1. Gene
  2. REL - REL proto-oncogene, NF-kB subunit Gene

REL - REL proto-oncogene, NF-kB subunit Gene

中文名称:REL 原癌基因,NF-kB 亚单位

种属: Homo sapiens

同用名: C-Rel; IMD92; HIVEN86A

基因 ID: 5966 | 基因类型: protein coding

关于 REL

Cytogenetic location: 2p16.1 Genomic coordinates (GRCh38): 2:60,881,574-60,931,612 (from NCBI)

This gene has 8 transcripts (splice variants), 208 orthologues, 4 paralogues and is associated with 80 phenotypes. Ubiquitous expression in bone marrow (RPKM 13.2), appendix (RPKM 8.6) and 25 other tissues.

功能概要

该基因编码的蛋白质属于 Rel 同源域/免疫球蛋白样折叠、丛蛋白、转录因子 (RHD/IPT) 家族。这个家族的成员调节参与细胞凋亡、炎症、免疫反应和致癌过程的基因。这种原癌基因在 B 淋巴细胞的存活和增殖中发挥作用。该基因的突变或扩增与 B 细胞淋巴瘤有关,包括霍奇金淋巴瘤。该基因的单核苷酸多态性与溃疡性结肠炎和类风湿性关节炎的易感性有关。可变剪接导致编码不同异构体的多个转录变体。[RefSeq 提供,2014 年 4 月]

This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in Apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]

REL 基因产物(4)

mRNA Protein Name
XM_017004627.3 XP_016860116.1 proto-oncogene c-Rel isoform X1
XM_011533010.4 XP_011531312.1 proto-oncogene c-Rel isoform X2
NM_002908.4 NP_002899.1 proto-oncogene c-Rel isoform 1
NM_001291746.2 NP_001278675.1 proto-oncogene c-Rel isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
1406630 GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
1406630 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
10498867 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of gene expression IDA
IDA: 通过直接分析推断
22065573 GOA
involved in negative regulation of interferon-beta production IDA
IDA: 通过直接分析推断
22065573 GOA
involved in positive regulation of canonical NF-kappaB signal transduction IEP
IEP: 通过表达模式推断
12761501 GOA
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
1406630 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IMP
IMP: 通过突变表型推断
22065573 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

REL 蛋白结构

RHD_DNA_bind

RHD_DNA_bind: Rel homology DNA-binding domain (10 - 178)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 619 a.a.
蛋白主名 其他名称

