1. Gene
  2. IHO1 - interactor of HORMAD1 1 Gene

IHO1 - interactor of HORMAD1 1 Gene

中文名称:HORMAD1 1 的交互器

种属: Homo sapiens

同用名: CT74; LELA1; CCDC36

基因 ID: 339834 | 基因类型: protein coding

关于 IHO1

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:49,191,309-49,258,106 (from NCBI)

This gene has 5 transcripts (splice variants) and 117 orthologues. Biased expression in testis (RPKM 12.6), fat (RPKM 1.6) and 1 other tissue.

功能概要

预计参与配子生成;减数分裂 I 细胞周期过程;和同源染色体分离的调节。预测在浓缩核染色体中有活性。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in gamete generation; meiosis I cell cycle process; and regulation of homologous chromosome segregation. Predicted to be active in condensed nuclear chromosome. [provided by Alliance of Genome Resources, Apr 2022]

IHO1 基因产物(2)

mRNA Protein Name
NM_001135197.2 NP_001128669.1 interactor of HORMAD1 protein 1
NM_178173.4 NP_835467.2 interactor of HORMAD1 protein 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21516116 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

interactor of HORMAD1 protein 1

cancer/testis antigen 74

IHO1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra IHO1 Q8IYA8 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
32296183
Intra IHO1 Q8IYA8 IQUB Homo sapiens Q8NA54
Y2H Array
31515488
Intra IHO1 Q8IYA8 IQUB Homo sapiens Q8NA54
Y2H Array
25416956
Intra IHO1 Q8IYA8 RUNX1T1 Homo sapiens Q06455-4
Validated Y2H
25416956
Intra IHO1 Q8IYA8 RUNX1T1 Homo sapiens Q06455-4
Y2H Prey Pooling
25416956
Intra IHO1 Q8IYA8 NFKBID Homo sapiens Q8NI38
Validated Y2H
32296183
Intra IHO1 Q8IYA8 NGB Homo sapiens Q9NPG2
Validated Y2H
32296183
Intra IHO1 Q8IYA8 NGB Homo sapiens Q9NPG2
Y2H Array
25416956
Intra IHO1 Q8IYA8 NGB Homo sapiens Q9NPG2
Validated Y2H
25416956
Intra IHO1 Q8IYA8 PRKAB2 Homo sapiens O43741
Y2H Prey Pooling
25416956
Intra IHO1 Q8IYA8 PRKAB2 Homo sapiens O43741
Validated Y2H
27107012
Intra IHO1 Q8IYA8 COX5B Homo sapiens P10606
Y2H
21516116
Intra IHO1 Q8IYA8 ABI2 Homo sapiens Q9NYB9-2
Validated Y2H
32296183
Intra IHO1 Q8IYA8 CARD9 Homo sapiens Q9H257-2
Validated Y2H
32296183
Intra IHO1 Q8IYA8 NEK6 Homo sapiens Q9HC98-4
Validated Y2H
32296183
Intra IHO1 Q8IYA8 ATN1 Homo sapiens Q86V38
Y2H Array
32814053
Intra IHO1 Q8IYA8 ATN1 Homo sapiens Q86V38
Validated Y2H
32814053
Intra IHO1 Q8IYA8 ATN1 Homo sapiens Q86V38
Y2H Pooling
32814053
Intra IHO1 Q8IYA8 PRR34 Homo sapiens Q9NV39
Validated Y2H
32296183
Intra IHO1 Q8IYA8 FAM124B Homo sapiens Q9H5Z6-2
Validated Y2H
32296183
Intra IHO1 Q8IYA8 KIFC3 Homo sapiens Q9BVG8-5
Validated Y2H
32296183
Intra IHO1 Q8IYA8 RABGEF1 Homo sapiens Q9UJ41-4
Validated Y2H
32296183
Intra IHO1 Q8IYA8 KLC3 Homo sapiens Q6P597
Y2H Array
25416956
Intra IHO1 Q8IYA8 KLC3 Homo sapiens Q6P597
Validated Y2H
25416956
Intra IHO1 Q8IYA8 ZKSCAN3 Homo sapiens Q9BRR0
Validated Y2H
32296183
Intra IHO1 Q8IYA8 FANCL Homo sapiens Q9NW38
Validated Y2H
25416956
Intra IHO1 Q8IYA8 FANCL Homo sapiens Q9NW38
Y2H Array
25416956
Intra IHO1 Q8IYA8 LONRF1 Homo sapiens Q17RB8
Validated Y2H
25416956
Intra IHO1 Q8IYA8 KLK6 Homo sapiens Q92876
Y2H Array
32814053
Intra IHO1 Q8IYA8 KLK6 Homo sapiens Q92876
Y2H Pooling
32814053
Intra IHO1 Q8IYA8 KLK6 Homo sapiens Q92876
Validated Y2H
32814053
Intra IHO1 Q8IYA8 USP20 Homo sapiens Q9Y2K6
