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  2. MYPOP - Myb related transcription factor, partner of profilin Gene

MYPOP - Myb related transcription factor, partner of profilin Gene

中文名称:Myb 相关转录因子,profilin 的伙伴

种属: Homo sapiens

同用名: P42pop

基因 ID: 339344 | 基因类型: protein coding

关于 MYPOP

Cytogenetic location: 19q13.32 Genomic coordinates (GRCh38): 19:45,890,023-45,902,613 (from NCBI)

This gene has 1 transcript (splice variant) and 93 orthologues. Ubiquitous expression in brain (RPKM 2.5), spleen (RPKM 2.4) and 25 other tissues.

功能概要

预测可实现 DNA 结合转录抑制活性、RNA 聚合酶 II 特异性和 RNA 聚合酶 II 顺式调节区序列特异性 DNA 结合活性。预计参与 RNA 聚合酶 II 对转录的负调控。预计活跃于核心。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

MYPOP 基因产物(1)

mRNA Protein Name
NM_001012643.4 NP_001012661.1 myb-related transcription factor, partner of profilin
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

MYPOP 蛋白结构

Myb_DNA-bind_5

Myb_DNA-bind_5: Myb/SANT-like DNA-binding domain (16 - 92)

  • 0
  • 100
  • 200
  • 300
  • 399 a.a.
蛋白主名 其他名称

myb-related transcription factor, partner of profilin

myb-related protein p42POP

MYPOP 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra MYPOP Q86VE0 KRT40 Homo sapiens Q6A162
Y2H Array
32296183
Intra MYPOP Q86VE0 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 KRTAP10-8 Homo sapiens P60410
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 KRTAP10-8 Homo sapiens P60410
Validated Y2H
32296183
Intra MYPOP Q86VE0 KRTAP10-8 Homo sapiens P60410
Y2H Array
32296183
Intra MYPOP Q86VE0 KRTAP10-9 Homo sapiens P60411
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 KRTAP10-9 Homo sapiens P60411
Y2H Array
32296183
Intra MYPOP Q86VE0 KRTAP10-7 Homo sapiens P60409
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 KRTAP10-7 Homo sapiens P60409
Y2H Array
32296183
Intra MYPOP Q86VE0 NECAB2 Homo sapiens Q7Z6G3-2
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 NECAB2 Homo sapiens Q7Z6G3-2
Y2H Array
32296183
Intra MYPOP Q86VE0 KRTAP12-2 Homo sapiens P59991
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 KRTAP12-2 Homo sapiens P59991
Y2H Array
32296183
Intra MYPOP Q86VE0 KRTAP5-6 Homo sapiens Q6L8G9
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 KRTAP5-6 Homo sapiens Q6L8G9
Y2H Array
32296183
Intra MYPOP Q86VE0 KRTAP19-5 Homo sapiens Q3LI72
Y2H Array
32296183
Intra MYPOP Q86VE0 KRTAP19-5 Homo sapiens Q3LI72
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 SYNCRIP Homo sapiens O60506-4
Y2H Array
32296183
Intra MYPOP Q86VE0 SYNCRIP Homo sapiens O60506-4
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
Intra MYPOP Q86VE0 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 KRTAP1-3 Homo sapiens Q8IUG1
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 KRTAP1-3 Homo sapiens Q8IUG1
Y2H Array
32296183
Intra MYPOP Q86VE0 RBPMS2 Homo sapiens Q6ZRY4
Y2H Array
32296183
Intra MYPOP Q86VE0 RBPMS2 Homo sapiens Q6ZRY4
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 RBMY1A1 Homo sapiens P0DJD3-2
Y2H Array
32296183
Intra MYPOP Q86VE0 RBMY1A1 Homo sapiens P0DJD3-2
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 KRTAP19-6 Homo sapiens Q3LI70
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 KRTAP19-6 Homo sapiens Q3LI70
Y2H Array
32296183
Intra MYPOP Q86VE0 CIB4 Homo sapiens A0PJX0
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 CIB4 Homo sapiens A0PJX0
Y2H Array
32296183
Intra MYPOP Q86VE0 BBC3 Homo sapiens Q96PG8
Y2H Array
32296183
Intra MYPOP Q86VE0 BBC3 Homo sapiens Q96PG8
Validated Y2H
32296183
Intra MYPOP Q86VE0 BBC3 Homo sapiens Q96PG8
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 NOTCH2NLC Homo sapiens P0DPK4
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 NOTCH2NLC Homo sapiens P0DPK4
Y2H Array
32296183
Intra MYPOP Q86VE0 TGM1 Homo sapiens P22735
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 TGM1 Homo sapiens P22735
Y2H Array
32296183
Intra MYPOP Q86VE0 PRR3 Homo sapiens P79522
Y2H Array
32296183
Intra MYPOP Q86VE0 PRR3 Homo sapiens P79522
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 BAG4 Homo sapiens O95429
Y2H Array
32296183
Intra MYPOP Q86VE0 BAG4 Homo sapiens O95429
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 RBM3 Homo sapiens P98179
Y2H Array
32296183
Intra MYPOP Q86VE0 RBM3 Homo sapiens P98179
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 HNRNPH1 Homo sapiens P31943
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 HNRNPH1 Homo sapiens P31943
Y2H Array
32296183
Intra MYPOP Q86VE0 AKAP8L Homo sapiens Q9ULX6
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 AKAP8L Homo sapiens Q9ULX6
Y2H Array
32296183
Intra MYPOP Q86VE0 AKAP8L Homo sapiens Q9ULX6
Validated Y2H
32296183
Intra MYPOP Q86VE0 CARD10 Homo sapiens Q9BWT7
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 CARD10 Homo sapiens Q9BWT7
Validated Y2H
32296183
Intra MYPOP Q86VE0 CARD10 Homo sapiens Q9BWT7
Y2H Array
32296183
Intra MYPOP Q86VE0 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra MYPOP Q86VE0 PRDM14 Homo sapiens Q9GZV8
Validated Y2H
32296183
Intra MYPOP Q86VE0 PRDM14 Homo sapiens Q9GZV8
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 PRDM14 Homo sapiens Q9GZV8
Y2H Array
32296183
Intra MYPOP Q86VE0 HNRNPK Homo sapiens P61978-2
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 HNRNPK Homo sapiens P61978-2
Y2H Array
32296183
Intra MYPOP Q86VE0 SAT1 Homo sapiens P21673
Y2H Array
32296183
Intra MYPOP Q86VE0 SAT1 Homo sapiens P21673
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 KHDRBS3 Homo sapiens O75525
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 KHDRBS3 Homo sapiens O75525
Y2H Array
32296183
Intra MYPOP Q86VE0 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 MDFI Homo sapiens Q99750
Validated Y2H
32296183
Intra MYPOP Q86VE0 MDFI Homo sapiens Q99750
Y2H Array
32296183
Intra MYPOP Q86VE0 TRA2B Homo sapiens P62995
Y2H Array
32296183
Intra MYPOP Q86VE0 TRA2B Homo sapiens P62995
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 HOXA1 Homo sapiens P49639
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 HOXA1 Homo sapiens P49639
Y2H Array
32296183
Intra MYPOP Q86VE0 FHL3 Homo sapiens Q13643
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 FHL3 Homo sapiens Q13643
Y2H Array
32296183
Intra MYPOP Q86VE0 CHIC2 Homo sapiens Q9UKJ5
Y2H Array
32296183
Intra MYPOP Q86VE0 CHIC2 Homo sapiens Q9UKJ5
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 CHIC2 Homo sapiens Q9UKJ5
Validated Y2H
32296183
Intra MYPOP Q86VE0 RBMX Homo sapiens P38159
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 RBMX Homo sapiens P38159
Y2H Array
32296183
Intra MYPOP Q86VE0 TNS2 Homo sapiens Q63HR2
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 KIFAP3 Homo sapiens Q92845
Y2H Prey Pooling
32296183
Intra MYPOP Q86VE0 KIFAP3 Homo sapiens Q92845
Validated Y2H
32296183
Intra MYPOP Q86VE0 KIFAP3 Homo sapiens Q92845
Y2H Array
32296183
Intra MYPOP Q86VE0 KRTAP3-1 Homo sapiens Q9BYR8
Validated Y2H
32296183
Intra MYPOP Q86VE0 KRTAP3-1 Homo sapiens Q9BYR8
Y2H Array
32296183
Intra MYPOP Q86VE0 KRTAP3-1 Homo sapiens Q9BYR8
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Myopathy, Centronuclear, 1

