1. Gene
  2. CARD9 - caspase recruitment domain family member 9 Gene

CARD9 - caspase recruitment domain family member 9 Gene

中文名称:胱天蛋白酶招募域家族成员 9

种属: Homo sapiens

同用名: CANDF2; IMD103; hCARD9

基因 ID: 64170 | 基因类型: protein coding

关于 CARD9

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:136,363,956-136,373,669 (from NCBI)

This gene has 11 transcripts (splice variants), 188 orthologues, 3 paralogues and is associated with 2 phenotypes. Broad expression in bone marrow (RPKM 5.8), spleen (RPKM 4.7) and 19 other tissues.

功能概要

由该基因编码的蛋白质是 CARD 蛋白质家族的成员,该家族由特征性半胱天冬酶相关募集域 (CARD) 的存在定义。 CARD 是已知参与激活或抑制含有 Caspase 家族成员的 CARD 的蛋白质相互作用结构域,因此在细胞凋亡中起着重要的调节作用。这种蛋白质是通过其与 BCL10 的 CARD 域的选择性关联而确定的,BCL10 是细胞凋亡和 NF-kappaB 激活的正调节因子,并且被认为可以作为组装 BCL10 信号复合物激活 NF-kappaB 的分子支架。已经观察到几种选择性剪接的转录物变体,但它们的全长性质没有明确定义。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the Caspase family, and thus plays an important regulatory role in cell Apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of Apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined. [provided by RefSeq, Jul 2008]

CARD9 基因产物(2)

mRNA Protein Name
NM_052813.5 NP_434700.2 caspase recruitment domain-containing protein 9 isoform 1
NM_052814.4 NP_434701.1 caspase recruitment domain-containing protein 9 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables CARD domain binding IPI
IPI: 通过物理相互作用推断
11053425 GOA
enables identical protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
22267217 GOA
enables protein homodimerization activity IPI
IPI: 通过物理相互作用推断
11053425 GOA
enables signaling adaptor activity IDA
IDA: 通过直接分析推断
11053425 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in antifungal innate immune response IDA
IDA: 通过直接分析推断
26488816 GOA
involved in antifungal innate immune response IMP
IMP: 通过突变表型推断
24231284 GOA
involved in host-mediated regulation of intestinal microbiota composition IMP
IMP: 通过突变表型推断
33548172 GOA
involved in immunoglobulin mediated immune response IMP
IMP: 通过突变表型推断
33548172 GOA
involved in neutrophil mediated immunity IMP
IMP: 通过突变表型推断
26679537 GOA
acts upstream of or within positive regulation of JNK cascade IDA
IDA: 通过直接分析推断
17187069 GOA
involved in positive regulation of NF-kappaB transcription factor activity IDA
IDA: 通过直接分析推断
26488816 GOA
involved in positive regulation of NF-kappaB transcription factor activity IMP
IMP: 通过突变表型推断
25057046 GOA
involved in positive regulation of T-helper 17 type immune response IMP
IMP: 通过突变表型推断
24231284 GOA
involved in positive regulation of canonical NF-kappaB signal transduction IDA
IDA: 通过直接分析推断
11053425 GOA
involved in positive regulation of canonical NF-kappaB signal transduction IEP
IEP: 通过表达模式推断
11053425 GOA
involved in positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
IMP: 通过突变表型推断
22267217 GOA
involved in positive regulation of cytokine production IMP
IMP: 通过突变表型推断
24231284 GOA
involved in positive regulation of granulocyte macrophage colony-stimulating factor production IMP
IMP: 通过突变表型推断
26961233 GOA
involved in positive regulation of interleukin-17 production IMP
IMP: 通过突变表型推断
26961233 GOA
involved in positive regulation of interleukin-6 production IMP
IMP: 通过突变表型推断
25702837 GOA
acts upstream of or within positive regulation of stress-activated MAPK cascade IDA
IDA: 通过直接分析推断
17187069 GOA
involved in protein homooligomerization IDA
IDA: 通过直接分析推断
31296852 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cytoplasm IDA
IDA: 通过直接分析推断
26488816 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
11053425 GOA
part of protein-containing complex IDA
IDA: 通过直接分析推断
22267217 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CARD9 蛋白结构

