2. Gene
  3. RBMX - RNA binding motif protein X-linked Gene

RBMX - RNA binding motif protein X-linked Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：RNA 结合基序蛋白 X 连锁

种属: Homo sapiens

同用名: RNMX; HNRPG; HNRNPG; MRXS11; RBMXP1; RBMXRT; hnRNP-G

基因 ID: 27316 | 基因类型: protein coding

关于 RBMX

Cytogenetic location: Xq26.3 Genomic coordinates (GRCh38): X:136,869,192-136,880,725 (from NCBI)

This gene has 12 transcripts (splice variants), 70 orthologues, 36 paralogues and is associated with 1 phenotype. Ubiquitous expression in ovary (RPKM 77.9), lymph node (RPKM 53.8) and 25 other tissues.

功能概要

该基因属于 RBMY 基因家族，该家族包括候选 Y 染色体精子发生基因。该基因是 Y 染色体 RBMY 基因的活性 X 染色体同系物，广泛表达，而 RBMY 基因在精子发生中进化出雄性特异性功能。在 1、4、9、11 和 6 号染色体上发现的该基因的假基因可能是通过逆转录从原始基因衍生而来的。已经鉴定出编码不同亚型的选择性剪接转录物变体。在其中一个内含子中发现了一个 snoRNA 基因 (SNORD61) 。[RefSeq 提供，2009 年 9 月]

This gene belongs to the RBMY gene family which includes candidate Y chromosome spermatogenesis genes. This gene, an active X chromosome homolog of the Y chromosome RBMY gene, is widely expressed whereas the RBMY gene evolved a male-specific function in spermatogenesis. Pseudogenes of this gene, found on chromosomes 1, 4, 9, 11, and 6, were likely derived by retrotransposition from the original gene. Alternatively spliced transcript variants encoding different isoforms have been identified. A snoRNA gene (SNORD61) is found in one of its introns. [provided by RefSeq, Sep 2009]

RBMX 基因产物(2)

mRNA Protein Name
NM_001164803.2 NP_001158275.1 RNA-binding motif protein, X chromosome isoform 2
NM_002139.4 NP_002130.2 RNA-binding motif protein, X chromosome isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA binding IDA
IDA: 通过直接分析推断
21327109 GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
18541147 GOA
enables chromatin binding IDA
IDA: 通过直接分析推断
18541147 GOA
enables identical protein binding IDA
IDA: 通过直接分析推断
10749975 GOA
enables identical protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
enables mRNA binding IDA
IDA: 通过直接分析推断
12165565 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
10332027 GOA
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
10749975 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to interleukin-1 IDA
IDA: 通过直接分析推断
18445477 GOA
involved in membrane protein ectodomain proteolysis IDA
IDA: 通过直接分析推断
18445477 GOA
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
18541147 GOA
involved in regulation of alternative mRNA splicing, via spliceosome IDA
IDA: 通过直接分析推断
12165565 GOA
involved in transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
21327109 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of catalytic step 2 spliceosome IDA
IDA: 通过直接分析推断
11991638 GOA
located in euchromatin IDA
IDA: 通过直接分析推断
21327109 GOA
located in extracellular exosome IDA
IDA: 通过直接分析推断
18445477 GOA
located in nucleus IDA
IDA: 通过直接分析推断
10749975 GOA
part of protein-containing complex IDA
IDA: 通过直接分析推断
10749975 GOA
part of supraspliceosomal complex IDA
IDA: 通过直接分析推断
19282290 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RBMX 蛋白结构

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (10 - 80)

RBM1CTR

RBM1CTR: RBM1CTR (NUC064) family (173 - 217)