Y2H Array
25416956
Intra IHO1 Q8IYA8 USP20 Homo sapiens Q9Y2K6
Y2H Prey Pooling
25416956
Intra IHO1 Q8IYA8 KANK2 Homo sapiens Q63ZY3
Y2H Prey Pooling
25416956
Intra IHO1 Q8IYA8 KLHL11 Homo sapiens Q9NVR0
Validated Y2H
32296183
Intra IHO1 Q8IYA8 DYNLL1 Homo sapiens P63167
Y2H Array
25416956
Intra IHO1 Q8IYA8 CDC23 Homo sapiens Q9UJX2
Y2H Prey Pooling
25416956
Intra IHO1 Q8IYA8 CDC23 Homo sapiens Q9UJX2
Validated Y2H
25416956
Intra IHO1 Q8IYA8 CDC23 Homo sapiens Q9UJX2
Validated Y2H
32296183
Intra IHO1 Q8IYA8 TRIM42 Homo sapiens Q8IWZ5
Y2H Prey Pooling
25416956
Intra IHO1 Q8IYA8 HEXIM2 Homo sapiens Q96MH2
Y2H Array
25416956
Intra IHO1 Q8IYA8 STK25 Homo sapiens O00506
Y2H Array
25416956
Intra IHO1 Q8IYA8 SDCBP Homo sapiens O00560
Validated Y2H
25416956
Intra IHO1 Q8IYA8 SDCBP Homo sapiens O00560
Y2H Array
25416956
Intra IHO1 Q8IYA8 LMO2 Homo sapiens P25791
Validated Y2H
25416956
Intra IHO1 Q8IYA8 LMO2 Homo sapiens P25791
Y2H Array
25416956
Intra IHO1 Q8IYA8 LNX1 Homo sapiens Q8TBB1
Validated Y2H
32296183
Intra IHO1 Q8IYA8 NEK6 Homo sapiens Q9HC98
Y2H Array
25416956
Intra IHO1 Q8IYA8 GYS1 Homo sapiens P13807
Validated Y2H
25416956
Intra IHO1 Q8IYA8 GYS1 Homo sapiens P13807
Y2H Array
25416956
Intra IHO1 Q8IYA8 ZNF417 Homo sapiens Q8TAU3
Validated Y2H
32296183
Intra IHO1 Q8IYA8 ABI3 Homo sapiens Q9P2A4
Validated Y2H
32296183
Intra IHO1 Q8IYA8 EXOC8 Homo sapiens Q8IYI6
Validated Y2H
32296183
Intra IHO1 Q8IYA8 DYNLL2 Homo sapiens Q96FJ2
Y2H Prey Pooling
25416956
Intra IHO1 Q8IYA8 DYNLL2 Homo sapiens Q96FJ2
Validated Y2H
25416956
Intra IHO1 Q8IYA8 DYNLL2 Homo sapiens Q96FJ2
Y2H Array
25416956
Intra IHO1 Q8IYA8 USP2 Homo sapiens O75604
Y2H Array
25416956
Intra IHO1 Q8IYA8 ABI2 Homo sapiens Q9NYB9
Y2H
21516116
Intra IHO1 Q8IYA8 ABI2 Homo sapiens Q9NYB9
Y2H Array
29892012
Intra IHO1 Q8IYA8 ABI2 Homo sapiens Q9NYB9
Y2H Prey Pooling
25416956
Intra IHO1 Q8IYA8 FAM124A Homo sapiens Q86V42
Y2H Array
25416956
Intra IHO1 Q8IYA8 CCDC120 Homo sapiens Q96HB5
Validated Y2H
32296183
Intra IHO1 Q8IYA8 FKBP6 Homo sapiens O75344
Y2H Array
25416956
Intra IHO1 Q8IYA8 FKBP6 Homo sapiens O75344
Y2H Array
29892012
Intra IHO1 Q8IYA8 FKBP6 Homo sapiens O75344
Y2H Array
31515488
Intra IHO1 Q8IYA8 AQP1 Homo sapiens P29972
Y2H Prey Pooling
25416956
Intra IHO1 Q8IYA8 MAGOHB Homo sapiens Q96A72
Validated Y2H
32296183
Intra IHO1 Q8IYA8 MRFAP1L1 Homo sapiens Q96HT8
Validated Y2H
25416956
Intra IHO1 Q8IYA8 CFAP206 Homo sapiens Q8IYR0
Validated Y2H
32296183
Intra IHO1 Q8IYA8 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Intra IHO1 Q8IYA8 KIF9 Homo sapiens Q9HAQ2
Validated Y2H
32296183
Intra IHO1 Q8IYA8 KIF9 Homo sapiens Q9HAQ2
Y2H Prey Pooling
32296183
Intra IHO1 Q8IYA8 AIRIM Homo sapiens Q9NX04
Validated Y2H
32296183
Intra IHO1 Q8IYA8 TTC19 Homo sapiens Q6DKK2
Validated Y2H
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Infertility
Male Infertility

Infertility, Male

Infertility Male

Male Sterility

Absolute Infertility

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus IHO1 MGD MGI:3612242
Felis catus IHO1 VGNC VGNC:60498
Bos taurus IHO1 VGNC VGNC:26893
Macaca mulatta IHO1 VGNC VGNC:110359
Rattus norvegicus IHO1 RGD RGD:1596869
Canis familiaris IHO1 VGNC VGNC:38836