IHO1 - interactor of HORMAD1 1 Gene

中文名称：HORMAD1 1 的交互器

种属: Homo sapiens

同用名: CT74; LELA1; CCDC36

基因 ID: 339834 | 基因类型: protein coding

关于 IHO1

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:49,191,309-49,258,106 (from NCBI)

This gene has 5 transcripts (splice variants) and 117 orthologues. Biased expression in testis (RPKM 12.6), fat (RPKM 1.6) and 1 other tissue.

功能概要

预计参与配子生成；减数分裂 I 细胞周期过程；和同源染色体分离的调节。预测在浓缩核染色体中有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in gamete generation; meiosis I cell cycle process; and regulation of homologous chromosome segregation. Predicted to be active in condensed nuclear chromosome. [provided by Alliance of Genome Resources, Apr 2022]

IHO1 基因产物(2)

mRNA	Protein	Name
NM_001135197.2	NP_001128669.1	interactor of HORMAD1 protein 1
NM_178173.4	NP_835467.2	interactor of HORMAD1 protein 1

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	21516116	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

蛋白主名

其他名称

interactor of HORMAD1 protein 1

cancer/testis antigen 74

IHO1 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	IHO1	Q8IYA8	MID2	Homo sapiens	Q9UJV3-2	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	IQUB	Homo sapiens	Q8NA54	Y2H Array	31515488
Intra	IHO1	Q8IYA8	IQUB	Homo sapiens	Q8NA54	Y2H Array	25416956
Intra	IHO1	Q8IYA8	RUNX1T1	Homo sapiens	Q06455-4	Validated Y2H	25416956
Intra	IHO1	Q8IYA8	RUNX1T1	Homo sapiens	Q06455-4	Y2H Prey Pooling	25416956
Intra	IHO1	Q8IYA8	NFKBID	Homo sapiens	Q8NI38	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	NGB	Homo sapiens	Q9NPG2	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	NGB	Homo sapiens	Q9NPG2	Y2H Array	25416956
Intra	IHO1	Q8IYA8	NGB	Homo sapiens	Q9NPG2	Validated Y2H	25416956
Intra	IHO1	Q8IYA8	PRKAB2	Homo sapiens	O43741	Y2H Prey Pooling	25416956
Intra	IHO1	Q8IYA8	PRKAB2	Homo sapiens	O43741	Validated Y2H	27107012
Intra	IHO1	Q8IYA8	COX5B	Homo sapiens	P10606	Y2H	21516116
Intra	IHO1	Q8IYA8	ABI2	Homo sapiens	Q9NYB9-2	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	CARD9	Homo sapiens	Q9H257-2	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	NEK6	Homo sapiens	Q9HC98-4	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	ATN1	Homo sapiens	Q86V38	Y2H Array	32814053
Intra	IHO1	Q8IYA8	ATN1	Homo sapiens	Q86V38	Validated Y2H	32814053
Intra	IHO1	Q8IYA8	ATN1	Homo sapiens	Q86V38	Y2H Pooling	32814053
Intra	IHO1	Q8IYA8	PRR34	Homo sapiens	Q9NV39	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	FAM124B	Homo sapiens	Q9H5Z6-2	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	KIFC3	Homo sapiens	Q9BVG8-5	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	RABGEF1	Homo sapiens	Q9UJ41-4	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	KLC3	Homo sapiens	Q6P597	Y2H Array	25416956
Intra	IHO1	Q8IYA8	KLC3	Homo sapiens	Q6P597	Validated Y2H	25416956
Intra	IHO1	Q8IYA8	ZKSCAN3	Homo sapiens	Q9BRR0	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	FANCL	Homo sapiens	Q9NW38	Validated Y2H	25416956
Intra	IHO1	Q8IYA8	FANCL	Homo sapiens	Q9NW38	Y2H Array	25416956
Intra	IHO1	Q8IYA8	LONRF1	Homo sapiens	Q17RB8	Validated Y2H	25416956
Intra	IHO1	Q8IYA8	KLK6	Homo sapiens	Q92876	Y2H Array	32814053
Intra	IHO1	Q8IYA8	KLK6	Homo sapiens	Q92876	Y2H Pooling	32814053
Intra	IHO1	Q8IYA8	KLK6	Homo sapiens	Q92876	Validated Y2H	32814053
Intra	IHO1	Q8IYA8	USP20	Homo sapiens	Q9Y2K6	Y2H Array	25416956
Intra	IHO1	Q8IYA8	USP20	Homo sapiens	Q9Y2K6	Y2H Prey Pooling	25416956