CARD

CARD: Caspase recruitment domain (11 - 96)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 536 a.a.
蛋白主名 其他名称

caspase recruitment domain-containing protein 9

CARD9 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra CARD9 Q9H257 PNMA5 Homo sapiens Q96PV4
Validated Y2H
25416956
Intra CARD9 Q9H257 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 KRTAP10-5 Homo sapiens P60370
Validated Y2H
25416956
Intra CARD9 Q9H257 KRTAP10-5 Homo sapiens P60370
Y2H Array
25416956
Intra CARD9 Q9H257 TASOR2 Homo sapiens Q5VWN6-2
Y2H Array
25416956
Intra CARD9 Q9H257 TASOR2 Homo sapiens Q5VWN6-2
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 ZNF572 Homo sapiens Q7Z3I7
Validated Y2H
25416956
Intra CARD9 Q9H257 ZNF572 Homo sapiens Q7Z3I7
Y2H Array
25416956
Intra CARD9 Q9H257 ZNF572 Homo sapiens Q7Z3I7
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 NECAB2 Homo sapiens Q7Z6G3-2
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 NECAB2 Homo sapiens Q7Z6G3-2
Y2H Array
25416956
Intra CARD9 Q9H257 a8k932_human Homo sapiens A8K932
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 a8k932_human Homo sapiens A8K932
Y2H Array
25416956
Intra CARD9 Q9H257 a8k932_human Homo sapiens A8K932
Validated Y2H
25416956
Intra CARD9 Q9H257 CCHCR1 Homo sapiens Q8TD31-3
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 CCHCR1 Homo sapiens Q8TD31-3
Validated Y2H
25416956
Intra CARD9 Q9H257 CCHCR1 Homo sapiens Q8TD31-3
Y2H Array
25416956
Intra CARD9 Q9H257 ZNF250 Homo sapiens P15622-3
Validated Y2H
25416956
Intra CARD9 Q9H257 CEP57L1 Homo sapiens Q8IYX8-2
Y2H Array
25416956
Intra CARD9 Q9H257 CEP57L1 Homo sapiens Q8IYX8-2
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 AMOTL2 Homo sapiens Q9Y2J4-4
Validated Y2H
25416956
Intra CARD9 Q9H257 AMOTL2 Homo sapiens Q9Y2J4-4
Y2H Array
25416956
Intra CARD9 Q9H257 RTP5 Homo sapiens Q14D33
Validated Y2H
25416956
Intra CARD9 Q9H257 RTP5 Homo sapiens Q14D33
Y2H Array
25416956
Intra CARD9 Q9H257 RTP5 Homo sapiens Q14D33
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 VPS28 Homo sapiens Q548N1
Validated Y2H
25416956
Intra CARD9 Q9H257 VPS28 Homo sapiens Q548N1
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 USP15 Homo sapiens Q9Y4E8
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 USP15 Homo sapiens Q9Y4E8
Y2H Array
25416956
Intra CARD9 Q9H257 TRIM54 Homo sapiens Q9BYV2
Y2H Array
25416956
Intra CARD9 Q9H257 TRIM54 Homo sapiens Q9BYV2
Validated Y2H
25416956
Intra CARD9 Q9H257 TRIM54 Homo sapiens Q9BYV2
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 TSNAX Homo sapiens Q99598
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 TSNAX Homo sapiens Q99598
Validated Y2H
25416956
Intra CARD9 Q9H257 SSX2IP Homo sapiens Q9Y2D8
Validated Y2H
25416956
Intra CARD9 Q9H257 SSX2IP Homo sapiens Q9Y2D8
Y2H Array
25416956
Intra CARD9 Q9H257 SSX2IP Homo sapiens Q9Y2D8
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 TNFAIP1 Homo sapiens Q13829
Y2H Array
25416956
Intra CARD9 Q9H257 BLZF1 Homo sapiens Q9H2G9
Validated Y2H
25416956
Intra CARD9 Q9H257 BLZF1 Homo sapiens Q9H2G9
Y2H Array
25416956
Intra CARD9 Q9H257 HMBOX1 Homo sapiens Q6NT76
Validated Y2H
25416956
Intra CARD9 Q9H257 PPP1R18 Homo sapiens Q6NYC8
Validated Y2H
25416956
Intra CARD9 Q9H257 PBX2 Homo sapiens P40425
Validated Y2H
25416956
Intra CARD9 Q9H257 PBX2 Homo sapiens P40425
Y2H Array
25416956
Intra CARD9 Q9H257 EIF4E2 Homo sapiens O60573
Validated Y2H
25416956
Intra CARD9 Q9H257 EIF4E2 Homo sapiens O60573
Y2H Array
25416956
Intra CARD9 Q9H257 KCTD9 Homo sapiens Q7L273
Validated Y2H
25416956
Intra CARD9 Q9H257 KCTD9 Homo sapiens Q7L273
