1. Gene
  2. GSN - gelsolin Gene

GSN - gelsolin Gene

中文名称:凝溶胶蛋白

种属: Homo sapiens

同用名: ADF; AGEL

基因 ID: 2934 | 基因类型: protein coding

关于 GSN

Cytogenetic location: 9q33.2 Genomic coordinates (GRCh38): 9:121,201,483-121,332,842 (from NCBI)

This gene has 16 transcripts (splice variants), 271 orthologues, 7 paralogues and is associated with 3 phenotypes. Broad expression in fat (RPKM 444.2), heart (RPKM 172.6) and 23 other tissues.

功能概要

由该基因编码的蛋白质与肌动蛋白单体和丝的“加”端结合,以防止单体交换。编码的钙调节蛋白在肌动蛋白丝的组装和分解中起作用。该基因的缺陷是家族性淀粉样变性芬兰型 (FAF) 的一个原因。已发现该基因的多个转录变体编码几种不同的亚型。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

GSN 基因产物(36)

mRNA Protein Name
NM_000177.5 NP_000168.1 gelsolin isoform a precursor
NM_001127662.2 NP_001121134.1 gelsolin isoform b
NM_001127663.2 NP_001121135.2 gelsolin isoform f
NM_001127664.2 NP_001121136.1 gelsolin isoform b
NM_001127665.2 NP_001121137.1 gelsolin isoform b
NM_001127666.2 NP_001121138.1 gelsolin isoform c
NM_001127667.2 NP_001121139.1 gelsolin isoform c
NM_001258029.2 NP_001244958.1 gelsolin isoform d
NM_001258030.2 NP_001244959.1 gelsolin isoform e
NM_001353053.1 NP_001339982.1 gelsolin isoform b
NM_001353054.1 NP_001339983.1 gelsolin isoform b
NM_001353055.2 NP_001339984.1 gelsolin isoform b
NM_001353056.2 NP_001339985.1 gelsolin isoform b
NM_001353057.2 NP_001339986.1 gelsolin isoform b
NM_001353058.2 NP_001339987.1 gelsolin isoform b
NM_001353059.2 NP_001339988.1 gelsolin isoform b
NM_001353060.2 NP_001339989.1 gelsolin isoform b
NM_001353061.2 NP_001339990.1 gelsolin isoform b
NM_001353062.1 NP_001339991.1 gelsolin isoform b
NM_001353063.2 NP_001339992.1 gelsolin isoform c
NM_001353064.2 NP_001339993.1 gelsolin isoform c
NM_001353065.2 NP_001339994.1 gelsolin isoform c
NM_001353066.2 NP_001339995.1 gelsolin isoform c
NM_001353067.2 NP_001339996.1 gelsolin isoform c
NM_001353068.2 NP_001339997.1 gelsolin isoform c
NM_001353069.2 NP_001339998.1 gelsolin isoform c
NM_001353070.2 NP_001339999.1 gelsolin isoform c
NM_001353071.2 NP_001340000.1 gelsolin isoform c
NM_001353072.2 NP_001340001.1 gelsolin isoform c
NM_001353073.2 NP_001340002.1 gelsolin isoform c
NM_001353074.2 NP_001340003.1 gelsolin isoform c
NM_001353075.1 NP_001340004.1 gelsolin isoform c
NM_001353076.2 NP_001340005.1 gelsolin isoform g
NM_001353077.1 NP_001340006.1 gelsolin isoform c
NM_001353078.2 NP_001340007.1 gelsolin isoform h
NM_198252.3 NP_937895.1 gelsolin isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin binding IDA
IDA: 通过直接分析推断
18266911 GOA
enables calcium ion binding IMP
IMP: 通过突变表型推断
14596804 GOA
enables myosin II binding IPI
IPI: 通过物理相互作用推断
23325791 GOA
enables phosphatidylinositol 3-kinase catalytic subunit binding IPI
IPI: 通过物理相互作用推断
30568254 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
10793131 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in actin filament capping IMP
