2. Gene
  3. TAF1D - TATA-box binding protein associated factor, RNA polymerase I subunit D Gene

TAF1D - TATA-box binding protein associated factor, RNA polymerase I subunit D Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：TATA-box 结合蛋白相关因子，RNA 聚合酶 I 亚基 D

种属: Homo sapiens

同用名: JOSD3; RAFI41; TAFI41; TAF(I)41

基因 ID: 79101 | 基因类型: protein coding

关于 TAF1D

Cytogenetic location: 11q21 Genomic coordinates (GRCh38): 11:93,730,194-93,741,495 (from NCBI)

This gene has 22 transcripts (splice variants) and 127 orthologues. Ubiquitous expression in lymph node (RPKM 25.5), appendix (RPKM 22.4) and 25 other tissues.

功能概要

TAF1D 是 SL1 复合体的成员，其中包括 TBP (MIM 600075) 和 TAF1A (MIM 604903) 、TAF1B (MIM 604904) 和 TAF1C (MIM 604905) ，并在 RNA 聚合酶 I 转录中发挥作用 (Wang et al. , 2004 [PubMed 15520167]；Gorski 等人，2007 [PubMed 17318177]) .[OMIM 提供，2009 年 6 月]

TAF1D is a member of the SL1 complex, which includes TBP (MIM 600075) and TAF1A (MIM 604903), TAF1B (MIM 604904), and TAF1C (MIM 604905), and plays a role in RNA polymerase I transcription (Wang et al., 2004 [PubMed 15520167]; Gorski et al., 2007 [PubMed 17318177]).[supplied by OMIM, Jun 2009]

TAF1D 基因产物(1)

mRNA Protein Name
NM_024116.4 NP_077021.1 TATA box-binding protein-associated factor RNA polymerase I subunit D
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
15520167 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TAF1D 蛋白结构

TAF1D

TAF1D: TATA box-binding protein-associated factor 1D (27 - 243)

  • 0
  • 100
  • 200
  • 278 a.a.
蛋白主名 其他名称

TATA box-binding protein-associated factor RNA polymerase I subunit D

Josephin domain containing 3

TAF1D 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra TAF1D Q9H5J8 POLB Homo sapiens P06746
IF
15520167
Intra TAF1D Q9H5J8 POLB Homo sapiens P06746
Y2H
15520167
Intra TAF1D Q9H5J8 POLB Homo sapiens P06746
Anti Tag CoIP
15520167
Intra TAF1D Q9H5J8 HAP1 Homo sapiens P54257
Y2H
21900206
Intra TAF1D Q9H5J8 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
25416956
Intra TAF1D Q9H5J8 TBP Homo sapiens P20226
Anti Tag CoIP
19615732
Intra TAF1D Q9H5J8 CEP70 Homo sapiens Q8NHQ1
Validated Y2H
25416956
Intra TAF1D Q9H5J8 TAF1D Homo sapiens Q9H5J8
Validated Y2H
32296183
Intra TAF1D Q9H5J8 HAP1 Homo sapiens P54257
Y2H Pooling
16169070
Intra TAF1D Q9H5J8 TAF1D Homo sapiens Q9H5J8
Y2H Prey Pooling
32296183
Intra TAF1D Q9H5J8 TAF1D Homo sapiens Q9H5J8
Y2H Array
32296183
Intra TAF1D Q9H5J8 PTN Homo sapiens P21246
Y2H Pooling
16169070
Intra TAF1D Q9H5J8 TBP Homo sapiens P20226
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Noonan Syndrome 1

Noonan Syndrome

NS1

Male Turner Syndrome

Female Pseudo-Turner Syndrome

Turner Phenotype With Normal Karyotype

Noonan Syndrome With Pigmented Villonodular Synovitis

Turner'S Phenotype, Karyotype Normal

Familial Turner Syndrome

Noonan'S Syndrome

Noonan-Ehmke Syndrome

Ns

Pseudo-Ullrich-Turner Syndrome

Turner Syndrome In Female With X Chromosome

Turner-Like Syndrome

Ullrich-Noonan Syndrome

Noonan-Like/Multiple Giant Cell Lesion Syndrome

Noonan Syndrome-Like Disorder With Multiple Giant Cell Lesions

Pterygium Colli Syndrome

Noonan Syndrome, Type 1

Turner Syndrome, Male
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14165 TAF1D Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta TAF1D VGNC VGNC:101413
Bos taurus TAF1D VGNC VGNC:35572
Felis catus TAF1D VGNC VGNC:65929
Rattus norvegicus TAF1D RGD RGD:1309627
Mus musculus TAF1D MGD MGI:1922566
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