1. Gene
  2. KHDRBS2 - KH RNA binding domain containing, signal transduction associated 2 Gene

KHDRBS2 - KH RNA binding domain containing, signal transduction associated 2 Gene

中文名称:含 KH RNA 结合域,信号转导相关 2

种属: Homo sapiens

同用名: SLM1; SLM-1

基因 ID: 202559 | 基因类型: protein coding

关于 KHDRBS2

Cytogenetic location: 6q11.1 Genomic coordinates (GRCh38): 6:61,542,670-62,286,225 (from NCBI)

This gene has 2 transcripts (splice variants), 210 orthologues and 4 paralogues. Low expression observed in reference dataset.

功能概要

预测可实现 mRNA 结合活性和 poly (A) 结合活性。预计通过剪接体参与调节 mRNA 的选择性剪接。预测位于核质中。预计活跃于核心。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable mRNA binding activity and poly(A) binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

KHDRBS2 基因产物(2)

mRNA Protein Name
NM_001350622.2 NP_001337551.1 KH domain-containing, RNA-binding, signal transduction-associated protein 2 isoform 1
NM_152688.4 NP_689901.2 KH domain-containing, RNA-binding, signal transduction-associated protein 2 isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

KHDRBS2 蛋白结构

KH_1

KH_1: KH domain (63 - 104)