Y2H Array
25416956
Intra CARD9 Q9H257 ABLIM1 Homo sapiens O14639
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 ABLIM1 Homo sapiens O14639
Validated Y2H
25416956
Intra CARD9 Q9H257 TRIM42 Homo sapiens Q8IWZ5
Validated Y2H
25416956
Intra CARD9 Q9H257 TRIM42 Homo sapiens Q8IWZ5
Y2H Array
25416956
Intra CARD9 Q9H257 CDCA7L Homo sapiens Q96GN5
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 CDCA7L Homo sapiens Q96GN5
Y2H Array
29892012
Intra CARD9 Q9H257 CDCA7L Homo sapiens Q96GN5
Validated Y2H
25416956
Intra CARD9 Q9H257 CWF19L2 Homo sapiens Q2TBE0
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 ZNF655 Homo sapiens Q8N720
Validated Y2H
25416956
Intra CARD9 Q9H257 ZNF655 Homo sapiens Q8N720
Y2H Array
25416956
Intra CARD9 Q9H257 ZNF655 Homo sapiens Q8N720
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 TRIM29 Homo sapiens Q14134
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 TRIM29 Homo sapiens Q14134
Validated Y2H
25416956
Intra CARD9 Q9H257 TRIM29 Homo sapiens Q14134
Y2H Array
25416956
Intra CARD9 Q9H257 PHC2 Homo sapiens Q8IXK0
Validated Y2H
25416956
Intra CARD9 Q9H257 STX11 Homo sapiens O75558
Y2H Array
25416956
Intra CARD9 Q9H257 TLE5 Homo sapiens Q08117
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 TLE5 Homo sapiens Q08117
Validated Y2H
25416956
Intra CARD9 Q9H257 FAM161A Homo sapiens Q3B820
Validated Y2H
25416956
Intra CARD9 Q9H257 LENG1 Homo sapiens Q96BZ8
Y2H Array
25416956
Intra CARD9 Q9H257 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 C2CD6 Homo sapiens Q53TS8
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 C2CD6 Homo sapiens Q53TS8
Validated Y2H
25416956
Intra CARD9 Q9H257 ZNF417 Homo sapiens Q8TAU3
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 LZTS2 Homo sapiens Q9BRK4
Validated Y2H
25416956
Intra CARD9 Q9H257 FAM124B Homo sapiens Q9H5Z6
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 FAM124B Homo sapiens Q9H5Z6
Validated Y2H
25416956
Intra CARD9 Q9H257 PAK5 Homo sapiens Q9P286
Y2H Array
31515488
Intra CARD9 Q9H257 PAK5 Homo sapiens Q9P286
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 KRT19 Homo sapiens P08727
Y2H Array
25416956
Intra CARD9 Q9H257 KRT19 Homo sapiens P08727
Validated Y2H
25416956
Intra CARD9 Q9H257 KRT19 Homo sapiens P08727
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 MEOX2 Homo sapiens P50222
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 DUSP13B Homo sapiens Q9UII6
Validated Y2H
25416956
Intra CARD9 Q9H257 DUSP13B Homo sapiens Q9UII6
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 TCL1A Homo sapiens P56279
Y2H Array
25416956
Intra CARD9 Q9H257 DAXX Homo sapiens Q9UER7
Validated Y2H
25416956
Intra CARD9 Q9H257 SUMO1 Homo sapiens P63165
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 IHO1 Homo sapiens Q8IYA8
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 IHO1 Homo sapiens Q8IYA8
Validated Y2H
25416956
Intra CARD9 Q9H257 IHO1 Homo sapiens Q8IYA8
Y2H Array
25416956
Intra CARD9 Q9H257 LMO1 Homo sapiens P25800
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 C1orf94 Homo sapiens Q6P1W5
Validated Y2H
25416956
Intra CARD9 Q9H257 C1orf94 Homo sapiens Q6P1W5
Y2H Array
25416956
Intra CARD9 Q9H257 KRT31 Homo sapiens Q15323
Y2H Array
25416956
Intra CARD9 Q9H257 TCEANC Homo sapiens Q8N8B7
Y2H Prey Pooling
25416956
Intra CARD9 Q9H257 TCEANC Homo sapiens Q8N8B7
Validated Y2H
25416956
Intra CARD9 Q9H257 BCL10 Homo sapiens O95999
MAPPIT
25416956
Intra CARD9 Q9H257 BCL10 Homo sapiens O95999
Anti Bait CoIP
22267217
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Immunodeficiency 103 Fungal Infections