  • 0
  • 100
  • 200
  • 300
  • 391 a.a.
蛋白主名 其他名称

RNA-binding motif protein, X chromosome

glycoprotein p43

RBMX 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
RBMX P38159 ROBO3 Homo sapiens Q96HH0
Y2H Prey Pooling
25416956
种属内
RBMX P38159 ROBO3 Homo sapiens Q96HH0
Validated Y2H
25416956
种属内
RBMX P38159 PCDHB14 Homo sapiens Q9Y5E9
Validated Y2H
32296183
种属内
RBMX P38159 APOBEC3C Homo sapiens Q9NRW3
Validated Y2H
32296183
种属内
RBMX P38159 APOBEC3C Homo sapiens Q9NRW3
Y2H Prey Pooling
25416956
种属内
RBMX P38159 CMTM6 Homo sapiens Q9NX76
Y2H Prey Pooling
32296183
种属内
RBMX P38159 CMTM6 Homo sapiens Q9NX76
Validated Y2H
32296183
种属内
RBMX P38159 CMTM6 Homo sapiens Q9NX76
Y2H Array
32296183
种属内
RBMX P38159 RBMY1A1 Homo sapiens P0DJD3-2
Y2H Prey Pooling
32296183
种属内
RBMX P38159 RBMY1A1 Homo sapiens P0DJD3-2
Y2H Array
32296183
种属内
RBMX P38159 NYX Homo sapiens Q9GZU5
Validated Y2H
32296183
种属内
RBMX P38159 KHDRBS1 Homo sapiens Q07666
Anti Tag CoIP
35271311
种属内
RBMX P38159 PRPF31 Homo sapiens Q8WWY3
Validated Y2H
32296183
种属内
RBMX P38159 PRR3 Homo sapiens P79522
Validated Y2H
32296183
种属内
RBMX P38159 PRR3 Homo sapiens P79522
Y2H Array
25416956
种属内
RBMX P38159 MYPOP Homo sapiens Q86VE0
Validated Y2H
32296183
种属内
RBMX P38159 NABP1 Homo sapiens Q96AH0
Validated Y2H
32296183
种属内
RBMX P38159 RBM3 Homo sapiens P98179
Validated Y2H
32296183
种属内
RBMX P38159 RBM3 Homo sapiens P98179
Y2H Array
29892012
种属内
RBMX P38159 RBM3 Homo sapiens P98179
Y2H Prey Pooling
25416956
种属内
RBMX P38159 SRSF9 Homo sapiens Q13242
Y2H Prey Pooling
32296183
种属内
RBMX P38159 SRSF9 Homo sapiens Q13242
Validated Y2H
32296183
种属内
RBMX P38159 SRSF9 Homo sapiens Q13242
Y2H Array
32296183
种属内
RBMX P38159 SRSF9 Homo sapiens Q13242
Anti Tag CoIP
35271311
种属内
RBMX P38159 HNRNPK Homo sapiens P61978
Y2H Prey Pooling
25416956
种属内
RBMX P38159 HNRNPK Homo sapiens P61978
Y2H Array
25416956
种属内
RBMX P38159 HNRNPK Homo sapiens P61978
Y2H
21516116
种属内
RBMX P38159 HNRNPK Homo sapiens P61978
Validated Y2H
25416956
种属内
RBMX P38159 SRSF3 Homo sapiens P84103
Validated Y2H
32296183
种属内
RBMX P38159 SRSF3 Homo sapiens P84103
Y2H Prey Pooling
32296183
种属内
RBMX P38159 SRSF3 Homo sapiens P84103
Y2H Array
32296183
种属内
RBMX P38159 TARDBP Homo sapiens Q13148
Y2H Array
32814053
种属内
RBMX P38159 TARDBP Homo sapiens Q13148
Validated Y2H
32814053
种属内
RBMX P38159 TARDBP Homo sapiens Q13148
Y2H Pooling
32814053
种属内
RBMX P38159 FUS Homo sapiens P35637
Y2H
21988832
种属内
RBMX P38159 FUS Homo sapiens P35637