IMP: 通过突变表型推断
19666531 GOA
involved in actin filament depolymerization IDA
IDA: 通过直接分析推断
30568254 GOA
involved in actin filament organization IGI
IGI: 通过遗传相互作用推断
23575248 GOA
involved in actin filament polymerization IDA
IDA: 通过直接分析推断
3020431 GOA
involved in actin filament polymerization IMP
IMP: 通过突变表型推断
23729654 GOA
involved in actin filament severing IDA
IDA: 通过直接分析推断
3020431 GOA
involved in actin filament severing IMP
IMP: 通过突变表型推断
23575248 GOA
involved in amyloid fibril formation IMP
IMP: 通过突变表型推断
19904968 GOA
involved in cilium assembly IMP
IMP: 通过突变表型推断
20393563 GOA
NOT involved in extracellular matrix disassembly IMP
IMP: 通过突变表型推断
24236012 GOA
involved in hepatocyte apoptotic process IMP
IMP: 通过突变表型推断
22952982 GOA
involved in negative regulation of viral entry into host cell IMP
IMP: 通过突变表型推断
23575248 GOA
involved in positive regulation of actin nucleation IMP
IMP: 通过突变表型推断
19666531 GOA
involved in positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway IMP
IMP: 通过突变表型推断
22952982 GOA
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
22952982 GOA
involved in positive regulation of keratinocyte apoptotic process IMP
IMP: 通过突变表型推断
23729654 GOA
involved in protein destabilization IMP
IMP: 通过突变表型推断
19549824 GOA
involved in regulation of establishment of T cell polarity IMP
IMP: 通过突变表型推断
23575248 GOA
involved in regulation of plasma membrane raft polarization IMP
IMP: 通过突变表型推断
23575248 GOA
involved in regulation of podosome assembly IMP
IMP: 通过突变表型推断
24236012 GOA
involved in regulation of receptor clustering IMP
IMP: 通过突变表型推断
23575248 GOA
involved in renal protein absorption IMP
IMP: 通过突变表型推断
24601799 GOA
involved in sequestering of actin monomers IMP
IMP: 通过突变表型推断
19666531 GOA
involved in striated muscle atrophy IMP
IMP: 通过突变表型推断
19549824 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin cap IDA
IDA: 通过直接分析推断
23575248 GOA
colocalizes with cortical actin cytoskeleton IDA
IDA: 通过直接分析推断
23575248 GOA
located in cortical actin cytoskeleton IDA
IDA: 通过直接分析推断
24236012 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
23575248 GOA
located in cytosol IDA
IDA: 通过直接分析推断
3020431 GOA
located in extracellular region IDA
IDA: 通过直接分析推断
3020431 GOA
located in extracellular space IDA
IDA: 通过直接分析推断
14596804 GOA
colocalizes with nucleus IDA
IDA: 通过直接分析推断
23729654 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
23575248 GOA
located in podosome IDA
IDA: 通过直接分析推断
24236012 GOA
located in sarcoplasm IDA
IDA: 通过直接分析推断
19549824 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

GSN 蛋白结构

Gelsolin

Gelsolin: Gelsolin repeat (76 - 158)

Gelsolin

Gelsolin: Gelsolin repeat (198 - 270)

Gelsolin

Gelsolin: Gelsolin repeat (317 - 389)

Gelsolin

Gelsolin: Gelsolin repeat (455 - 536)

Gelsolin

Gelsolin: Gelsolin repeat (577 - 642)

Gelsolin

Gelsolin: Gelsolin repeat (681 - 757)