Predisposition To Invasive Fungal Disease Due To Card9 Deficiency

Candidiasis, Familial, 2

CANDF2

Candidiasis, Familial Chronic Mucocutaneous, Autosomal Recessive

Card9 Immunodeficiency

Familial Chronic Mucocutaneous Candidiasis

Invasive Candidiasis-Deep Dermatophytosis Syndrome

IMD103

Immunodeficiency 103, Susceptibility To Fungal Infections

Immunodeficiency 103, Susceptibility To Fungal Infection

Immunodeficiency 103 Fungal Infection

Autosomal Recessive Candidiasis Familial Chronic Mucocutaneous

Card9 Deficiency

Familial Chronic Mucocutaneous Candidiasis Autosomal Recessive

Candidiasis Familial Chronic Mucocutaneous, Autosomal Recessive

Candidiasis, Familial, Type 2

Candidiasis

Systemic Candidiasis

Invasive Candidiasis

Disseminated Candidiasis

Systemic Candida Infections

Candidiasis, Invasive

Phaeohyphomycosis

Infection By Dematiacious Fungi

Phaehyphomycosis

Phaeomycosis

Pheohyphomycosis

Infection By Dematiacious Fungi [Phaehyphomycosis]

Dematiaceous Fungal Infection

Endophthalmitis
Sporotrichosis

Rose Gardener'S Disease

Meningoencephalitis

Acquired Toxoplasmal Meningoencephalitis

Meningoencephalitis Due To Acquired Toxoplasmosis

Meningoencephalitis Due To Toxoplasmosis

Toxoplasma Meningoencephalitis

Dermatophytosis

Tinea

Dermatophytosis, Unspecified

Ringworm

Infections Due To Species Of Epidermophyton, Microsporum And Trichophyton

Cutaneous Mycosis

Dermal Mycosis

Superficial Mycosis, Unspecified

Fungus Infection Of Skin

Skin Mycosis

Dermatitis Fungoid

Fungal Dermatitis

Fungal Dermatosis

Mycotic Infection Of Skin

Tinea Profunda

Deep Seated Dermatophytosis

Granuloma Trichophyticum

Majocchi'S Granuloma

Tinea Corporis

Dermatophytosis Of The Body

Dermatophytosis Of The Trunk

Cutaneous Candidiasis

Candidiasis, Cutaneous

Fungal Infectious Disease

Mycoses

Mycosis

Tinea Cruris

Dermatophytosis Of Groin & Perianal Area

Dermatophytosis Of Groin And Perianal Area

Dhobie Itch

Tinea Of Perianal Region

Subcutaneous Mycosis

Subcutaneous Fungal Disease

Tinea Barbae

Dermatophytosis Of Beard

Primary Systemic Mycosis
Opportunistic Mycosis

Opportunistic Mycoses

Opportunistic Systemic Mycoses

Tinea Capitis

Dermatophytosis Of Scalp

Scalp Ringworm

Dermatophytosis Of Scalp Or Beard

Tinea Capitis Due To Trichophyton Rubrum

Trichophyton Rubrum Tinea Capitis

Tinea Pedis

Athlete'S Foot

Dermatophytosis Of Foot

Ringworm Of Foot

Moccasin Foot

Vulvovaginal Candidiasis

Candidiasis Of Vulva And Vagina

Candidiasis, Vulvovaginal

Candidal Vulvovaginitis

Candidal: Cervix

Monilial Vulvovaginitis

Candidiasis Vulvovaginal

Nail Disease

Nail Diseases

Abnormality Of The Nail

Nail Anomaly

Tinea Unguium

Dermatophytosis Of Nail