Anti Tag CoIP
35271311
种属内
RBMX P38159 CIRBP Homo sapiens Q14011
Validated Y2H
25416956
种属内
RBMX P38159 SNRPA Homo sapiens P09012
Validated Y2H
25416956
种属内
RBMX P38159 SNRPA Homo sapiens P09012
Y2H Array
25416956
种属内
RBMX P38159 HNRNPK Homo sapiens P61978-2
Validated Y2H
32296183
种属内
RBMX P38159 HNRNPK Homo sapiens P61978-2
Y2H Array
32296183
种属内
RBMX P38159 HNRNPK Homo sapiens P61978-2
Y2H Prey Pooling
32296183
种属内
RBMX P38159 HNRNPK Homo sapiens P61978-2
Complementation
32296183
种属内
RBMX P38159 KHDRBS3 Homo sapiens O75525
Y2H Prey Pooling
32296183
种属内
RBMX P38159 KHDRBS3 Homo sapiens O75525
Y2H Array
32296183
种属内
RBMX P38159 TRA2B Homo sapiens P62995
Y2H
22365833
种属内
RBMX P38159 TRA2B Homo sapiens P62995
Validated Y2H
32296183
种属内
RBMX P38159 TRA2B Homo sapiens P62995
Y2H Array
32296183
种属内
RBMX P38159 TRA2B Homo sapiens P62995
Y2H Prey Pooling
32296183
种属内
RBMX P38159 LNX1 Homo sapiens Q8TBB1
Y2H Pooling
16189514
种属内
RBMX P38159 LNX1 Homo sapiens Q8TBB1
Validated Y2H
32296183
种属内
RBMX P38159 CNNM3 Homo sapiens Q8NE01
Validated Y2H
32296183
种属内
RBMX P38159 KHDRBS2 Homo sapiens Q5VWX1
Validated Y2H
32296183
种属内
RBMX P38159 KHDRBS2 Homo sapiens Q5VWX1
Y2H Array
25416956
种属内
RBMX P38159 KHDRBS2 Homo sapiens Q5VWX1
BFG-2H
27107012
种属内
RBMX P38159 KHDRBS2 Homo sapiens Q5VWX1
Y2H Pooling
16189514
种属内
RBMX P38159 KHDRBS2 Homo sapiens Q5VWX1
Y2H Prey Pooling
25416956
种属内
RBMX P38159 KHDRBS2 Homo sapiens Q5VWX1
Validated Y2H
25416956
种属内
RBMX P38159 RBMX Homo sapiens P38159
Validated Y2H
32296183
种属内
RBMX P38159 RBMX Homo sapiens P38159
Y2H Array
25416956
种属内
RBMX P38159 RBMX Homo sapiens P38159
BFG-2H
27107012
种属内
RBMX P38159 RBMX Homo sapiens P38159
Y2H Array
32296183
种属内
RBMX P38159 RBMX Homo sapiens P38159
Anti Tag CoIP
35271311
种属内
RBMX P38159 RBMX Homo sapiens P38159
Validated Y2H
27107012
种属内
RBMX P38159 RBMX Homo sapiens P38159
Y2H Prey Pooling
32296183
种属内
RBMX P38159 CLK3 Homo sapiens P49761
Y2H Array
25416956
种属内
RBMX P38159 MAGOHB Homo sapiens Q96A72
Validated Y2H
25416956
种属内
RBMX P38159 RBMY1A1 Homo sapiens P0DJD3
Y2H Prey Pooling
25416956
种属内
RBMX P38159 RBMY1F Homo sapiens Q15415
Validated Y2H
32296183
种属内
RBMX P38159 RBMY1F Homo sapiens Q15415
Y2H Array
25416956
种属内
RBMX P38159 RBMY1F Homo sapiens Q15415
Y2H Array
32296183
种属内
RBMX P38159 RBMY1F Homo sapiens Q15415
Y2H Prey Pooling
32296183
种属间
RBMX P38159 Srek1 Rattus norvegicus Q9JKL7
Pull Down
14559993
种属间: 跨种属相互作用 种属内: 同种属相互作用