  • 0
  • 200
  • 400
  • 600
  • 782 a.a.
蛋白主名 其他名称

gelsolin

actin-depolymerizing factor

GSN 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra GSN P06396 DISC1 Homo sapiens Q9NRI5
Anti Tag CoIP
29961565
Cross GSN P06396 ACTA1 Oryctolagus cuniculus P68135
X-Ray Diffraction
19666512
Cross GSN P06396 ACTA1 Oryctolagus cuniculus P68135
GMS
19666512
Cross GSN P06396 ACTA1 Oryctolagus cuniculus P68135
IF
19666512
Cross GSN P06396 ACTA1 Oryctolagus cuniculus P68135
Far-WB
16531231
Cross GSN P06396 ACTA1 Oryctolagus cuniculus P68135
Polymerization
19666512
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Amyloidosis, Finnish Type

Finnish Type Amyloidosis

Meretoja Syndrome

Amyloidosis V

Amyloidosis, Meretoja Type

Amyloid Cranial Neuropathy With Lattice Corneal Dystrophy

Lattice Corneal Dystrophy Type Ii

Familial Amyloidosis, Finnish Type

Familial Amyloid Polyneuropathy Type Iv

Amyloidosis Due To Mutant Gelsolin

Agel Amyloidosis

Gelsolin Amyloidosis

Hereditary Gelsolin Amyloidosis

Lattice Corneal Dystrophy Type Ii Finnish

Gelsolin-Related Amyloidosis

Kymenlaakso Syndrome

Lattice Corneal Dystrophy, Gelsolin Type

Hereditary Amyloidosis, Finnish Type

Lattice Corneal Dystrophy Type 2

Amyloidosis 5

AMYL5

Agel

Familial Amyloidosis Finnish Type

Meretoja Type Amyloidosis

Type Iv Familial Amyloid Polyneuropathy

Familial Amyloid Polyneuropathy, Type V

Familial Amyloid Polyneuropathy, Type Iv

Amyloidosis

Amyloid Disease

Amyloid

Amyloid Degeneration

Amyloidosis Nos

Amyloid Deposition

Amyloid Infiltration

Idiopathic Amyloidosis

Hyaloid Degeneration

Lardaceous Degeneration

Lattice Corneal Dystrophy

Familial Amyloid Neuropathy, Finnish Type

Familial Amyloid Polyneuropathy, Type V

Hereditary Amyloidosis

Amyloidosis Hereditary

Familial Amyloidosis

Amyloidosis Familial

Amyloidosis, Hereditary

Amyloidosis, Familial

Genetic Amyloidosis

Heredofamilial Amyloidosis

Amyloidosis, Hereditary, Transthyretin-Related

Transthyretin Amyloidosis

Familial Amyloid Polyneuropathy

Ttr Amyloid Neuropathy

Transthyretin Amyloid Neuropathy

Transthyretin Amyloid Polyneuropathy

Fap

Familial Transthyretin Amyloidosis

Amyloidosis Transthyretin Related

Type I Familial Amyloid Polyneuropathy

Familial Amyloid Polyneuropathy Type I

Attrv122i Amyloidosis

Hereditary Amyloidosis, Transthyretin-Related

Amyloid Polyneuropathy, Familial

Attr Amyloidosis

Attrm Amyloidosis

Corino De Andrade'S Disease

Paramyloidosis

Transthyretin-Related Hereditary Amyloidosis