Onychomycosis Due To Dermatophyte

Cellulitis And Abscess

Cellulitis And Abscess Of Buttock

Cellulitis And Abscess Of Face

Cellulitis And Abscess Of Finger

Cellulitis And Abscess Of Finger And Toe

Cellulitis And Abscess Of Gluteal Region

Cellulitis And Abscess Of Trunk

Cellulitis And Abscess Of Upper Arm And Forearm

Dermatophytic Onychia

Dermatophytic Onychomycosis

Onychomycosis

Ringworm Of Nails

Tinea Of Nail

Dermatomycosis

Dermatomycoses

Immunodeficiency 11b With Atopic Dermatitis

IMD11B

Atopic Dermatitis, Elevated Ige, And Eosinophilia

Immunodeficiency 11b

Tinea Manuum

Tinea Manus

Dermatophytosis Of Hand

Superficial Mycosis

Piedra

Steroid-Modified Tinea Infection

Tinea Imbricata

Kerion Celsi

Trichophyton Infection

Tinea Imbricata, Susceptibility To

Susceptibility To Tinea Imbricata

Tinea Capitis Profunda

Trichophytia Profunda Barbae

Trichophytia Profunda Capitis

Tinea Capitis

Chromoblastomycosis

Chromomycosis

Mossy Foot Disease

Verrucous Dermatitis

Fonseca Disease

Pedroso Disease

Drechslera Hawaiiensis

Drechslera Infection

Trichosporonosis
Chronic Mucocutaneous Candidiasis

Candidiasis, Chronic Mucocutaneous

Cmc

Candidiasis Chronic Mucocutaneous

Penicilliosis
Autoimmune Polyendocrine Syndrome

Autoimmune Polyendocrinopathy

Autoimmune Polyglandular Failure

Autoimmune Polyglandular Syndrome

Polyendocrinopathies, Autoimmune

Lloyd'S Syndrome

Aps

Polyendocrinopathies Autoimmune

Polyendocrine Autoimmunity Syndrome

Lloyd Syndrome

Polyglandular Autoimmune Deficiency

Progressive Pluriglandular Insufficiency

Pluriglandular Autoimmune Atrophy

Pluriglandular Autoimmune Syndrome

Thyroid-Adrenocortical Insufficiency Syndrome

Pityriasis Versicolor

Tinea Versicolor

Infection By Pityrosporum Furfur

Invasive Aspergillosis

Aspergillosis Invasive

Autoimmune Polyendocrine Syndrome Type 1

Whitaker Syndrome

Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy

Autoimmune Polyglandular Syndrome I

Polyglandular Type I Autoimmune Syndrome

Blastomycosis

Gilchrist'S Disease

North American Blastomycosis

Blastomyces Dermatitidis Infection

Blastomycotic Infection

Infection By Blastomyces Dermatitidis

Gilchrist Disease

Chicago Disease

Chicago Disease Or Disorder

Blastomycosis, Unspecified

Blastomyces Infection

Coccidioidomycosis

Valley Fever

Primary Extrapulmonary Coccidioidomycosis

Coccidioides Immitis Infection

Coccidiosis

Coccidioides Infection

Coccidioidomycosis, Unspecified

San Joaquin Fever

California Disease

Desert Fever

Desert Rheumatism

San Joaquin Valley Fever

Enteric Coccidiosis

Primary Pulmonary Coccidioidomycosis

Acute Coccidioidomycosis

Posadas Wernicke Disease

Vaginal Disease

Vaginal Diseases