RBMX 抗体

目录号 产品名 应用 反应物种
HY-P83284 hnRNP G Antibody (YA3029) WB, IHC-F, IHC-P, ICC/IF Human

关联疾病

疾病名称 别名
Intellectual Developmental Disorder, X-Linked, Syndromic 11

MRXS11

Shashi X-Linked Mental Retardation Syndrome

Smrxs

X-Linked Intellectual Disability, Shashi Type

Mental Retardation, X-Linked, Shashi Type

Intellectual Developmental Disorder, X-Linked Syndromic 11, Shashi Type

Mental Retardation X-Linked Shashi Type

Syndromic X-Linked Intellectual Disability Type 11

Intellectual Developmental Disorder, Syndromic 11, Shashi Type
Syndromic X-Linked Intellectual Disability Shashi Type

Mental Retardation, X-Linked, Syndromic 11, Shashi Type

Mrxs11

Shashi X-Linked Mental Retardation Syndrome

Smrxs

Syndromic X-Linked Intellectual Disability Type 11

X-Linked Mental Retardation Shashi Type

Mental Retardation, X-Linked, Syndromic 11
Thrombophilia, X-Linked, Due To Factor Ix Defect

THPH8

Deep Venous Thrombosis, Protection Against

X-Linked Thrombophilia Due To Factor Ix Defect

Thrombophilia, X-Linked, Due To Factor 9 Defect

Thrombophilia 8, X-Linked, Due To Factor Ix Defect
Borna Disease

Enzootic Encephalomyelitis
Lissencephaly, X-Linked, 2

X-Linked Lissencephaly With Abnormal Genitalia

Hydranencephaly With Abnormal Genitalia

Xlag

Xlisg

X-Linked Lissencephaly With Ambiguous Genitalia

LISX2

Lissencephaly, X-Linked 2

X-Linked Lissencephaly 2

X-Linked Lissencephaly-Corpus Callosum Agenesis-Genital Anomalies Syndrome

Xlag Syndrome

Lissencephaly, X-Linked, With Ambiguous Genitalia

Xlis2

X-Linked Lissencephaly - Agenesis Of The Corpus Callosum - Genital Anomalies

X-Linked Lissencephaly-Agenesis Of The Corpus Callosum-Genital Anomalies Syndrome

Xlag Syndrome

Lissencephaly X-Linked With Ambiguous Genitalia

Lissencephaly, X-Linked, Type 2

Chromosome Xq26.3 Duplication Syndrome
Frontotemporal Dementia

Pallidopontonigral Degeneration

Frontotemporal Lobar Degeneration

Semantic Dementia

FTD

Frontotemporal Lobe Dementia

Multiple System Tauopathy With Presenile Dementia

Dementia, Frontotemporal

Frontotemporal Dementia With Parkinsonism

Mstd

Frontotemporal Lobar Degeneration With Tau Inclusions

Ftld With Tau Inclusions

Dementia, Frontotemporal, With Parkinsonism

Fldem

Ftdp17

Disinhibition-Dementia-Parkinsonism-Amyotrophy Complex

Ddpac

Wilhelmsen-Lynch Disease

Wld

Ppnd

Dementia, Frontotemporal, With Or Without Parkinsonism

Semantic Primary Progressive Aphasia

Semantic Variant Ppa

Wilhemsen-Lynch Disease

Frontotemporal Dementia-Amyotrophic Lateral Sclerosis

Frontotemporal Dementia And Parkinsonism Linked To Chromosome 17

Ftd-Als

Ftld

Pick Complex

Pick Disease Of The Brain

Frontotemporal Dementia With Parkinsonism-17

Grn-Related Frontotemporal Dementia

Frontotemporal Dementia With Motor Neuron Disease

Dementia In Fronto-Temporal Lobar Degeneration

Ftd - [Frontotemporal Dementia]

Temple Dementia

Frontal Lobe Dementia
X-Linked Hereditary Ataxia
Fragile X-Associated Tremor/Ataxia Syndrome

Fxtas Syndrome

Fragile X Tremor/Ataxia Syndrome

Fxtas
Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11763 RBMX Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus RBMX MGD MGI:1343044
Bos taurus RBMX VGNC VGNC:56951
Canis familiaris RBMX VGNC VGNC:54838
Rattus norvegicus RBMX RGD RGD:1565256
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