proto-oncogene c-Rel

oncogene REL, avian reticuloendotheliosis

v-rel avian reticuloendotheliosis viral oncogene homolog

REL 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
REL Q04864 ZNF572 Homo sapiens Q7Z3I7
Validated Y2H
25416956
种属内
REL Q04864 ZNF572 Homo sapiens Q7Z3I7
Y2H Array
25416956
种属内
REL Q04864 NECAP1 Homo sapiens A8K3C2
Y2H Array
25416956
种属内
REL Q04864 NECAP1 Homo sapiens A8K3C2
Validated Y2H
25416956
种属内
REL Q04864 NECAP1 Homo sapiens A8K3C2
Y2H Prey Pooling
25416956
种属内
REL Q04864 b2r8y4_human Homo sapiens B2R8Y4
Y2H Array
25416956
种属内
REL Q04864 SEPTIN7 Homo sapiens Q16181-2
Validated Y2H
25416956
种属内
REL Q04864 SEPTIN7 Homo sapiens Q16181-2
Y2H Prey Pooling
25416956
种属内
REL Q04864 SEPTIN7 Homo sapiens Q16181-2
Y2H Array
25416956
种属内
REL Q04864 EPHB6 Homo sapiens O15197-2
Y2H Prey Pooling
25416956
种属内
REL Q04864 KRTAP9-4 Homo sapiens Q9BYQ2
Y2H Prey Pooling
25416956
种属内
REL Q04864 KRTAP9-4 Homo sapiens Q9BYQ2
Y2H Array
25416956
种属内
REL Q04864 HLA-DOA Homo sapiens P06340
Y2H Array
25416956
种属内
REL Q04864 HLA-DOA Homo sapiens P06340
Y2H Prey Pooling
25416956
种属内
REL Q04864 HLA-DOA Homo sapiens P06340
Validated Y2H
25416956
种属内
REL Q04864 CHAF1A Homo sapiens Q13111
Validated Y2H
25416956
种属内
REL Q04864 CHAF1A Homo sapiens Q13111
Y2H Array
25416956
种属内
REL Q04864 BID Homo sapiens P55957-2
Y2H Array
25416956
种属内
REL Q04864 BID Homo sapiens P55957-2
Y2H Prey Pooling
25416956
种属内
REL Q04864 MAP3K7CL Homo sapiens P57077-4
Validated Y2H
25416956
种属内
REL Q04864 MAP3K7CL Homo sapiens P57077-4
Y2H Array
25416956
种属内
REL Q04864 TTC21A Homo sapiens A0A0B4J1Y2
Y2H Array
25416956
种属内
REL Q04864 TTC21A Homo sapiens A0A0B4J1Y2
Validated Y2H
25416956
种属内
REL Q04864 RELA Homo sapiens Q04206-3
Y2H Prey Pooling
25416956
种属内
REL Q04864 RIPPLY1 Homo sapiens Q0D2K3
Validated Y2H
25416956
种属内
REL Q04864 PIH1D2 Homo sapiens Q8WWB5
Y2H Array
31515488
种属内
REL Q04864 PIH1D2 Homo sapiens Q8WWB5
Validated Y2H
25416956
种属内
REL Q04864 PTGER3 Homo sapiens P43115-12
Y2H Array
25416956
种属内
REL Q04864 PLEKHN1 Homo sapiens Q494U1
Y2H Array
31515488
种属内
REL Q04864 PLEKHN1 Homo sapiens Q494U1
Y2H Array
25416956
种属内
REL Q04864 RAB41 Homo sapiens Q5JT25
Validated Y2H
25416956
种属内
REL Q04864 SZT2 Homo sapiens Q5T011-5
Y2H Prey Pooling
25416956
种属内
REL Q04864 SZT2 Homo sapiens Q5T011-5
Y2H Array
25416956
种属内
REL Q04864 KLHL32 Homo sapiens Q5THT1
Y2H Prey Pooling
25416956
种属内
REL Q04864 KLHL32 Homo sapiens Q5THT1
Validated Y2H
25416956
种属内
REL Q04864 RECK Homo sapiens Q6P9E2
Validated Y2H
25416956
种属内
REL Q04864 RECK Homo sapiens Q6P9E2
Y2H Array
25416956
种属内
REL Q04864 RECK Homo sapiens Q6P9E2
Y2H Prey Pooling
25416956
种属内
REL Q04864 ZDHHC24 Homo sapiens Q6UX98
Y2H Array
25416956
种属内
REL Q04864 TRIM74 Homo sapiens Q86UV6-2
Validated Y2H
25416956
种属内
REL Q04864 NR2C2AP Homo sapiens Q86WQ0
Y2H Array
25416956
种属内
REL Q04864 NR2C2AP Homo sapiens Q86WQ0
Validated Y2H
25416956
种属内
REL Q04864 REXO1L1P Homo sapiens Q8IX06
Validated Y2H
25416956
种属内
REL Q04864 REXO1L1P Homo sapiens Q8IX06
Y2H Prey Pooling
25416956
种属内
REL Q04864 REXO1L1P Homo sapiens Q8IX06
