1. Gene
  2. ZSCAN21 - zinc finger and SCAN domain containing 21 Gene

ZSCAN21 - zinc finger and SCAN domain containing 21 Gene

中文名称:含锌指和 SCAN 结构域 21

种属: Homo sapiens

同用名: ZNF38; Zipro1; NY-REN-21

基因 ID: 7589 | 基因类型: protein coding

关于 ZSCAN21

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:100,049,774-100,065,040 (from NCBI)

This gene has 4 transcripts (splice variants), 88 orthologues and 31 paralogues. Ubiquitous expression in testis (RPKM 4.9), endometrium (RPKM 3.1) and 25 other tissues.

功能概要

启用 DNA 结合转录激活因子活性、RNA 聚合酶 II 特异性和 RNA 聚合酶 II 顺式调节区序列特异性 DNA 结合活性。参与 RNA 聚合酶 II 对转录的正调控。预测位于核内。 [由基因组资源联盟提供,2022 年 4 月]

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZSCAN21 基因产物(4)

mRNA Protein Name
NM_001362779.2 NP_001349708.1 zinc finger and SCAN domain-containing protein 21 isoform 1
NM_001362780.2 NP_001349709.1 zinc finger and SCAN domain-containing protein 21 isoform 1
NM_001362781.2 NP_001349710.1 zinc finger and SCAN domain-containing protein 21 isoform 2
NM_145914.3 NP_666019.1 zinc finger and SCAN domain-containing protein 21 isoform 1

ZSCAN21 蛋白结构

SCAN

SCAN: SCAN domain (40 - 133)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (291 - 316)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (346 - 370)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (375 - 398)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (403 - 427)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (430 - 453)