Ttr Amyloidosis

Hereditary Attr Amyloidosis

Portuguese Polyneuritic Amyloidosis

Portuguese Type Familial Amyloid Neuropathy

Swiss Type Amyloid Polyneuropathy

Type Ii Familial Amyloid Polyneuropathy

Attrv30m Amyloidosis

Attrv30m-Related Amyloidosis

Familial Amyloid Polyneuropathy, Portuguese-Swedish-Japanese Type

Attr Cardiomyopathy

Attrv122i-Related Amyloidosis

Ttr-Related Amyloid Cardiomyopathy

Ttr-Related Cardiac Amyloidosis

Transthyretin Amyloid Cardiopathy

Transthyretin-Related Familial Amyloid Cardiomyopathy

Amyloidosis, Transthyretin-Related

AMYL-TTR

Amyloidosis I

Amyloidosis Ohio Type

Amyloidosis Type 7

Amyloidosis Vii

Amyloid Polyneuropathy

Attr

Familial Amyloid Polyneuropathy Type Ii

Hereditary Amyloidosis Transthyretin-Related

Leptomeningeal Amyloidosis

Meningocerebrovascular Amyloidosis

Oculoleptomeningeal Amyloidosis

Familial Amyloid Polyneuropathies

Amyloidosis, Leptomeningeal

Senile Cardiac Amyloidosis

Amyloid Neuropathies, Familial

Danish Type Familial Amyloid Cardiomyopathy

Familial Amyloid Neuropathy, Portuguese Type

Amyloid Polyneuropathy, Swiss Type

Hereditary Oculoleptomeningeal Amyloid Angiopathy

Amyloid Neuropathies

Polyneuropathy

Polyneuropathies

Corneal Dystrophy, Gelatinous Drop-Like

Gelatinous Drop-Like Corneal Dystrophy

GDLD

Cdgdl

Corneal Amyloidosis

Lattice Corneal Dystrophy Type Iii

Amyloidosis, Corneal

Amyloid Corneal Dystrophy, Japanese Type

Gdcd

Primary Familial Amyloidosis Of The Cornea

Subepithelial Amyloidosis Of The Cornea

Corneal Dystrophy, Lattice Type 3

Corneal Dystrophy, Lattice Type Iii

Lattice Corneal Dystrophy, Type Iii

Amyloidosis Corneal

Lattice Corneal Dystrophy Type3

Amyloid Corneal Dystrophy Japanese Type

Dystrophy, Corneal, Gelatinous Drop-Like

Amyloid Of Cornea

Corneal Dystrophy
Amyloid Neuropathy

Amyloid Neuropathies

Neuropathy Amyloid

Corneal Dystrophy, Lattice Type I

Lattice Corneal Dystrophy Type I

Lcd1

CDL1

Lcd

Lattice Corneal Dystrophy Type 1

Corneal Dystrophy, Lattice Type 1

Biber-Haab-Dimmer Dystrophy

Lattice Corneal Dystrophy, Type I

Classic Lattice Corneal Dystrophy

Lcdi

Corneal Dystrophy Lattice Type I

Dystrophy, Corneal, Lattice Type I

Primary Cutaneous Amyloidosis

Plca

Primary Localized Cutaneous Amyloidosis

Familial Primary Localized Cutaneous Amyloidosis

Amyloidosis Ix

Lichen Amyloidosis Familial

Amyloidosis, Primary Cutaneous

Pca

Amyloidosis 9

Amyloidosis Familial Cutaneous Lichen

Fplca

Familial Lichen Amyloidosis