Y2H Array
25416956
种属内
REL Q04864 ZNF564 Homo sapiens Q8TBZ8
Y2H Prey Pooling
25416956
种属内
REL Q04864 LGALS14 Homo sapiens Q8TCE9
Y2H Array
31515488
种属内
REL Q04864 LGALS14 Homo sapiens Q8TCE9
Y2H Prey Pooling
25416956
种属内
REL Q04864 HDAC7 Homo sapiens Q8WUI4-5
Y2H Array
25416956
种属内
REL Q04864 PATE1 Homo sapiens Q8WXA2
Y2H Prey Pooling
25416956
种属内
REL Q04864 NEIL2 Homo sapiens Q969S2
Y2H Array
25416956
种属内
REL Q04864 NEIL2 Homo sapiens Q969S2
Y2H Prey Pooling
25416956
种属内
REL Q04864 OAZ3 Homo sapiens Q9UMX2
Validated Y2H
25416956
种属内
REL Q04864 q96ba4_human Homo sapiens Q96BA4
Y2H Array
25416956
种属内
REL Q04864 q96ba4_human Homo sapiens Q96BA4
Y2H Prey Pooling
25416956
种属内
REL Q04864 SLC39A13 Homo sapiens Q96H72
Y2H Array
25416956
种属内
REL Q04864 CIB3 Homo sapiens Q96Q77
Y2H Prey Pooling
25416956
种属内
REL Q04864 CIB3 Homo sapiens Q96Q77
Validated Y2H
25416956
种属内
REL Q04864 NDUFAF3 Homo sapiens Q9BU61-2
Y2H Array
25416956
种属内
REL Q04864 NDUFAF3 Homo sapiens Q9BU61-2
Y2H Prey Pooling
25416956
种属内
REL Q04864 TXNL4B Homo sapiens Q9NX01
Y2H Prey Pooling
25416956
种属内
REL Q04864 TXNL4B Homo sapiens Q9NX01
Y2H Array
25416956
种属内
REL Q04864 PGAP6 Homo sapiens Q9HCN3
Validated Y2H
25416956
种属内
REL Q04864 PGAP6 Homo sapiens Q9HCN3
Y2H Array
25416956
种属内
REL Q04864 PGAP6 Homo sapiens Q9HCN3
Y2H Prey Pooling
25416956
种属内
REL Q04864 CABP5 Homo sapiens Q9NP86
Validated Y2H
25416956
种属内
REL Q04864 CABP5 Homo sapiens Q9NP86
Y2H Array
25416956
种属内
REL Q04864 NGB Homo sapiens Q9NPG2
Validated Y2H
25416956
种属内
REL Q04864 NGB Homo sapiens Q9NPG2
Y2H Array
25416956
种属内
REL Q04864 PRDM10 Homo sapiens Q9NQV6
Validated Y2H
25416956
种属内
REL Q04864 BARHL2 Homo sapiens Q9NY43
Validated Y2H
25416956
种属内
REL Q04864 BARHL2 Homo sapiens Q9NY43
Y2H Prey Pooling
25416956
种属内
REL Q04864 COL20A1 Homo sapiens Q9P218-2
Y2H Prey Pooling
25416956
种属内
REL Q04864 COL20A1 Homo sapiens Q9P218-2
Y2H Array
25416956
种属内
REL Q04864 SEC14L4 Homo sapiens Q9UDX3
Y2H Prey Pooling
25416956
种属内
REL Q04864 NEUROG3 Homo sapiens Q9Y4Z2
Y2H Prey Pooling
25416956
种属内
REL Q04864 NEUROG3 Homo sapiens Q9Y4Z2
Validated Y2H
25416956
种属内
REL Q04864 OSTF1 Homo sapiens Q92882
Validated Y2H
25416956
种属内
REL Q04864 OSTF1 Homo sapiens Q92882
Y2H Prey Pooling
25416956
种属内
REL Q04864 EML2 Homo sapiens O95834
Y2H Array
25416956
种属内
REL Q04864 EML2 Homo sapiens O95834
Validated Y2H
25416956
种属内
REL Q04864 EML2 Homo sapiens O95834
Y2H Prey Pooling
25416956
种属内
REL Q04864 MEMO1 Homo sapiens Q9Y316
Y2H Array
25416956
种属内
REL Q04864 ATPAF2 Homo sapiens Q8N5M1
Validated Y2H
25416956
种属内
REL Q04864 ATPAF2 Homo sapiens Q8N5M1
Y2H Prey Pooling
25416956
种属内
REL Q04864 ATPAF2 Homo sapiens Q8N5M1
Y2H Array
25416956
种属内
REL Q04864 EGLN3 Homo sapiens Q9H6Z9
Y2H Prey Pooling
25416956
种属内
REL Q04864 EGLN3 Homo sapiens Q9H6Z9
Y2H Array
25416956
种属内
REL Q04864 EGLN3 Homo sapiens Q9H6Z9
Validated Y2H
25416956
种属内
REL Q04864 DNTT Homo sapiens P04053
Validated Y2H
25416956
种属内
REL Q04864 DNTT Homo sapiens P04053
Y2H Prey Pooling
25416956
种属内
REL Q04864 ACOT8 Homo sapiens O14734
Y2H Prey Pooling
25416956
种属内
REL Q04864 ACOT8 Homo sapiens O14734
