2. Gene
  3. STRIP1 - striatin interacting protein 1 Gene

STRIP1 - striatin interacting protein 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：纹状蛋白相互作用蛋白 1

种属: Homo sapiens

同用名: FAM40A; FAR11A

基因 ID: 85369 | 基因类型: protein coding

关于 STRIP1

Cytogenetic location: 1p13.3 Genomic coordinates (GRCh38): 1:110,031,577-110,054,641 (from NCBI)

This gene has 9 transcripts (splice variants), 209 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 12.7), bone marrow (RPKM 10.4) and 25 other tissues.

功能概要

该基因编码与纹状蛋白相互作用的磷酸酶和激酶复合物的成员，该复合物参与高尔基体的定位。编码的蛋白质参与细胞骨架组织。可变剪接导致多个转录本变体。[RefSeq 提供，2012 年 7 月]

This gene encodes a member of the striatin-interacting Phosphatase and kinase complex, which is involved in localization of the Golgi body. The encoded protein participates in cytosketelal organization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

STRIP1 基因产物(2)

mRNA Protein Name
NM_001270768.2 NP_001257697.1 striatin-interacting protein 1 isoform 2
NM_033088.4 NP_149079.2 striatin-interacting protein 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18782753 GOA
enables protein-macromolecule adaptor activity IDA
IDA: 通过直接分析推断
30622739 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cortical actin cytoskeleton organization IMP
IMP: 通过突变表型推断
21834987 GOA
involved in negative regulation of hippo signaling IDA
IDA: 通过直接分析推断
30622739 GOA
involved in regulation of cell morphogenesis IMP
IMP: 通过突变表型推断
21834987 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of FAR/SIN/STRIPAK complex IDA
IDA: 通过直接分析推断
18782753 GOA
located in nucleus IDA
IDA: 通过直接分析推断
15302935 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

STRIP1 蛋白结构

N1221

N1221: N1221-like protein (66 - 347)

DUF3402

DUF3402: Domain of unknown function (DUF3402) (420 - 808)

  • 0
  • 200
  • 400
  • 600
  • 837 a.a.
蛋白主名 其他名称

striatin-interacting protein 1

FAR11 factor arrest 11 homolog A

STRIP1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
STRIP1 Q5VSL9 PPP2CB Homo sapiens P62714
Anti Tag CoIP
33961781
种属内
STRIP1 Q5VSL9 PPP2CB Homo sapiens P62714
Anti Tag CoIP
25531779
种属内
STRIP1 Q5VSL9 PPP2CB Homo sapiens P62714
Anti Tag CoIP
18782753
种属内
STRIP1 Q5VSL9 CTTNBP2NL Homo sapiens Q9P2B4
Anti Tag CoIP
18782753
种属内
STRIP1 Q5VSL9 CTTNBP2NL Homo sapiens Q9P2B4
Anti Tag CoIP
33961781
种属内
STRIP1 Q5VSL9 STK26 Homo sapiens Q9P289
Anti Tag CoIP
18782753
种属内
STRIP1 Q5VSL9 PPP2CA Homo sapiens P67775
Anti Tag CoIP
18782753
种属内
STRIP1 Q5VSL9 PPP2CA Homo sapiens P67775
Anti Tag CoIP
33961781
种属内
STRIP1 Q5VSL9 PPP2CA Homo sapiens P67775
Anti Tag CoIP
25531779
种属内
STRIP1 Q5VSL9 STK24 Homo sapiens Q9Y6E0
Anti Tag CoIP
25531779
种属内
STRIP1 Q5VSL9 STK24 Homo sapiens Q9Y6E0
Anti Tag CoIP
18782753
种属内
STRIP1 Q5VSL9 TRAF3IP3 Homo sapiens Q9Y228
Anti Tag CoIP
18782753
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Cerebral Cavernous Malformations 3

Cerebral Cavernous Malformation 3

CCM3

Cerebral Cavernous Malformations-3

Cavernous Angiomatous Malformations

Cavernous Hemangioma Of The Brain

Cerebral Capillary Malformations

Cerebral Cavernoma

Familial Cavernous Angioma

Cerebral Cavernous Malformations, Type 3
Root Caries

Cementum Caries

Dental Caries Of Root Surface
Cerebral Cavernous Malformations

Cerebral Cavernous Malformation

Cavernous Malformations Of Cns And Retina

Cerebral Cavernous Malformation 1

Cavernous Angiomatous Malformations

Cerebral Capillary Malformations

CCM

Hyperkeratotic Cutaneous Capillary-Venous Malformations Associated With Cerebral Capillary Malformations

Familial Cavernous Angioma

Cavernous Angioma

Familial Cerebral Cavernous Malformation

Cerebral Cavernous Malformations 1

Cavernous Angioma, Familial

Cam

Cerebral Cavernous Malformations-1

Cavernoma

Central Nervous System Cavernous Hemangioma

Cerebral Cavernous Hemangioma

Familial Cavernous Hemangioma

Familial Cavernous Malformation

Familial Cerebral Cavernous Angioma

Intracerebral Cavernous Hemangioma

CCM1

Cavernous Hemangioma Of The Brain

Cerebral Cavernoma

Cerebral Cavernous Malformations, Type 1

Hemangioma, Cavernous, Central Nervous System

Hemangioma, Cavernous

Angioma, Cavernous
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N10881 Dihydrocurcumenone / 否
HY-RS13964 STRIP1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus STRIP1 MGD MGI:2443884
Canis familiaris STRIP1 VGNC VGNC:46943
Rattus norvegicus STRIP1 RGD RGD:1564249
Macaca mulatta STRIP1 VGNC VGNC:78217
Bos taurus STRIP1 VGNC VGNC:35422
Felis catus STRIP1 VGNC VGNC:65801
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