PIMREG - PICALM interacting mitotic regulator Gene

中文名称：PICALM 相互作用的有丝分裂调节因子

种属: Homo sapiens

同用名: CATS; RCS1; FAM64A

基因 ID: 54478 | 基因类型: protein coding

关于 PIMREG

Cytogenetic location: 17p13.2 Genomic coordinates (GRCh38): 17:6,444,455-6,451,469 (from NCBI)

This gene has 9 transcripts (splice variants) and 164 orthologues. Broad expression in spleen (RPKM 1.3), small intestine (RPKM 0.7) and 19 other tissues.

功能概要

预测参与细胞分裂。位于核仁和核质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in cell division. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PIMREG 基因产物(2)

mRNA	Protein	Name
NM_001195228.2	NP_001182157.1	protein PIMREG isoform 2
NM_019013.3	NP_061886.2	protein PIMREG isoform 1

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	18482256	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PIMREG 蛋白结构

DUF1466

0
100
200
248 a.a.

蛋白主名

其他名称

protein PIMREG

CALM interacting protein expressed in thymus and spleen

PIMREG 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	PIMREG	Q9BSJ6	KRT40	Homo sapiens	Q6A162	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	KRT40	Homo sapiens	Q6A162	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	KRT40	Homo sapiens	Q6A162	Y2H Array	25416956
Intra	PIMREG	Q9BSJ6	KRT40	Homo sapiens	Q6A162	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	HOOK2	Homo sapiens	Q96ED9-2	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	HOOK2	Homo sapiens	Q96ED9-2	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	HOOK2	Homo sapiens	Q96ED9-2	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	AGTRAP	Homo sapiens	Q6RW13-2	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	AGTRAP	Homo sapiens	Q6RW13-2	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	AGTRAP	Homo sapiens	Q6RW13-2	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	CMTM5	Homo sapiens	Q96DZ9-2	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	CMTM5	Homo sapiens	Q96DZ9-2	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	CMTM5	Homo sapiens	Q96DZ9-2	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	SIAH1	Homo sapiens	Q8IUQ4-2	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	SIAH1	Homo sapiens	Q8IUQ4-2	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	SIAH1	Homo sapiens	Q8IUQ4-2	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	SSX2IP	Homo sapiens	Q9Y2D8	Validated Y2H	25416956
Intra	PIMREG	Q9BSJ6	SSX2IP	Homo sapiens	Q9Y2D8	Y2H Array	25416956
Intra	PIMREG	Q9BSJ6	DOCK8	Homo sapiens	Q8NF50	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	DOCK8	Homo sapiens	Q8NF50	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	DOCK8	Homo sapiens	Q8NF50	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	VPS52	Homo sapiens	Q8N1B4	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	VPS52	Homo sapiens	Q8N1B4	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	VPS52	Homo sapiens	Q8N1B4	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	SPAG5	Homo sapiens	Q96R06	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	SPAG5	Homo sapiens	Q96R06	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	SPAG5	Homo sapiens	Q96R06	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	GOLGA2	Homo sapiens	Q08379	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	GOLGA2	Homo sapiens	Q08379	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	TFCP2	Homo sapiens	Q12800	Validated Y2H	25416956
Intra	PIMREG	Q9BSJ6	TFCP2	Homo sapiens	Q12800	Y2H Array	25416956
Intra	PIMREG	Q9BSJ6	TRIM27	Homo sapiens	P14373	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	TRIM27	Homo sapiens	P14373	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	TRIM27	Homo sapiens	P14373	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	BEND5	Homo sapiens	Q7L4P6	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	BEND5	Homo sapiens	Q7L4P6	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	BEND5	Homo sapiens	Q7L4P6	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	RINT1	Homo sapiens	Q6NUQ1	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	RINT1	Homo sapiens	Q6NUQ1	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	RINT1	Homo sapiens	Q6NUQ1	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	CEP70	Homo sapiens	Q8NHQ1	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	CEP70	Homo sapiens	Q8NHQ1	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	CEP70	Homo sapiens	Q8NHQ1	Y2H Prey Pooling	25416956
Intra	PIMREG	Q9BSJ6	CEP70	Homo sapiens	Q8NHQ1	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	AGTRAP	Homo sapiens	Q6RW13	Validated Y2H	25416956
Intra	PIMREG	Q9BSJ6	ARMC7	Homo sapiens	Q9H6L4	Validated Y2H	32296183
Intra	PIMREG	Q9BSJ6	CCNDBP1	Homo sapiens	O95273	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	CCNDBP1	Homo sapiens	O95273	Validated Y2H	25416956
Intra	PIMREG	Q9BSJ6	CCNDBP1	Homo sapiens	O95273	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	CCNDBP1	Homo sapiens	O95273	Y2H Prey Pooling	25416956
Intra	PIMREG	Q9BSJ6	CCNDBP1	Homo sapiens	O95273	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	CCNDBP1	Homo sapiens	O95273	Y2H Array	25416956
Intra	PIMREG	Q9BSJ6	MAL2	Homo sapiens	Q969L2	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	MAL2	Homo sapiens	Q969L2	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	MAL2	Homo sapiens	Q969L2	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	PRNP	Homo sapiens	P04156	Protein Array	18482256

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Suppurative Periapical Periodontitis

Periapical Abscess	Apical Abscess
Suppurative Apical Periodontitis	Dentoalveolar Abscess
Dental Abscess With Sinus	Dentoalveolar Abscess With Sinus
Dental Sinus	Periapical Abscess Fistula
Apical Tooth Abscess	Apex Abscess
Dental Abscess Nos	Infection Of Tooth Nos
Abscess Of Tooth	Dental Infection Nos

Paragonimiasis

Infection By Paragonimus	Lung Fluke Disease
Lung Fluke Infection	Pulmonary Paragonimiasis
Paragonimus Westermani Infection	Pulmonary Distomiasis
Parasitic Haemoptysis	Oriental Lung Fluke Disease
Endemic Haemoptysis	Paragonimosis
Pulmonary Distomatosis	Lung Fluke Disorder
Infestation By Paragonimus	Infection Due To Paragonimus Species
Infestation Due To Paragonimus Species	Oriental Lung Fluke Infestation
Endemic Oriental Haemoptysis

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS10556	PIMREG Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	PIMREG	VGNC	VGNC:64179
Rattus norvegicus	PIMREG	RGD	RGD:1308747
Macaca mulatta	PIMREG	VGNC	VGNC:99195
Canis familiaris	PIMREG	VGNC	VGNC:44566
Bos taurus	PIMREG	VGNC	VGNC:32902
Mus musculus	PIMREG	MGD	MGI:1924434

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