  • 0
  • 100
  • 200
  • 300
  • 349 a.a.
蛋白主名 其他名称

KH domain-containing, RNA-binding, signal transduction-associated protein 2

KH domain containing, RNA binding, signal transduction associated 2

KHDRBS2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra KHDRBS2 Q5VWX1 SULT1A3 Homo sapiens P0DMM9
Y2H Prey Pooling
25416956
Intra KHDRBS2 Q5VWX1 SULT1A3 Homo sapiens P0DMM9
Y2H Array
25416956
Intra KHDRBS2 Q5VWX1 ZNF497 Homo sapiens Q6ZNH5
Validated Y2H
32296183
Intra KHDRBS2 Q5VWX1 FOXD4L3 Homo sapiens Q6VB84
Validated Y2H
32296183
Intra KHDRBS2 Q5VWX1 ZNF837 Homo sapiens Q96EG3
Validated Y2H
32296183
Intra KHDRBS2 Q5VWX1 CHTOP Homo sapiens Q9Y3Y2-3
Validated Y2H
32296183
Intra KHDRBS2 Q5VWX1 LMNTD2 Homo sapiens Q8IXW0
Validated Y2H
32296183
Intra KHDRBS2 Q5VWX1 KHDRBS1 Homo sapiens Q07666
Anti Tag CoIP
33961781
Intra KHDRBS2 Q5VWX1 TYK2 Homo sapiens P29597
Validated Y2H
25416956
Intra KHDRBS2 Q5VWX1 TYK2 Homo sapiens P29597
Y2H Prey Pooling
25416956
Intra KHDRBS2 Q5VWX1 PTK6 Homo sapiens Q13882
Validated Y2H
25416956
Intra KHDRBS2 Q5VWX1 PRPF31 Homo sapiens Q8WWY3
Validated Y2H
27107012
Intra KHDRBS2 Q5VWX1 PRPF31 Homo sapiens Q8WWY3
Validated Y2H
25416956
Intra KHDRBS2 Q5VWX1 PRR3 Homo sapiens P79522
Y2H Array
25416956
Intra KHDRBS2 Q5VWX1 PRR3 Homo sapiens P79522
Y2H Prey Pooling
25416956
Intra KHDRBS2 Q5VWX1 YTHDC1 Homo sapiens Q96MU7
Y2H Array
25416956
Intra KHDRBS2 Q5VWX1 YTHDC1 Homo sapiens Q96MU7
Validated Y2H
32296183
Intra KHDRBS2 Q5VWX1 NABP1 Homo sapiens Q96AH0
Validated Y2H
25416956
Intra KHDRBS2 Q5VWX1 NABP1 Homo sapiens Q96AH0
Y2H Array
25416956
Intra KHDRBS2 Q5VWX1 RBM3 Homo sapiens P98179
Y2H Prey Pooling
25416956
Intra KHDRBS2 Q5VWX1 RBM3 Homo sapiens P98179
Y2H Array
29892012
Intra KHDRBS2 Q5VWX1 CHTOP Homo sapiens Q9Y3Y2
Y2H Array
25416956
Intra KHDRBS2 Q5VWX1 DOCK2 Homo sapiens Q92608
Validated Y2H
32296183
Intra KHDRBS2 Q5VWX1 CIRBP Homo sapiens Q14011
Validated Y2H
25416956
Intra KHDRBS2 Q5VWX1 CIRBP Homo sapiens Q14011
Y2H Prey Pooling
25416956
Intra KHDRBS2 Q5VWX1 ZFC3H1 Homo sapiens G3V1X1
Y2H Array
25416956
Intra KHDRBS2 Q5VWX1 ZFC3H1 Homo sapiens G3V1X1
Y2H Prey Pooling
25416956
Intra KHDRBS2 Q5VWX1 HNRNPR Homo sapiens O43390
Y2H Array
25416956
Intra KHDRBS2 Q5VWX1 MTA1 Homo sapiens Q13330
Y2H Prey Pooling
25416956
Intra KHDRBS2 Q5VWX1 MTA1 Homo sapiens Q13330
Validated Y2H
25416956
Intra KHDRBS2 Q5VWX1 SPG7 Homo sapiens Q9UQ90
Y2H Array
25416956
Intra KHDRBS2 Q5VWX1 HBZ Homo sapiens P02008
Validated Y2H
25416956
Intra KHDRBS2 Q5VWX1 KHDRBS3 Homo sapiens O75525
Y2H Array
32296183
Intra KHDRBS2 Q5VWX1 KHDRBS3 Homo sapiens O75525
Anti Tag CoIP
33961781
Intra KHDRBS2 Q5VWX1 KHDRBS3 Homo sapiens O75525
Y2H Prey Pooling
32296183
Intra KHDRBS2 Q5VWX1 SDCBP Homo sapiens O00560
Validated Y2H
25416956
Intra KHDRBS2 Q5VWX1 SDCBP Homo sapiens O00560
Y2H Prey Pooling
25416956
Intra KHDRBS2 Q5VWX1 LNX1 Homo sapiens Q8TBB1
Validated Y2H
32296183
Intra KHDRBS2 Q5VWX1 CNNM3 Homo sapiens Q8NE01
Validated Y2H
32296183
Intra KHDRBS2 Q5VWX1 TYMSOS Homo sapiens Q8TAI1
Validated Y2H
25416956
Intra KHDRBS2 Q5VWX1 BAHD1 Homo sapiens Q8TBE0
Validated Y2H
32296183
Intra KHDRBS2 Q5VWX1 RBMX Homo sapiens P38159
Pull Down
16189514
Intra KHDRBS2 Q5VWX1 RBMX Homo sapiens P38159
Y2H Prey Pooling
32296183
Intra KHDRBS2 Q5VWX1 RBMX Homo sapiens P38159
Y2H Array
32296183
Intra KHDRBS2 Q5VWX1 RBMX Homo sapiens P38159
Validated Y2H
27107012
Intra KHDRBS2 Q5VWX1 CATSPER1 Homo sapiens Q8NEC5
Validated Y2H
25416956
Intra KHDRBS2 Q5VWX1 CATSPER1 Homo sapiens Q8NEC5
Validated Y2H
32296183
Intra KHDRBS2 Q5VWX1 CATSPER1 Homo sapiens Q8NEC5
Y2H Array
25416956
Intra KHDRBS2 Q5VWX1 CATSPER1 Homo sapiens Q8NEC5
Y2H Prey Pooling
25416956
Intra KHDRBS2 Q5VWX1 ZNF581 Homo sapiens Q9P0T4
Validated Y2H
32296183
Intra KHDRBS2 Q5VWX1 NPDC1 Homo sapiens Q9NQX5
Validated Y2H
32296183
Intra KHDRBS2 Q5VWX1 NPDC1 Homo sapiens Q9NQX5
Validated Y2H
25416956
Intra KHDRBS2 Q5VWX1 AEN Homo sapiens Q8WTP8
Validated Y2H
25416956
Intra KHDRBS2 Q5VWX1 AEN Homo sapiens Q8WTP8
Y2H Array
25416956
Intra KHDRBS2 Q5VWX1 RBM14 Homo sapiens Q96PK6
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Canis familiaris KHDRBS2 VGNC VGNC:42336
Bos taurus KHDRBS2 VGNC VGNC:30541
Macaca mulatta KHDRBS2 VGNC VGNC:104409
Mus musculus KHDRBS2 MGD MGI:2159649
Rattus norvegicus KHDRBS2 RGD RGD:621738
Felis catus KHDRBS2 VGNC VGNC:102445