Amyloidosis, Familial Visceral

Ostertag Type Amyloidosis

German Type Amyloidosis

Familial Renal Amyloidosis

Amyloidosis Viii

Amyloidosis, 3 Or More Types

Familial Visceral Amyloidosis

Familial Amyloid Nephropathy

Hereditary Amyloid Nephropathy

Amyloidosis, Familial Renal

Amyloidosis, Systemic Nonneuropathic

Amyloidosis Familial Visceral

Amyloidosis 8

Amyloidosis, Ostertag Type

Hereditary Amyloidosis With Primary Renal Involvement

Hereditary Renal Amyloidosis

Renal Amyloidosis

Amyloidosis, Renal

Systemic Nonneuropathic Amyloidosis

Amyloidosis Familial Renal

Amyloidosis Systemic Nonneuropathic

Hereditary Amyloidosis With Primary Renal Involement

AMYL8

Systemic Non-Neuropathic Amyloidosis

Amyloid Nephropathy

Cerebral Amyloid Angiopathy, Cst3-Related

Cerebral Amyloid Angiopathy

Hereditary Cerebral Hemorrhage With Amyloidosis

Hchwa

Hereditary Cystatin C Amyloid Angiopathy

Cerebral Amyloid Angiopathy, Familial

Amyloidosis, Cerebroarterial, Icelandic Type

Amyloidosis Vi

Cerebral Hemorrhage, Hereditary, With Amyloidosis

Cst3-Related Cerebral Amyloid Angiopathy

Cerebral Hemorrhage, Hereditary, With Amyloidosis, Icelandic Variant

Hereditary Cerebral Hemorrhage With Amyloidosis, Icelandic Variant

Caa, Familial

Cerebral Amyloid Angiopathy, Genetic

Acys Amyloidosis

Cst3-Related Amyloidosis

Cystatin Amyloidosis

Hchwa, Icelandic Type

Hereditary Cerebral Hemorrhage With Amyloidosis, Icelandic Type

Amyloidosis 6

AMYL6

Acys

Caa

Cerebral Amyloid Angiopathy Cst3-Related

Cerebroarterial Amyloidosis Icelandic Type

Cystatin C Amyloidosis

Hccaa

Hchwai

Hchwa-I

Hereditary Cerebral Hemorrhage With Amyloidosis Icelandic Type

Cerebral Amyloid Angiopathy Familial

Angiopathy, Amyloid, Cerebral, Cst3-Related

Hereditary Cerebral Amyloid Angiopathy, Icelandic Type

Familial Cerebral Amyloid Angiopathy

Cerebral Amyloid Angiopathy, Hereditary

Corneal Disease

Corneal Diseases

Corneal Disorders

Cutis Laxa

Generalized Elastolysis

Loose Skin

Dermatolysis

Dermatomegaly

Cutis Laxa Syndrome

Keratoconus

Kc

Conical Cornea

Noninflammatory Corneal Thining

Bulging Cornea

Cornea Conical

Acquired Conus Of Cornea

Radial Neuropathy
Immunoglobulin Heavy Chain Amyloidosis

Ah Amyloidosis

Heavy Chain Amyloidosis

Amyloidosis Derived From Immunoglobulin Heavy Chain

Ig Heavy-Chain-Associated Amyloidosis

Blepharochalasis

Dermatolysis Palpebrarum

Adiposa Ptosis

Nephrotic Syndrome

Finnish Congenital Nephrotic Syndrome

Ns - [Nephrotic Syndrome]

