Lymphoblastic, Susceptibility To

B-Cell Acute Lymphoblastic Leukemia

Leukemia, Acute Lymphocytic 1

Acute Lymphocytic Leukaemia

Acute Lymphoblastic Leukemia/Lymphoma

All1

Childhood Acute Lymphoblastic Leukemia

Leukemia Acute Lymphoblastic 1

Leukemia Acute Lymphoblastic B-Hyperdiploid

Leukemia Acute Lymphocytic

Leukemia Acute Lymphocytic 1

Leukemia B-Cell Acute Lymphoblastic

Leukemia T-Cell Acute Lymphoblastic

Leukemia, Acute Lymphoblastic, 3

ALL3

Lymphoblastic Leukemia Acute

Leukemia, Acute, Lymphoblastic

Precursor Cell Lymphoblastic Leukemia Lymphoma

Leukemia, Lymphocytic, Acute, L1

Leukemia, Acute Lymphoblastic, Susceptibility To, 3
Leukemia, Acute Myeloid

Acute Myeloid Leukemia

Leukemia, Acute Myelogenous

Acute Myelogenous Leukemia

AML

Leukemia, Acute Myeloid, Susceptibility To

Acute Myeloblastic Leukemia

Leukemia, Acute Myeloid, Reduced Survival In, Somatic

Acute Myeloid Leukaemia

Leukemia, Myelocytic, Acute

Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome

Secondary Aml

Acute Myelocytic Leukemia

Acute Myeloid Leukemia, Somatic

Leukemia, Acute Myeloid, Somatic

Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic

Acute Myeloblastic Leukaemia

Acute Myelogenous Leukaemia

Aml - Acute Myeloid Leukemia

Acute Myeloid Leukemia With Cebpa Somatic Mutations

Aml With Cebpa Somatic Mutations

Inherited Acute Myeloid Leukemia

Familial Aml

Inherited Aml

Pure Familial Aml

Pure Familial Acute Myeloid Leukemia

Secondary Acute Myeloid Leukemia

Therapy-Related Aml And Myelodysplastic Syndrome

Acute Myeloid Leukemia, Secondary

Acute Non-Lymphoblastic Leukemia

Acute Non-Lymphocytic Leukemia

Acute Biphenotypic Leukemia

Acute Undifferentiated Leukemia

Acute Myeloblastic Leukaemia With Multilineage Dysplasia

Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission

Acute Myeloid Leukaemia With Myelodysplasia-Related Features
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02521 CEP70 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus CEP70 VGNC VGNC:60781
Canis familiaris CEP70 VGNC VGNC:39135
Rattus norvegicus CEP70 RGD RGD:1561486
Mus musculus CEP70 MGD MGI:1915371
Bos taurus CEP70 VGNC VGNC:27211
Macaca mulatta CEP70 VGNC VGNC:71140
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