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  • 473 a.a.
蛋白主名 其他名称

zinc finger and SCAN domain-containing protein 21

renal carcinoma antigen NY-REN-21

ZSCAN21 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ZSCAN21 Q9Y5A6 KRT40 Homo sapiens Q6A162 25416956
种属内
ZSCAN21 Q9Y5A6 KRTAP10-8 Homo sapiens P60410 32296183
种属内
ZSCAN21 Q9Y5A6 KRTAP10-8 Homo sapiens P60410 25416956
种属内
ZSCAN21 Q9Y5A6 KRTAP10-8 Homo sapiens P60410 32296183
种属内
ZSCAN21 Q9Y5A6 KRTAP10-9 Homo sapiens P60411 25416956
种属内
ZSCAN21 Q9Y5A6 KRTAP10-9 Homo sapiens P60411 25416956
种属内
ZSCAN21 Q9Y5A6 KRTAP10-5 Homo sapiens P60370 25416956
种属内
ZSCAN21 Q9Y5A6 KRTAP10-7 Homo sapiens P60409 32296183
种属内
ZSCAN21 Q9Y5A6 KRTAP10-7 Homo sapiens P60409 32296183
种属内
ZSCAN21 Q9Y5A6 ZSCAN22 Homo sapiens P10073 32296183
种属内
ZSCAN21 Q9Y5A6 ZSCAN22 Homo sapiens P10073 32296183
种属内
ZSCAN21 Q9Y5A6 ZNF483 Homo sapiens Q6P088 32296183
种属内
ZSCAN21 Q9Y5A6 ZNF483 Homo sapiens Q6P088 32296183
种属内
ZSCAN21 Q9Y5A6 ZKSCAN7 Homo sapiens Q9P0L1-2 32296183
种属内
ZSCAN21 Q9Y5A6 ZKSCAN7 Homo sapiens Q9P0L1-2 32296183
种属内
ZSCAN21 Q9Y5A6 KRTAP12-3 Homo sapiens P60328 32296183
种属内
ZSCAN21 Q9Y5A6 KRTAP12-3 Homo sapiens P60328 32296183
种属内
ZSCAN21 Q9Y5A6 ZNF837 Homo sapiens Q96EG3 32296183
种属内
ZSCAN21 Q9Y5A6 ZNF837 Homo sapiens Q96EG3 32296183
种属内
ZSCAN21 Q9Y5A6 ZSCAN12 Homo sapiens O43309 32296183
种属内
ZSCAN21 Q9Y5A6 ZSCAN12 Homo sapiens O43309 32296183
种属内
ZSCAN21 Q9Y5A6 ZNF396 Homo sapiens Q96N95-3 32296183
种属内
ZSCAN21 Q9Y5A6 ZNF396 Homo sapiens Q96N95-3 32296183
种属内
ZSCAN21 Q9Y5A6 ZNF213 Homo sapiens O14771 32296183
种属内
ZSCAN21 Q9Y5A6 ZNF213 Homo sapiens O14771 32296183
种属内
ZSCAN21 Q9Y5A6 CAVIN1 Homo sapiens Q6NZI2 32296183
种属内
ZSCAN21 Q9Y5A6 CAVIN1 Homo sapiens Q6NZI2 32296183
种属内
ZSCAN21 Q9Y5A6 ZNF24 Homo sapiens P17028 33961781
种属内
ZSCAN21 Q9Y5A6 ZNF24 Homo sapiens P17028 25416956
种属内
ZSCAN21 Q9Y5A6 ZNF24 Homo sapiens P17028 25416956
种属内
ZSCAN21 Q9Y5A6 ZNF24 Homo sapiens P17028 32296183
种属内
ZSCAN21 Q9Y5A6 ZNF24 Homo sapiens P17028 25416956
种属内
ZSCAN21 Q9Y5A6 ZNF24 Homo sapiens P17028 32296183
种属内
ZSCAN21 Q9Y5A6 TRIM41 Homo sapiens Q8WV44 25416956
种属内
ZSCAN21 Q9Y5A6 TRIM41 Homo sapiens Q8WV44 25416956
种属内
ZSCAN21 Q9Y5A6 TRIM41 Homo sapiens Q8WV44 25416956
种属内
ZSCAN21 Q9Y5A6 CEP70 Homo sapiens Q8NHQ1 32296183
种属内
ZSCAN21 Q9Y5A6 CEP70 Homo sapiens Q8NHQ1 32296183
种属内
ZSCAN21 Q9Y5A6 DVL3 Homo sapiens Q92997 32296183
种属内
ZSCAN21 Q9Y5A6 DVL3 Homo sapiens Q92997 32296183
种属内
ZSCAN21 Q9Y5A6 ZNF446 Homo sapiens Q9NWS9-2 25416956
种属内
ZSCAN21 Q9Y5A6 ZNF446 Homo sapiens Q9NWS9-2 25416956
种属内
ZSCAN21 Q9Y5A6 ZNF446 Homo sapiens Q9NWS9-2 25416956
种属内
ZSCAN21 Q9Y5A6 GRAP2 Homo sapiens O75791 32296183
种属内
ZSCAN21 Q9Y5A6 GRAP2 Homo sapiens O75791 32296183
种属内
ZSCAN21 Q9Y5A6 ZKSCAN7 Homo sapiens Q9P0L1 25416956
种属内
ZSCAN21 Q9Y5A6 ZNF496 Homo sapiens Q96IT1 32296183
种属内
ZSCAN21 Q9Y5A6 ZNF496 Homo sapiens Q96IT1 25416956
种属内
ZSCAN21 Q9Y5A6 ZNF496 Homo sapiens Q96IT1 32296183
种属内
ZSCAN21 Q9Y5A6 PICK1 Homo sapiens Q9NRD5 32296183
种属内
ZSCAN21 Q9Y5A6 PICK1 Homo sapiens Q9NRD5 32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Parkinson Disease, Late-Onset

Parkinson Disease

Parkinson'S Disease

PD

PARK

Parkinson Disease, Susceptibility To

Late Onset Parkinson'S Disease

Late Onset Parkinson Disease

Paralysis Agitans

Primary Parkinsonism

Idiopathic Parkinson Disease

Parkinson'S

Parkinson Disease, Late-Onset, Susceptibility To

Parkinson Disease, Age Of Onset, Modifier

Lewy Body Parkinson Disease

Idiopathic Parkinson'S Disease

Pd - [Parkinson Disease]

Parkinson Disease Nos

Parkinson, Nos

Primary Parkinson Disease

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta ZSCAN21 VGNC VGNC:81892
Bos taurus ZSCAN21 VGNC VGNC:37377
Canis familiaris ZSCAN21 VGNC VGNC:54101
Rattus norvegicus ZSCAN21 RGD RGD:1309981
Mus musculus ZSCAN21 MGD MGI:99182