Nephrosis Syndrome

Nephrosis Nos

Glomerular Lesion Nephrosis

Bladder Cancer

Urinary Bladder Cancer

Bladder Carcinoma

Urinary Bladder Carcinoma

Bladder Neoplasm

Bladder Tumor

Cancer, Bladder

Malignant Neoplasm Of Urinary Bladder

Carcinoma Of Bladder

Bladder Cancer, Somatic

Tumor Of The Bladder

Carcinoma Of Urinary Bladder

Bladder Carcinoma Urinary

Cancer Of The Urinary Bladder

Cancer, Urinary Bladder

Malignant Bladder Neoplasm

Malignant Bladder Tumor

Neoplasm Of The Bladder

Neoplasm Of The Urinary Bladder

Tumor Of The Urinary Bladder

Urinary Bladder Neoplasm

BLC

Urothelial Carcinoma Of The Bladder

Bladder Tumors

Urinary Bladder Neoplasms

Bladder Cancer Nos

Vesical Cancer Nos

Malignant Neoplasm Of Bladder, Part Unspecified

Malignant Tumour Of Urinary Bladder

Primary Malignant Neoplasm Of Bladder

Apolipoprotein A-Iv Associated Amyloidosis

Aapoaiv Amyloidosis

Renal Aapoaiv Amyloidosis

Apolipoprotein A-Iv Amyloidosis

Rheumatic Myocarditis

Acute Rheumatic Myocarditis

Active Rheumatic Fever With Myocarditis

Acute Rheumatic Carditis

Rheumatic Degeneration Of Myocardium

Rheumatic Fever With Myocarditis

Rheumatoid Myocarditis

Acute Rheumatic Heart Disease

Acute Rheumatic Fever With Myocarditis

Active Or Acute Rheumatic Myocarditis

Active Rheumatic Myocarditis

Active Rheumatic Progressive Myocarditis

Chronic Active Rheumatic Myocarditis

Old Active Rheumatic Myocarditis

Active Rheumatic Fibroid Myocarditis

Active Rheumatic Interstitial Myocarditis

Acute Or Subacute Rheumatic Myocardial Insufficiency

Acute Rheumatic Toxic Myocarditis

Inactive Or Quiescent Rheumatic Fever With Myocarditis

Inactive Rheumatic Myocarditis

Rheumatic Progressive Myocarditis

Rheumatic Fibroid Myocarditis

Rheumatic Interstitial Myocarditis

Myocardial Degeneration With Rheumatic Fever

Myocardial Insufficiency With Rheumatic Fever

Rheumatic Cardiomyopathy

Dilated Cardiomyopathy Due To Rheumatic Fever

Myocarditis Due To Rheumatic Fever

Rheumatic Myocardial Insufficiency

Tuberous Sclerosis

Tuberous Sclerosis Syndrome

Bourneville'S Disease

Epiloia

Cerebral Sclerosis

Tuberose Sclerosis

Tuberous Sclerosis 1

Bourneville Disease

Bourneville Phakomatosis

Pringle'S Disease

Epithelial-Stromal Tgfbi Dystrophy
Wild-Type Amyloidosis

Senile Systemic Amyloidosis

Attrwt Amyloidosis

Age Related Amyloidosis

Old Age Amyloidosis

Wild-Type Attr Amyloidosis

Wild-Type Transthyretin Cardiac Amyloidosis

Wild Type Attr Amyloidosis

Attrwt-Related Amyloidosis

Wild Type Attr-Related Amyloidosis

Renal Cell Carcinoma, Nonpapillary

Renal Cell Carcinoma

RCC

Nonpapillary Renal Cell Carcinoma

Clear Cell Renal Cell Carcinoma

Hypernephroma

