2. Gene
  3. KLHL11 - kelch like family member 11 Gene

KLHL11 - kelch like family member 11 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：kelch 样家族成员 11

种属: Homo sapiens

基因 ID: 55175 | 基因类型: protein coding

关于 KLHL11

Cytogenetic location: 17q21.2 Genomic coordinates (GRCh38): 17:41,848,518-41,865,423 (from NCBI)

This gene has 1 transcript (splice variant), 250 orthologues and 11 paralogues. Broad expression in testis (RPKM 5.8), brain (RPKM 4.6) and 25 other tissues.

功能概要

预测位于胞质溶胶中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

KLHL11 基因产物(1)

mRNA Protein Name
NM_018143.3 NP_060613.1 kelch-like protein 11 precursor

KLHL11 蛋白结构

BTB

BTB: BTB/POZ domain (85 - 199)

BACK

BACK: BTB And C-terminal Kelch (205 - 307)

Kelch_1

Kelch_1: Kelch motif (398 - 439)

Kelch_1

Kelch_1: Kelch motif (443 - 486)

Kelch_1

Kelch_1: Kelch motif (601 - 648)

  • 0
  • 200
  • 400
  • 600
  • 708 a.a.
蛋白主名 其他名称

kelch-like protein 11

KLHL11 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
KLHL11 Q9NVR0 POU6F2 Homo sapiens P78424
Y2H Array
32296183
种属内
KLHL11 Q9NVR0 POU6F2 Homo sapiens P78424
Y2H Prey Pooling
32296183
种属内
KLHL11 Q9NVR0 IHO1 Homo sapiens Q8IYA8
Y2H Prey Pooling
32296183
种属内
KLHL11 Q9NVR0 IHO1 Homo sapiens Q8IYA8
Y2H Array
32296183
种属内
KLHL11 Q9NVR0 UBQLN2 Homo sapiens Q9UHD9
Y2H Prey Pooling
32296183
种属内
KLHL11 Q9NVR0 UBQLN2 Homo sapiens Q9UHD9
Validated Y2H
32296183
种属内
KLHL11 Q9NVR0 UBQLN2 Homo sapiens Q9UHD9
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Polyradiculopathy
Acquired Night Blindness
Cold-Induced Sweating Syndrome 3
Ulnar Nerve Lesion

Lesion Of Ulnar Nerve

Mononeuritis Ulnar Nerve

Tardy Ulnar Nerve Palsy
Spinal Cord Lymphoma

Lymphoma Of The Spinal Cord

Spinal Cord Cancer

Spine Lymphoma

Spinal Cord--Cancer
Internuclear Ophthalmoplegia

Ophthalmoplegia Internuclearis

Bielschowsky-Lutz-Cogan Syndrome

Ino - [Internuclear Ophthalmoplegia]

Lhermitte Syndrome

Mlf - [Medial Longitudinal Fasciculus] Syndrome

Internuclear Paralysis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07355 KLHL11 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus KLHL11 RGD RGD:1306673
Bos taurus KLHL11 VGNC VGNC:55842
Macaca mulatta KLHL11 VGNC VGNC:74083
Canis familiaris KLHL11 VGNC VGNC:42447
Felis catus KLHL11 VGNC VGNC:99094
Mus musculus KLHL11 MGD MGI:2388648
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