Hyper Ige Recurrent Infection Syndrome 1

Job Syndrome

Hyper-Ige Recurrent Infection Syndrome 1

Hyperimmunoglobulin E Syndrome

Job'S Syndrome

Recurring Cold Staphylococcal Abscesses

Ige Syndromes

Buckley Syndrome

Hie - [Hyperimmunoglobulin E] Syndrome

Job-Buckley Syndrome

Quie-Hill Syndrome

Oral Candidiasis

Thrush

Candidiasis Of Mouth

Oral Moniliasis

Thrush, Oral

Candidiasis, Oral

Oral Thrush

Candidiasis

Equine Thrush

Immunodeficiency 11

Immunodeficiency 11a

Severe Combined Immunodeficiency Due To Card11 Deficiency

IMD11A

Imd11

Card11 Immunodeficiency

Scid Due To Card11 Deficiency

Card11 Deficiency

Immunodeficiency 11 A

Immunodeficiency 29

Mendelian Susceptibility To Mycobacterial Diseases Due To Complete Il12b Deficiency

IMD29

Il12b Deficiency

Immunodeficiency 29, Mycobacteriosis

Mendelian Susceptibility To Mycobacterial Diseases Due To Complete Interleukin 12b Deficiency

Msmd Due To Complete Il12b Deficiency

Msmd Due To Complete Interleukin 12b Deficiency

Immunodeficiency, Type 29, Mycobacteriosis

Esophageal Candidiasis

Candidiasis Of The Esophagus

Candida Esophagitis

Candidal Esophagitis

Esophageal Moniliasis

Esophageal Thrush

Mucormycosis

Zygomycosis

Disseminated Mucormycosis

Absidia Infection

Absidia Mucoromycosis

Cunninghamella Infection

Cunninghamella Mucoromycosis

Infection By Absidia Spp

Infection By Rhizopus Spp

Mucor Infection

Mucor Mucoromycosis

Infection By Mucor Spp

Rhizopus Infection

Rhizopus Mucoromycosis

Infection By Cunninghamella Spp

Phycomycosis Nos

Cryptococcosis

Cryptococcus Neoformans Infection

Torulosis

Busse-Buschke'S Disease

Cryptococcal Infection

European Cryptococcosis

Torula

Infection By Cryptococcus Neoformans

Cryptococcosis Infection

European Blastomycosis

European Blastomycotic Infection

European Blastomycoses Infection

Torula Histolytica Infection

Adenoiditis

Chronic Adenoiditis

Eumycotic Mycetoma

Eumycetoma

Maduromycosis

Mycetoma

Madura Foot

Maduromycosis, Mycotic

Mycotic Mycetoma

Mycetoma Of Foot

Eumycotic Maduromycosis

Mycetoma Due To Fungal Infection

Fungal Meningitis

Meningitis, Fungal

Mycotic Meningitis

Allergic Bronchopulmonary Aspergillosis

Aspergillosis, Allergic Bronchopulmonary

Abpa

Allergic Bronchopulmonary Mycosis

Hinson-Pepys Disease

Pulmonary Aspergillus Disease

Allergic Aspergillosis

Aspergillosis Allergic Bronchopulmonary

Hyper Ige Syndrome

Hyper-Ige Syndrome

Hyper Immunoglobulin E Syndrome

Hies

Hyper-Ige Recurrent Infection Syndrome

Hyperimmunoglobulin E Syndrome

Hyper Ige

Job Syndrome

Hartnup Disease

Immunodeficiency 27b

Autosomal Dominant Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Ifngammar1 Deficiency

