2. Gene
  3. TRAF3IP3 - TRAF3 interacting protein 3 Gene

TRAF3IP3 - TRAF3 interacting protein 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：TRAF3 相互作用蛋白 3

种属: Homo sapiens

同用名: T3JAM

基因 ID: 80342 | 基因类型: protein coding

关于 TRAF3IP3

Cytogenetic location: 1q32.2 Genomic coordinates (GRCh38): 1:209,756,053-209,782,310 (from NCBI)

This gene has 16 transcripts (splice variants), 189 orthologues and 2 paralogues. Biased expression in lymph node (RPKM 18.7), spleen (RPKM 13.0) and 9 other tissues.

功能概要

该基因编码一种蛋白质，该蛋白质通过调节 c-Jun N 末端激酶信号转导途径来介导细胞生长。编码的蛋白质还可以与含有磷酸酶 2A 催化亚基的大型多蛋白组装体相互作用。可变剪接导致多个转录本变体。[RefSeq 提供，2013 年 12 月]

The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multi-protein assembly containing the Phosphatase 2A catalytic subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

TRAF3IP3 基因产物(4)

mRNA Protein Name
NM_001287754.2 NP_001274683.1 TRAF3-interacting JNK-activating modulator isoform 2
NM_001320143.2 NP_001307072.1 TRAF3-interacting JNK-activating modulator isoform 1
NM_001320144.2 NP_001307073.1 TRAF3-interacting JNK-activating modulator isoform 4
NM_025228.4 NP_079504.2 TRAF3-interacting JNK-activating modulator isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables molecular adaptor activity IDA
IDA: 通过直接分析推断
31390091 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
18782753 GOA
enables protein-macromolecule adaptor activity IDA
IDA: 通过直接分析推断
31390091 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cytoplasmic pattern recognition receptor signaling pathway IDA
IDA: 通过直接分析推断
31390091 GOA
involved in positive regulation of type I interferon production IDA
IDA: 通过直接分析推断
31390091 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in mitochondrion IDA
IDA: 通过直接分析推断
31390091 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

