1. Gene
  2. IPCEF1 - interaction protein for cytohesin exchange factors 1 Gene

IPCEF1 - interaction protein for cytohesin exchange factors 1 Gene

中文名称:细胞粘附素交换因子 1 的相互作用蛋白

种属: Homo sapiens

同用名: PIP3E; PIP3-E

基因 ID: 26034 | 基因类型: protein coding

关于 IPCEF1

Cytogenetic location: 6q25.2 Genomic coordinates (GRCh38): 6:154,154,496-154,356,803 (from NCBI)

This gene has 13 transcripts (splice variants), 97 orthologues and 4 paralogues. Biased expression in thyroid (RPKM 13.5), brain (RPKM 6.8) and 9 other tissues.

功能概要

预测可启用过氧化物酶活性。预计参与对氧化应激的反应。预测位于胞质溶胶和质膜中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable peroxidase activity. Predicted to be involved in response to oxidative stress. Predicted to be located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

IPCEF1 基因产物(7)

mRNA Protein Name
NM_001130699.2 NP_001124171.1 interactor protein for cytohesin exchange factors 1 isoform 1
NM_001130700.2 NP_001124172.1 interactor protein for cytohesin exchange factors 1 isoform 1
NM_001394799.1 NP_001381728.1 interactor protein for cytohesin exchange factors 1 isoform 1
NM_001394800.1 NP_001381729.1 interactor protein for cytohesin exchange factors 1 isoform 1
NM_001394801.1 NP_001381730.1 interactor protein for cytohesin exchange factors 1 isoform 1
NM_001394802.1 NP_001381731.1 interactor protein for cytohesin exchange factors 1 isoform 2
NM_015553.3 NP_056368.1 interactor protein for cytohesin exchange factors 1 isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
22085542 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

IPCEF1 蛋白结构

PH

PH: PH domain (44 - 137)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 437 a.a.
蛋白主名 其他名称

interactor protein for cytohesin exchange factors 1

interaction protein for cytohesin exchange factors 1 Interaction protein for cytohesin exchange factors 1

IPCEF1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra IPCEF1 Q8WWN9 CYTH4 Homo sapiens Q9UIA0
Y2H Prey Pooling
32296183
Intra IPCEF1 Q8WWN9 CYTH4 Homo sapiens Q9UIA0
Validated Y2H
32296183
Intra IPCEF1 Q8WWN9 CYTH4 Homo sapiens Q9UIA0
Anti Tag CoIP
33961781
Intra IPCEF1 Q8WWN9 CYTH4 Homo sapiens Q9UIA0
Y2H Array
32296183
Intra IPCEF1 Q8WWN9 CYTH2 Homo sapiens Q99418
Y2H Array
32296183
Intra IPCEF1 Q8WWN9 CYTH2 Homo sapiens Q99418
Anti Tag CoIP
33961781
Intra IPCEF1 Q8WWN9 CYTH2 Homo sapiens Q99418
Y2H Prey Pooling
32296183
Intra IPCEF1 Q8WWN9 CYTH2 Homo sapiens Q99418
Validated Y2H
32296183
Intra IPCEF1 Q8WWN9 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
32296183
Intra IPCEF1 Q8WWN9 CEP70 Homo sapiens Q8NHQ1
Y2H Array
32296183
Intra IPCEF1 Q8WWN9 CYTH1 Homo sapiens Q15438
Y2H Prey Pooling
32296183
Intra IPCEF1 Q8WWN9 CYTH1 Homo sapiens Q15438
Anti Tag CoIP
33961781
Intra IPCEF1 Q8WWN9 CYTH1 Homo sapiens Q15438
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Bos taurus IPCEF1 VGNC VGNC:30239
Mus musculus IPCEF1 MGD MGI:2444159
Macaca mulatta IPCEF1 VGNC VGNC:83429
Rattus norvegicus IPCEF1 RGD RGD:735159