IMD27B

Immunodeficiency 27b, Mycobacteriosis, Autosomal Dominant

Ifngr1 Deficiency, Autosomal Dominant

Autosomal Dominant Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Interferon Gamma Receptor 1 Deficiency

Autosomal Dominant Msmd Due To Partial Ifngammar1 Deficiency

Autosomal Dominant Msmd Due To Partial Interferon Gamma Receptor 1 Deficiency

Immunodeficiency 27b, Mycobacteriosis, Ad

Autosomal Dominant Ifngr1 Deficiency

Autosomal Dominant Immunodeficiency 27b, Mycobacteriosis

Immunodeficiency, Type 27b, Mycobacteriosis, Autosomal Dominant

Pneumocystosis

Pneumocystis Jirovecii Pneumonia

Pneumocystis Carinii Pneumonia

Pneumocystis Pneumonia

Pulmonary Pneumocystosis

PCP

Pneumocystosis Pneumonia

Pneumonia Pneumocystis Carinii

Pneumonia, Pneumocystis

Pneumocystis Jiroveci Pneumonia

Immunodeficiency 27a

IMD27A

Autosomal Recessive Ifngr1 Deficiency

Autosomal Recessive Immunodeficiency 27a, Mycobacteriosis

Autosomal Recessive Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Ifngammar1 Deficiency

Autosomal Recessive Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Interferon Gamma Receptor 1 Deficiency

Autosomal Recessive Msmd Due To Partial Ifngammar1 Deficiency

Autosomal Recessive Msmd Due To Partial Interferon Gamma Receptor 1 Deficiency

Immunodeficiency 27a, Mycobacteriosis, Autosomal Recessive

Ifngr1 Deficiency, Autosomal Recessive

Immunodeficiency 27a, Mycobacteriosis, Ar

Mendelian Susceptibility To Mycobacterial Diseases Due To Complete Ifngammar1 Deficiency

Msmd Due To Complete Ifngammar1 Deficiency

Msmd Due To Complete Interferon Gamma Receptor 1 Deficiency

Mendelian Susceptibility To Mycobacterial Diseases Due To Complete Interferon Gamma Receptor 1 Deficiency

Familial Disseminated Atypical Mycobacterial Infection

Interferon Gamma, Receptor 1, Deficiency

Immunodeficiency, Type 27a, Mycobacteriosis, Ar

Mycobacterial Disease, Mendelian Susceptibility To

Inflammatory Bowel Disease 1

Inflammatory Bowel Disease 1

IBD1

Crohn Disease-Associated Growth Failure

Crohn Disease

Regional Enteritis

Ulcerative Colitis

Crohn Disease-Associated Growth Failure, Susceptibility To

Inflammatory Bowel Disease 1, Crohn Disease

Bowel Disease, Inflammatory, Type 1

Crohn'S Disease

Crohn Disease

Pediatric Crohn'S Disease

Regional Enteritis

Crohn'S Disease Of Large Bowel

Granulomatous Colitis

Enteritis, Granulomatous

Enteritis

Crohn'S Disease Of Colon

Colitis, Granulomatous

Crohn'S Enteritis

Enteritis, Regional

Ileitis

Adenoviral Enteritis

Acute Gastroenteropathy Due To Norwalk Agent

Viral Gastroenteritis Due To Norwalk Agent

Winter Vomiting

Epidemic Winter Vomiting Disease

Small Round Structured Virus Enteritis

Epidemic Vomiting Syndrome

Epidemic Vomiting

Epidemic Nausea

Epidemic Viral Gastroenteritis Due To Norwalk Virus

Noroviral Enteritis

Crohn Disease Nos

Crohns

Cd - [Crohn'S Disease]

Regional Enteritis Of Bowel

Crohn'S Regional Enteritis

Cobble-Stone Appearance Of Intestine

Intestinal Ulcer And Erosion Due To Crohn Disease

Granulomatous Enteritis

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris CARD9 VGNC VGNC:38718
Rattus norvegicus CARD9 RGD RGD:708370
Macaca mulatta CARD9 VGNC VGNC:70567
Mus musculus CARD9 MGD MGI:2685628
Bos taurus CARD9 VGNC VGNC:26764