Adenocarcinoma Of Kidney

Renal Carcinoma, Chromophobe, Somatic

Clear Cell Carcinoma Of Kidney

Clear-Cell Metastatic Renal Cell Carcinoma

Clear Cell Renal Carcinoma

Renal Cell Carcinoma, Somatic

Conventional Renal Cell Carcinoma

Conventional Renal Cell Carcinoma

Renal Clear Cell Carcinoma

Ccrcc

Hereditary Clear Cell Renal Cell Carcinoma

Carcinoma, Renal Cell

Renal Cell Carcinoma, Clear Cell, Somatic

Renal Cell Carcinoma, Clear Cell

Clear Cell Kidney Carcinoma

Clear Cell Rcc

Cystic-Multilocular Variant

Clear Cell Renal Cell Adenocarcinoma

Hereditary Clear Cell Renal Cell Adenocarcinoma

Common Renal Cell Carcinoma

Crcc

Renal Cell Carcinoma Non-Papillary

Carcinoma Renal Cell

Renal Cell Cancer

Carcinoma, Renal Cell, Nonpapillary

Cerebral Amyloid Angiopathy, App-Related

Hchwad

Amyloidosis, Cerebroarterial, App-Related

Amyloidosis, Hereditary, With Cerebral Hemorrhage, Dutch Variant

Cerebral Amyloid Angiopathy, App-Related, Dutch Variant

Cerebral Amyloid Angiopathy, App-Related, Iowa Variant

Cerebral Amyloid Angiopathy, App-Related, Italian Variant

Cerebral Amyloid Angiopathy, App-Related, Flemish Variant

Cerebral Amyloid Angiopathy, App-Related, Arctic Variant

Cerebral Amyloid Angiopathy, Dutch, Italian, Iowa, Flemish, Arctic Variants

App-Related Cerebral Amyloid Angiopathy

Abetaa21g Amyloidosis

Abeta Amyloidosis, Italian Type

Abeta Amyloidosis, Arctic Type

Abeta Amyloidosis, Iowa Type

Abeta Amyloidosis, Dutch Type

Hchwa-D

Abeta Amyloidosis, Flemish Type

Abetaa21g-Related Amyloidosis

Hchwa, Flemish Type

Hereditary Cerebral Hemorrhage With Amyloidosis, Flemish Type

Abetae22k Amyloidosis

Hchwa, Italian Type

Hereditary Cerebral Hemorrhage With Amyloidosis, Italian Type

Abetae22g Amyloidosis

Hchwa, Arctic Type

Hereditary Cerebral Hemorrhage With Amyloidosis, Arctic Type

Abetad23n Amyloidosis

Hchwa, Iowa Type

Hereditary Cerebral Hemorrhage With Amyloidosis, Iowa Type

Abetal34v Amyloidosis

Abeta Amyloidosis, Piedmont Type

Abetal34v-Related Amyloidosis

Hchwa, Piedmont Type

Hereditary Cerebral Hemorrhage With Amyloidosis, Piedmont Type

Abetae22q Amyloidosis

Hchwa, Dutch Type

Hereditary Cerebral Hemorrhage With Amyloidosis, Dutch Type

CAA-APP

Amyloidosis Cerebroarterial App-Related

Amyloidosis Hereditary With Cerebral Hemorrhage Dutch Variant

Cerebral Amyloid Angiopathy App-Related Arctic Variant

Cerebral Amyloid Angiopathy App-Related Dutch Variant

Cerebral Amyloid Angiopathy App-Related Flemish Variant

Cerebral Amyloid Angiopathy App-Related Iowa Variant

Cerebral Amyloid Angiopathy App-Related Italian Variant

Familial Occipital Calcifications With Hemorrhagic Strokes Leukoencephalopathy Arterial Dysplasia Dementia

