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  2. RBM3 - RNA binding motif protein 3 Gene

RBM3 - RNA binding motif protein 3 Gene

中文名称:RNA 结合基序蛋白 3

种属: Homo sapiens

同用名: RNPL; IS1-RNPL

基因 ID: 5935 | 基因类型: protein coding

关于 RBM3

Cytogenetic location: Xp11.23 Genomic coordinates (GRCh38): X:48,574,484-48,581,162 (from NCBI)

This gene has 11 transcripts (splice variants), 168 orthologues and 36 paralogues. Ubiquitous expression in bone marrow (RPKM 49.3), fat (RPKM 41.3) and 25 other tissues.

功能概要

该基因是富含甘氨酸的 RNA 结合蛋白家族的一员,编码一种具有一个 RNA 识别基序 (RRM) 结构域的蛋白质。该基因的表达是由冷休克和低氧张力诱导的。 1 号染色体上存在一个假基因。预测编码不同亚型的多个可变剪接的转录物变体已经被表征,尽管其中一些变体符合无义介导的衰变 (NMD) 标准。[RefSeq 提供,2008 年 7 月]

This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2008]

RBM3 基因产物(1)

mRNA Protein Name
NM_006743.5 NP_006734.1 RNA-binding protein 3
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15518812 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

RBM3 蛋白结构

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (8 - 78)

  • 0
  • 100
  • 157 a.a.
蛋白主名 其他名称

RNA-binding protein 3

RNA binding motif (RNP1, RRM) protein 3

RBM3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra RBM3 P98179 CHTOP Homo sapiens Q9Y3Y2-3
Y2H Prey Pooling
32296183
Intra RBM3 P98179 CHTOP Homo sapiens Q9Y3Y2-3
Validated Y2H
32296183
Intra RBM3 P98179 CHTOP Homo sapiens Q9Y3Y2-3
Y2H Array
32296183
Intra RBM3 P98179 RBPMS2 Homo sapiens Q6ZRY4
Y2H Prey Pooling
32296183
Intra RBM3 P98179 RBPMS2 Homo sapiens Q6ZRY4
Validated Y2H
32296183
Intra RBM3 P98179 RBPMS2 Homo sapiens Q6ZRY4
Y2H Array
32296183
Intra RBM3 P98179 RBMY1A1 Homo sapiens P0DJD3-2
Y2H Prey Pooling
32296183
Intra RBM3 P98179 RBMY1A1 Homo sapiens P0DJD3-2
Y2H Array
32296183
Intra RBM3 P98179 PRR3 Homo sapiens P79522
Y2H Array
32296183
Intra RBM3 P98179 PRR3 Homo sapiens P79522
Y2H Prey Pooling
32296183
Intra RBM3 P98179 MYPOP Homo sapiens Q86VE0
Validated Y2H
32296183
Intra RBM3 P98179 HNRNPK Homo sapiens P61978
Validated Y2H
25416956
Intra RBM3 P98179 HNRNPK Homo sapiens P61978
Y2H Prey Pooling
25416956
Intra RBM3 P98179 HNRNPK Homo sapiens P61978
Anti Tag CoIP
35271311
Intra RBM3 P98179 SRSF3 Homo sapiens P84103
Y2H Prey Pooling
32296183
Intra RBM3 P98179 SRSF3 Homo sapiens P84103
Y2H Array
32296183
Intra RBM3 P98179 SNRPA Homo sapiens P09012
Y2H Prey Pooling
32296183
Intra RBM3 P98179 SNRPA Homo sapiens P09012
Y2H Array
31515488
Intra RBM3 P98179 SNRPA Homo sapiens P09012
Y2H Array
32296183
Intra RBM3 P98179 HNRNPK Homo sapiens P61978-2
Y2H Array
32296183
Intra RBM3 P98179 HNRNPK Homo sapiens P61978-2
Y2H Prey Pooling
32296183
Intra RBM3 P98179 KHDRBS3 Homo sapiens O75525
Y2H Prey Pooling
32296183
Intra RBM3 P98179 KHDRBS3 Homo sapiens O75525
Y2H Array
32296183
Intra RBM3 P98179 KHDRBS2 Homo sapiens Q5VWX1
Validated Y2H
25416956
Intra RBM3 P98179 KHDRBS2 Homo sapiens Q5VWX1
Validated Y2H
32296183
Intra RBM3 P98179 KHDRBS2 Homo sapiens Q5VWX1
Y2H Array
25416956
Intra RBM3 P98179 KHDRBS2 Homo sapiens Q5VWX1
Y2H Prey Pooling
32296183
Intra RBM3 P98179 KHDRBS2 Homo sapiens Q5VWX1
Y2H Array
32296183
Intra RBM3 P98179 KHDRBS2 Homo sapiens Q5VWX1
Y2H Array
31515488
Intra RBM3 P98179 RBMX Homo sapiens P38159
Y2H Prey Pooling
32296183
Intra RBM3 P98179 RBMX Homo sapiens P38159
Y2H Array
25416956
Intra RBM3 P98179 RBMX Homo sapiens P38159
Y2H Array
32296183
Intra RBM3 P98179 RBMX Homo sapiens P38159
Validated Y2H
25416956
Intra RBM3 P98179 RBMY1A1 Homo sapiens P0DJD3
Validated Y2H
25416956
Intra RBM3 P98179 RBMY1A1 Homo sapiens P0DJD3
Y2H Prey Pooling
25416956
Intra RBM3 P98179 RBMY1A1 Homo sapiens P0DJD3
Y2H Array
25416956
Intra RBM3 P98179 RBMY1F Homo sapiens Q15415
Y2H Prey Pooling
32296183
Intra RBM3 P98179 RBMY1F Homo sapiens Q15415
Validated Y2H
32296183
Intra RBM3 P98179 RBMY1F Homo sapiens Q15415
Y2H Array
25416956
Intra RBM3 P98179 RBMY1F Homo sapiens Q15415
Y2H Array
32296183
Intra RBM3 P98179 RBMY1F Homo sapiens Q15415
Y2H Prey Pooling
25416956
Intra RBM3 P98179 PCBP1 Homo sapiens Q15365
Validated Y2H
32296183
Cross RBM3 P98179 OPG127 Vaccinia virus P68318
Pull Down
15518812
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Testicular Malignant Germ Cell Cancer

Malignant Germ Cell Tumor Of Testis

Periampullary Adenocarcinoma
Testicular Germ Cell Cancer

Germ Cell Tumor Of Testis

Testicular Germ Cell Tumor

Testicular Germ Cell Neoplasm

Testicular Malignant Germ Cell Tumor

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris RBM3 VGNC VGNC:54837
Mus musculus RBM3 MGD MGI:1099460
Bos taurus RBM3 VGNC VGNC:52813
Rattus norvegicus RBM3 RGD RGD:620145
Others RBM3 NCBI