TRAF3-interacting JNK-activating modulator

TRAF3 interacting Jun N terminal kinase (JNK) activating modulator

TRAF3IP3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra TRAF3IP3 Q9Y228 STRN Homo sapiens O43815
Anti Tag CoIP
33961781
Intra TRAF3IP3 Q9Y228 STRN Homo sapiens O43815
Anti Tag CoIP
18782753
Intra TRAF3IP3 Q9Y228 OSBPL3 Homo sapiens Q9H4L5
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 OSBPL3 Homo sapiens Q9H4L5
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 STRN3 Homo sapiens Q13033
Anti Tag CoIP
33961781
Intra TRAF3IP3 Q9Y228 STRN3 Homo sapiens Q13033
Anti Tag CoIP
18782753
Intra TRAF3IP3 Q9Y228 CCDC138 Homo sapiens Q96M89-2
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 CCDC138 Homo sapiens Q96M89-2
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 TFIP11 Homo sapiens Q9UBB9
Y2H Array
31515488
Intra TRAF3IP3 Q9Y228 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
25416956
Intra TRAF3IP3 Q9Y228 TFIP11 Homo sapiens Q9UBB9
Y2H Array
25416956
Intra TRAF3IP3 Q9Y228 LRRC25 Homo sapiens Q8N386
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 LRRC25 Homo sapiens Q8N386
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 MFF Homo sapiens Q9GZY8-5
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 MFF Homo sapiens Q9GZY8-5
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 CEP68 Homo sapiens Q76N32-2
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 CEP68 Homo sapiens Q76N32-2
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 MINAR1 Homo sapiens Q9UPX6
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 MINAR1 Homo sapiens Q9UPX6
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 GRAMD2A Homo sapiens Q8IUY3
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 GRAMD2A Homo sapiens Q8IUY3
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 L3MBTL3 Homo sapiens Q96JM7-2
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 L3MBTL3 Homo sapiens Q96JM7-2
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 RILPL1 Homo sapiens Q5EBL4-3
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 RILPL1 Homo sapiens Q5EBL4-3
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 RIC3 Homo sapiens Q7Z5B4-5
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 RIC3 Homo sapiens Q7Z5B4-5
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 EVI2B Homo sapiens P34910-2
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 EVI2B Homo sapiens P34910-2
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 STRIP1 Homo sapiens Q5VSL9
Anti Tag CoIP
18782753
Intra TRAF3IP3 Q9Y228 STRIP1 Homo sapiens Q5VSL9
Anti Tag CoIP
33961781
Intra TRAF3IP3 Q9Y228 SIKE1 Homo sapiens Q9BRV8
Anti Tag CoIP
18782753
Intra TRAF3IP3 Q9Y228 SIKE1 Homo sapiens Q9BRV8
Anti Tag CoIP
33961781
Intra TRAF3IP3 Q9Y228 CPLX4 Homo sapiens Q7Z7G2
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 CPLX4 Homo sapiens Q7Z7G2
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 CBARP Homo sapiens Q8N350-4
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 CBARP Homo sapiens Q8N350-4
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 STMN4 Homo sapiens Q9H169-2
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 STMN4 Homo sapiens Q9H169-2
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 LIME1 Homo sapiens Q9H400
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 LIME1 Homo sapiens Q9H400
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 TGFBR2 Homo sapiens P37173
Validated Y2H
32814053
Intra TRAF3IP3 Q9Y228 TGFBR2 Homo sapiens P37173
Y2H Array
32814053
Intra TRAF3IP3 Q9Y228 TGFBR2 Homo sapiens P37173
Y2H Pooling
32814053
Intra TRAF3IP3 Q9Y228 KRT27 Homo sapiens Q7Z3Y8
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 KRT27 Homo sapiens Q7Z3Y8
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 CCDC88B Homo sapiens A6NC98
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 CCDC88B Homo sapiens A6NC98
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 GORAB Homo sapiens Q5T7V8
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 GORAB Homo sapiens Q5T7V8
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 CCNC Homo sapiens P24863
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 CCNC Homo sapiens P24863
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 PRKACA Homo sapiens P17612
Y2H Array
32814053
Intra TRAF3IP3 Q9Y228 PRKACA Homo sapiens P17612
Y2H Pooling
32814053
Intra TRAF3IP3 Q9Y228 PRKACA Homo sapiens P17612
Validated Y2H
32814053
Intra TRAF3IP3 Q9Y228 EMD Homo sapiens P50402
Validated Y2H
32296183
Intra TRAF3IP3 Q9Y228 ZRANB1 Homo sapiens Q9UGI0
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 ZRANB1 Homo sapiens Q9UGI0
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 CDCA7L Homo sapiens Q96GN5
Y2H Prey Pooling
25416956
Intra TRAF3IP3 Q9Y228 CDCA7L Homo sapiens Q96GN5
Y2H Array
25416956
Intra TRAF3IP3 Q9Y228 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 SP100 Homo sapiens P23497-2
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 SP100 Homo sapiens P23497-2
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 STX1A Homo sapiens Q16623
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 STX1A Homo sapiens Q16623
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 MOB4 Homo sapiens Q9Y3A3
Anti Tag CoIP
33961781
Intra TRAF3IP3 Q9Y228 MOB4 Homo sapiens Q9Y3A3
Anti Tag CoIP
18782753
Intra TRAF3IP3 Q9Y228 RACGAP1 Homo sapiens Q9H0H5
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 RACGAP1 Homo sapiens Q9H0H5
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 TMEM139 Homo sapiens Q8IV31
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 TMEM139 Homo sapiens Q8IV31
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 COQ9 Homo sapiens O75208
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 COQ9 Homo sapiens O75208
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 CEP70 Homo sapiens Q8NHQ1
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 STK24 Homo sapiens Q9Y6E0
Anti Tag CoIP
18782753
Intra TRAF3IP3 Q9Y228 ZNRD2 Homo sapiens O60232
Y2H Prey Pooling
25416956
Intra TRAF3IP3 Q9Y228 ZNRD2 Homo sapiens O60232
Y2H Array
25416956
Intra TRAF3IP3 Q9Y228 FATE1 Homo sapiens Q969F0
Validated Y2H
25416956
Intra TRAF3IP3 Q9Y228 FATE1 Homo sapiens Q969F0
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 FATE1 Homo sapiens Q969F0
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 STX4 Homo sapiens Q12846
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 STX4 Homo sapiens Q12846
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 RAD23A Homo sapiens P54725
Validated Y2H
32814053
Intra TRAF3IP3 Q9Y228 RAD23A Homo sapiens P54725
Y2H Array
32814053
Intra TRAF3IP3 Q9Y228 RAD23A Homo sapiens P54725
Y2H Pooling
32814053
Intra TRAF3IP3 Q9Y228 WAC Homo sapiens Q9BTA9
Y2H Array
25416956
Intra TRAF3IP3 Q9Y228 KASH5 Homo sapiens Q8N6L0
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 KASH5 Homo sapiens Q8N6L0
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 SP100 Homo sapiens P23497
Y2H Array
31515488
Intra TRAF3IP3 Q9Y228 SP100 Homo sapiens P23497
Y2H Prey Pooling
25416956
Intra TRAF3IP3 Q9Y228 CREB3L3 Homo sapiens Q68CJ9
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 CREB3L3 Homo sapiens Q68CJ9
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 KIR2DL3 Homo sapiens P43628
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 KIR2DL3 Homo sapiens P43628
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 EBAG9 Homo sapiens O00559
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 EBAG9 Homo sapiens O00559
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 NDEL1 Homo sapiens Q9GZM8
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 NDEL1 Homo sapiens Q9GZM8
Y2H Prey Pooling
25416956
Intra TRAF3IP3 Q9Y228 NDEL1 Homo sapiens Q9GZM8
Y2H Prey Pooling
32296183
Intra TRAF3IP3 Q9Y228 PLEKHO1 Homo sapiens Q53GL0
Y2H Array
32296183
Intra TRAF3IP3 Q9Y228 PLEKHO1 Homo sapiens Q53GL0
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14972 TRAF3IP3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus TRAF3IP3 VGNC VGNC:36275
Mus musculus TRAF3IP3 MGD MGI:2441706
Rattus norvegicus TRAF3IP3 RGD RGD:1304848
Felis catus TRAF3IP3 VGNC VGNC:66499
Canis familiaris TRAF3IP3 VGNC VGNC:47767
Macaca mulatta TRAF3IP3 VGNC VGNC:79877
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z