Autosomal Dominant Centronuclear Myopathy

CNM1

Centronuclear Myopathy 1

Ad-Cnm

Myopathy, Centronuclear, Autosomal Dominant

Myotubular Myopathy, Autosomal Dominant

Centronuclear Myopathy, Autosomal, Modifier Of

Autosomal Dominant Myotubular Myopathy

Dnm2-Related Centronuclear Myopathy

Centronuclear Myopathy Autosomal Dominant

Myopathies, Structural, Congenital

Myopathy, Centronuclear, Type 1

Neuronopathy, Distal Hereditary Motor, Type Iia

HMN2A

Hmn Iia

Neuropathy, Distal Hereditary Motor, Type Iia

Dhmn2a

Distal Hereditary Motor Neuronopathy Type 2a

Distal Hereditary Motor Neuropathy Type Iia

Neuronopathy, Distal Hereditary Motor, Type 2a

Spinal Muscular Atrophy, Distal, Adult, Autosomal Dominant, Iia

Charcot-Marie-Tooth Disease, Spinal, Iia

Autosomal Dominant Adult Spinal Muscular Atrophy Iia

Spinal Charcot-Marie-Tooth Disease Iia

Neuronopathy, Distal Hereditary Motor, 2a

Charcot-Marie-Tooth Disease Spinal Iia

Spinal Muscular Atrophy Distal Adult Autosomal Dominant Iia

Neuropathy, Motor, Distal, Hereditary, Type 2a

Nemaline Myopathy 11, Autosomal Recessive

NEM11

Nemaline Myopathy 11

Nemaline Myopathy 10

NEM10

Myopathy, Nemaline, Type 10

Carey-Fineman-Ziter Syndrome 1

Carey-Fineman-Ziter Syndrome

CFZS

Congenital Nonprogressive Myopathy With Moebius And Robin Sequences

Myopathy, Congenital Nonprogressive, With Moebius Sequence And Robin Sequence

Cfz Syndrome

Carey Fineman Ziter Syndrome

Myopathy, Congenital Nonprogressive With Moebius And Robin Sequences

Myopathy-Moebius-Robin Syndrome

CFZS1

Moebius Sequence, Robin Complex, And Hypotonia

Congenital Non-Progressive Myopathy With Moebius And Robin Sequences

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus MYPOP MGD MGI:2446472
Canis familiaris MYPOP VGNC VGNC:43587
Bos taurus MYPOP VGNC VGNC:58393
Rattus norvegicus MYPOP RGD RGD:1565160