Intra	IHO1	Q8IYA8	KANK2	Homo sapiens	Q63ZY3	Y2H Prey Pooling	25416956
Intra	IHO1	Q8IYA8	KLHL11	Homo sapiens	Q9NVR0	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	DYNLL1	Homo sapiens	P63167	Y2H Array	25416956
Intra	IHO1	Q8IYA8	CDC23	Homo sapiens	Q9UJX2	Y2H Prey Pooling	25416956
Intra	IHO1	Q8IYA8	CDC23	Homo sapiens	Q9UJX2	Validated Y2H	25416956
Intra	IHO1	Q8IYA8	CDC23	Homo sapiens	Q9UJX2	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	TRIM42	Homo sapiens	Q8IWZ5	Y2H Prey Pooling	25416956
Intra	IHO1	Q8IYA8	HEXIM2	Homo sapiens	Q96MH2	Y2H Array	25416956
Intra	IHO1	Q8IYA8	STK25	Homo sapiens	O00506	Y2H Array	25416956
Intra	IHO1	Q8IYA8	SDCBP	Homo sapiens	O00560	Validated Y2H	25416956
Intra	IHO1	Q8IYA8	SDCBP	Homo sapiens	O00560	Y2H Array	25416956
Intra	IHO1	Q8IYA8	LMO2	Homo sapiens	P25791	Validated Y2H	25416956
Intra	IHO1	Q8IYA8	LMO2	Homo sapiens	P25791	Y2H Array	25416956
Intra	IHO1	Q8IYA8	LNX1	Homo sapiens	Q8TBB1	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	NEK6	Homo sapiens	Q9HC98	Y2H Array	25416956
Intra	IHO1	Q8IYA8	GYS1	Homo sapiens	P13807	Validated Y2H	25416956
Intra	IHO1	Q8IYA8	GYS1	Homo sapiens	P13807	Y2H Array	25416956
Intra	IHO1	Q8IYA8	ZNF417	Homo sapiens	Q8TAU3	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	ABI3	Homo sapiens	Q9P2A4	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	EXOC8	Homo sapiens	Q8IYI6	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	DYNLL2	Homo sapiens	Q96FJ2	Y2H Prey Pooling	25416956
Intra	IHO1	Q8IYA8	DYNLL2	Homo sapiens	Q96FJ2	Validated Y2H	25416956
Intra	IHO1	Q8IYA8	DYNLL2	Homo sapiens	Q96FJ2	Y2H Array	25416956
Intra	IHO1	Q8IYA8	USP2	Homo sapiens	O75604	Y2H Array	25416956
Intra	IHO1	Q8IYA8	ABI2	Homo sapiens	Q9NYB9	Y2H	21516116
Intra	IHO1	Q8IYA8	ABI2	Homo sapiens	Q9NYB9	Y2H Array	29892012
Intra	IHO1	Q8IYA8	ABI2	Homo sapiens	Q9NYB9	Y2H Prey Pooling	25416956
Intra	IHO1	Q8IYA8	FAM124A	Homo sapiens	Q86V42	Y2H Array	25416956
Intra	IHO1	Q8IYA8	CCDC120	Homo sapiens	Q96HB5	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	FKBP6	Homo sapiens	O75344	Y2H Array	25416956
Intra	IHO1	Q8IYA8	FKBP6	Homo sapiens	O75344	Y2H Array	29892012
Intra	IHO1	Q8IYA8	FKBP6	Homo sapiens	O75344	Y2H Array	31515488
Intra	IHO1	Q8IYA8	AQP1	Homo sapiens	P29972	Y2H Prey Pooling	25416956
Intra	IHO1	Q8IYA8	MAGOHB	Homo sapiens	Q96A72	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	MRFAP1L1	Homo sapiens	Q96HT8	Validated Y2H	25416956
Intra	IHO1	Q8IYA8	CFAP206	Homo sapiens	Q8IYR0	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	PICK1	Homo sapiens	Q9NRD5	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	KIF9	Homo sapiens	Q9HAQ2	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	KIF9	Homo sapiens	Q9HAQ2	Y2H Prey Pooling	32296183
Intra	IHO1	Q8IYA8	AIRIM	Homo sapiens	Q9NX04	Validated Y2H	32296183
Intra	IHO1	Q8IYA8	TTC19	Homo sapiens	Q6DKK2	Validated Y2H	25416956

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Infertility

Male Infertility

Infertility, Male	Infertility Male
Male Sterility	Absolute Infertility

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS06655	IHO1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	IHO1	MGD	MGI:3612242
Felis catus	IHO1	VGNC	VGNC:60498
Bos taurus	IHO1	VGNC	VGNC:26893
Macaca mulatta	IHO1	VGNC	VGNC:110359
Rattus norvegicus	IHO1	RGD	RGD:1596869
Canis familiaris	IHO1	VGNC	VGNC:38836

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