1. Gene
  2. ZSCAN21 - zinc finger and SCAN domain containing 21 Gene

ZSCAN21 - zinc finger and SCAN domain containing 21 Gene

中文名称:含锌指和 SCAN 结构域 21

种属: Homo sapiens

同用名: ZNF38; Zipro1; NY-REN-21

基因 ID: 7589 | 基因类型: protein coding

关于 ZSCAN21

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:100,049,774-100,065,040 (from NCBI)

This gene has 4 transcripts (splice variants), 88 orthologues and 31 paralogues. Ubiquitous expression in testis (RPKM 4.9), endometrium (RPKM 3.1) and 25 other tissues.

功能概要

启用 DNA 结合转录激活因子活性、RNA 聚合酶 II 特异性和 RNA 聚合酶 II 顺式调节区序列特异性 DNA 结合活性。参与 RNA 聚合酶 II 对转录的正调控。预测位于核内。 [由基因组资源联盟提供,2022 年 4 月]

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZSCAN21 基因产物(4)

mRNA Protein Name
NM_001362779.2 NP_001349708.1 zinc finger and SCAN domain-containing protein 21 isoform 1
NM_001362780.2 NP_001349709.1 zinc finger and SCAN domain-containing protein 21 isoform 1
NM_001362781.2 NP_001349710.1 zinc finger and SCAN domain-containing protein 21 isoform 2
NM_145914.3 NP_666019.1 zinc finger and SCAN domain-containing protein 21 isoform 1

ZSCAN21 蛋白结构

SCAN

SCAN: SCAN domain (40 - 133)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (291 - 316)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (346 - 370)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (375 - 398)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (403 - 427)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (430 - 453)

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  • 473 a.a.
蛋白主名 其他名称

zinc finger and SCAN domain-containing protein 21

renal carcinoma antigen NY-REN-21

关联疾病

疾病名称 别名
Parkinson Disease, Late-Onset

Parkinson Disease

Parkinson'S Disease

PD

PARK

Parkinson Disease, Susceptibility To

Late Onset Parkinson'S Disease

Late Onset Parkinson Disease

Paralysis Agitans

Primary Parkinsonism

Idiopathic Parkinson Disease

Parkinson'S

Parkinson Disease, Late-Onset, Susceptibility To

Parkinson Disease, Age Of Onset, Modifier

Lewy Body Parkinson Disease

Idiopathic Parkinson'S Disease

Pd - [Parkinson Disease]

Parkinson Disease Nos

Parkinson, Nos

Primary Parkinson Disease

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta ZSCAN21 VGNC VGNC:81892
Bos taurus ZSCAN21 VGNC VGNC:37377
Canis familiaris ZSCAN21 VGNC VGNC:54101
Rattus norvegicus ZSCAN21 RGD RGD:1309981
Mus musculus ZSCAN21 MGD MGI:99182