Fochs-Ladd

Hereditary Cerebral Amyloid Angiopathy Dutch Type

Hereditary Cerebral Hemorrhage With Amyloidosis Dutch Type

Hereditary Cerebral Hemorrhage With Amyloidosis Italian Type

Cerebral Hemorrhage With Amyloidosis, Hereditary, Dutch Type

Immunoglobulin Light Chain Amyloidosis

Al Amyloidosis

Primary Amyloidosis

Primary Systemic Amyloidosis

Light Chain Amyloidosis

Amyloidosis Al

Amyloidosis Primary Systemic

Primary Al Amyloidosis

Primary Systemic Al Amyloidosis

Systemic Al Amyloidsis

Systemic Al Amyloidosis

Light-Chain Amyloidosis

Alys Amyloidosis

Familial Amyloid Nephropathy Due To Lysozyme Variant

Familial Renal Amyloidosis Due To Lysozyme Variant

Hereditary Amyloid Nephropathy Due To Lysozyme Variant

Hereditary Renal Amyloidosis Due To Lysozyme Variant

Lysozyme Amyloidosis

Amyloidosis Primary

Immunoglobulin Deposition Disease

Immunoglobulinic Amyloidosis

Amyloid Al

Recurrent Corneal Erosion

Recurrent Erosion Of Cornea

Recurrent Erosion Syndrome

Corneal Erosion

Non-Traumatic Recurrent Erosion Of Cornea

Asymmetric Motor Neuropathy
Cerebral Amyloid Angiopathy, Itm2b-Related, 1

Dementia, Familial British

Fbd

Presenile Dementia With Spastic Ataxia

Familial British Dementia

Abri Amyloidosis

Cerebral Amyloid Angiopathy, British Type

Itm2b-Related Cerebral Amyloid Angiopathy 1

Familial Dementia, British Type

Cerebral Amyloid Angiopathy, Itm2b-Related 1

CAA-ITM2B1

Cerebral Amyloid Angiopathy British Type

Dementia, Familial, British

Epithelial And Subepithelial Dystrophy
Cystic Fibrosis

Mucoviscidosis

CF

Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis

Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis

Cystic Fibrosis Lung Disease, Modifier Of

Cystic Fibrosis Of Pancreas

Fibrocystic Disease Of Pancreas

Cf - [Cystic Fibrosis]

Cystic Fibrosis Nos

Fibrocystic Disease

Fibrocystic Disease Of The Pancreas

Mucoviscidosis Of Pancreas

Nonproliferative Fibrocystic Disease

Pancreatic Cystic Fibrosis

Nerve Compression Syndrome

Entrapment Neuropathies

Compression Neuropathy

Entrapment Neuropathy

Peripheral Nerve Entrapment Syndrome

Nerve Compression Syndromes

Hereditary Liability To Pressure Palsies

Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Susceptibility To

Lung Cancer, Protection Against

Adenocarcinoma Of Lung, Somatic

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma

Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon

Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1

Alzheimer Disease, Familial, 1

Alzheimer Disease

Alzheimer'S Disease

Presenile And Senile Dementia

AD1

Alzheimer Disease, Susceptibility To

Alzheimer Disease, Late-Onset, Susceptibility To

Alzheimer Disease 1, Familial

AD

Familial Alzheimer Disease

Alzheimer Disease, Late-Onset

Alzheimers Dementia

Alzheimer Dementia

Alzheimer Sclerosis

Alzheimer Syndrome

Alzheimer-Type Dementia

Dat

Primary Senile Degenerative Dementia

Sdat

Alzheimer Disease 1

Autosomal Dominant Alzheimer Disease

Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy

Late Onset Alzheimer Disease

Alzheimers Disease

Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy

Late-Onset Alzheimers Disease

Alzheimer'S Disease Pathway Kegg

Dementia Due To Alzheimer'S Disease

Alzheimer Disease Type 1

Alzheimers

Myopathy

Muscular Diseases

Myopathies

Interstitial Lung Disease 2

Idiopathic Pulmonary Fibrosis

Ipf

Fibrocystic Pulmonary Dysplasia

Pulmonary Fibrosis, Idiopathic

Pulmonary Fibrosis, Idiopathic, Susceptibility To

Cryptogenic Fibrosing Alveolitis

ILD2

Idiopathic Pulmonary Fibrosis, Familial

Fibrosing Alveolitis, Cryptogenic

Uip

Fibrosing Alveolitis

Interstitial Pneumonitis, Usual

Familial Idiopathic Pulmonary Fibrosis

Idiopathic Fibrosing Alveolitis, Chronic Form

Usual Interstitial Pneumonia

Fibrosing Alveolitis Cryptogenic

Hamman-Rich Disease

Idiopathic Pulmonary Fibrosis Familial

Interstitial Pneumonitis Usual

Fibrosis Idiopathic Pulmonary

Fibrosis, Pulmonary, Idiopathic

Hamman-Rich Syndrome

Chronic Idiopathic Pulmonary Fibrosis

Acute Interstitial Pneumonia

Interstitial Pulmonary Fibrosis

Ipf - [Idiopathic Pulmonary Fibrosis]

Idiopathic Lung Fibrosis

Fibrosing Lung Disease

Pulmonary Fibrosis Nos

Fibrosing Pneumonitis

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus GSN VGNC VGNC:29680
Rattus norvegicus GSN RGD RGD:1303089
Canis familiaris GSN VGNC VGNC:41532
Macaca mulatta GSN VGNC VGNC:73299
Mus musculus GSN MGD MGI:95851
Felis catus GSN VGNC VGNC:67486