2. Gene
  3. METTL17 - methyltransferase like 17 Gene

METTL17 - methyltransferase like 17 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：甲基转移酶样 17

种属: Homo sapiens

同用名: METT11D1

基因 ID: 64745 | 基因类型: protein coding

关于 METTL17

Cytogenetic location: 14q11.2 Genomic coordinates (GRCh38): 14:20,989,980-20,997,035 (from NCBI)

This gene has 25 transcripts (splice variants), 180 orthologues and 1 paralogue. Ubiquitous expression in duodenum (RPKM 22.3), lymph node (RPKM 19.6) and 25 other tissues.

功能概要

预计具有 S-腺苷-L-甲硫氨酸结合活性和线粒体核糖体结合活性。预测参与核糖体小亚基生物合成。位于核质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable S-adenosyl-L-methionine binding activity and mitochondrial ribosome binding activity. Predicted to be involved in ribosomal small subunit biogenesis. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

METTL17 基因产物(2)

mRNA Protein Name
NM_001029991.2 NP_001025162.1 methyltransferase-like protein 17, mitochondrial isoform 1 precursor
NM_022734.3 NP_073571.1 methyltransferase-like protein 17, mitochondrial isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 4 iron, 4 sulfur cluster binding IDA
IDA: 通过直接分析推断
36482135 GOA
NOT enables methyltransferase activity IDA
IDA: 通过直接分析推断
38234605 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in mitochondrial small ribosomal subunit assembly IDA
IDA: 通过直接分析推断
36482135 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

METTL17 蛋白结构

Rsm22

Rsm22: Mitochondrial small ribosomal subunit Rsm22 (155 - 438)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 456 a.a.
蛋白主名 其他名称

methyltransferase-like protein 17, mitochondrial

false p73 target gene protein

METTL17 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra METTL17 Q9H7H0 KRT40 Homo sapiens Q6A162
Y2H Array
25416956
Intra METTL17 Q9H7H0 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
26871637
Intra METTL17 Q9H7H0 MID2 Homo sapiens Q9UJV3-2
Y2H Array
26871637
Intra METTL17 Q9H7H0 MID2 Homo sapiens Q9UJV3-2
Y2H Prey Pooling
26871637
Intra METTL17 Q9H7H0 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
25416956
Intra METTL17 Q9H7H0 TFIP11 Homo sapiens Q9UBB9
Y2H Array
25416956
Intra METTL17 Q9H7H0 PNMA1 Homo sapiens Q8ND90
Y2H Prey Pooling
26871637
Intra METTL17 Q9H7H0 PNMA1 Homo sapiens Q8ND90
Validated Y2H
26871637
Intra METTL17 Q9H7H0 PNMA1 Homo sapiens Q8ND90
Y2H Prey Pooling
25416956
Intra METTL17 Q9H7H0 PNMA1 Homo sapiens Q8ND90
Y2H Array
26871637
Intra METTL17 Q9H7H0 SF3B4 Homo sapiens Q15427
Y2H Array
25416956
Intra METTL17 Q9H7H0 TRAF1 Homo sapiens Q13077
Validated Y2H
26871637
Intra METTL17 Q9H7H0 TRAF1 Homo sapiens Q13077
Y2H Prey Pooling
26871637
Intra METTL17 Q9H7H0 TRAF1 Homo sapiens Q13077
Y2H Array
26871637
Intra METTL17 Q9H7H0 TRAF1 Homo sapiens Q13077
Y2H Prey Pooling
25416956
Intra METTL17 Q9H7H0 MDFI Homo sapiens Q99750
Y2H Prey Pooling
26871637
Intra METTL17 Q9H7H0 MDFI Homo sapiens Q99750
Validated Y2H
26871637
Intra METTL17 Q9H7H0 MDFI Homo sapiens Q99750
Y2H Array
26871637
Intra METTL17 Q9H7H0 CALCOCO2 Homo sapiens Q13137
Validated Y2H
25416956
Intra METTL17 Q9H7H0 CALCOCO2 Homo sapiens Q13137
Validated Y2H
26871637
Intra METTL17 Q9H7H0 CALCOCO2 Homo sapiens Q13137
Y2H Array
26871637
Intra METTL17 Q9H7H0 CALCOCO2 Homo sapiens Q13137
Y2H Prey Pooling
25416956
Intra METTL17 Q9H7H0 CALCOCO2 Homo sapiens Q13137
Y2H Prey Pooling
26871637
Intra METTL17 Q9H7H0 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
26871637
Intra METTL17 Q9H7H0 CEP70 Homo sapiens Q8NHQ1
Validated Y2H
26871637
Intra METTL17 Q9H7H0 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
25416956
Intra METTL17 Q9H7H0 CEP70 Homo sapiens Q8NHQ1
Y2H Array
26871637
Intra METTL17 Q9H7H0 CBY2 Homo sapiens Q8NA61
Y2H Array
25416956
Intra METTL17 Q9H7H0 CBY2 Homo sapiens Q8NA61
Validated Y2H
25416956
Intra METTL17 Q9H7H0 ATXN1 Homo sapiens P54253
Y2H Array
16713569
Intra METTL17 Q9H7H0 ATXN1 Homo sapiens P54253
Y2H
16713569
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08358 METTL17 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus METTL17 MGD MGI:1098577
Canis familiaris METTL17 VGNC VGNC:106604
Macaca mulatta METTL17 VGNC VGNC:81473
Felis catus METTL17 VGNC VGNC:80913
Bos taurus METTL17 VGNC VGNC:55124
Rattus norvegicus METTL17 RGD RGD:1559895
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