Validated Y2H
25416956
种属内
REL Q04864 PTK6 Homo sapiens Q13882
Validated Y2H
25416956
种属内
REL Q04864 PTK6 Homo sapiens Q13882
Y2H Array
25416956
种属内
REL Q04864 COMMD1 Homo sapiens Q8N668
Pull Down
15799966
种属内
REL Q04864 AGPAT4 Homo sapiens Q9NRZ5
Y2H Prey Pooling
25416956
种属内
REL Q04864 AGPAT4 Homo sapiens Q9NRZ5
Validated Y2H
25416956
种属内
REL Q04864 AGPAT4 Homo sapiens Q9NRZ5
Y2H Array
25416956
种属内
REL Q04864 SEC31A Homo sapiens O94979
Validated Y2H
25416956
种属内
REL Q04864 SEC31A Homo sapiens O94979
Y2H Prey Pooling
25416956
种属内
REL Q04864 UBASH3A Homo sapiens P57075
Y2H Prey Pooling
25416956
种属内
REL Q04864 UBASH3A Homo sapiens P57075
Validated Y2H
25416956
种属内
REL Q04864 NEDD9 Homo sapiens Q14511
Y2H Prey Pooling
25416956
种属内
REL Q04864 NEDD9 Homo sapiens Q14511
Validated Y2H
25416956
种属内
REL Q04864 CCNJL Homo sapiens Q8IV13
Y2H Prey Pooling
25416956
种属内
REL Q04864 CCNJL Homo sapiens Q8IV13
Y2H Array
25416956
种属内
REL Q04864 HAT1 Homo sapiens O14929
Validated Y2H
25416956
种属间
REL Q04864 P0DTD1-PRO_0000449631 SARS-CoV-2 P0DTD1-PRO_0000449631
Y2H Array
36217030
种属间
REL Q04864 P0DTD1-PRO_0000449633 SARS-CoV-2 P0DTD1-PRO_0000449633
Y2H Array
36217030
种属内
REL Q04864 DYNC1LI1 Homo sapiens Q9Y6G9
Y2H Array
31515488
种属内
REL Q04864 DYNC1LI1 Homo sapiens Q9Y6G9
Y2H Prey Pooling
25416956
种属内
REL Q04864 ASAP3 Homo sapiens Q8TDY4
Y2H Prey Pooling
25416956
种属内
REL Q04864 LNPEP Homo sapiens Q9UIQ6
Validated Y2H
25416956
种属内
REL Q04864 LNPEP Homo sapiens Q9UIQ6
Y2H Array
25416956
种属内
REL Q04864 RELA Homo sapiens Q04206-2
TAP
14743216
种属内
REL Q04864 RELA Homo sapiens Q04206-2
Anti Tag CoIP
28514442
种属内
REL Q04864 FUT11 Homo sapiens Q495W5
Validated Y2H
25416956
种属内
REL Q04864 FUT11 Homo sapiens Q495W5
Y2H Prey Pooling
25416956
种属内
REL Q04864 FUT11 Homo sapiens Q495W5
Y2H Array
25416956
种属内
REL Q04864 C9orf72 Homo sapiens Q96LT7
Y2H Array
25416956
种属内
REL Q04864 NFKB2 Homo sapiens Q00653
Anti Tag CoIP
33961781
种属内
REL Q04864 NFKB2 Homo sapiens Q00653
Anti Tag CoIP
28514442
种属内
REL Q04864 NFKB2 Homo sapiens Q00653
TAP
14743216
种属内
REL Q04864 NFKBIA Homo sapiens P25963
TAP
14743216
种属内
REL Q04864 NFKBIA Homo sapiens P25963
Anti Tag CoIP
33961781
种属内
REL Q04864 LSM2 Homo sapiens Q9Y333
Validated Y2H
25416956
种属内
REL Q04864 LSM2 Homo sapiens Q9Y333
Y2H Array
25416956
种属内
REL Q04864 NFKBIB Homo sapiens Q15653
TAP
14743216
种属内
REL Q04864 EIF3D Homo sapiens O15371
Validated Y2H
25416956
种属内
REL Q04864 NFKBIE Homo sapiens O00221
Anti Tag CoIP
33961781
种属内
REL Q04864 NFKBIE Homo sapiens O00221
Anti Tag CoIP
28514442
种属内
REL Q04864 PSMA1 Homo sapiens P25786
Y2H Array
25416956
种属内
REL Q04864 PSMA1 Homo sapiens P25786
Y2H Prey Pooling
25416956
种属内
REL Q04864 PSMA1 Homo sapiens P25786
Validated Y2H
25416956
种属内
REL Q04864 TNIP2 Homo sapiens Q8NFZ5
Anti Tag CoIP
33961781
种属内
REL Q04864 TNIP2 Homo sapiens Q8NFZ5
Anti Tag CoIP
28514442
种属内
REL Q04864 POLR2L Homo sapiens P62875
Y2H Array
25416956
种属内
REL Q04864 POLR2L Homo sapiens P62875
Validated Y2H
25416956
种属内
REL Q04864 POP5 Homo sapiens Q969H6
Y2H Prey Pooling
25416956
种属内
REL Q04864 RASSF5 Homo sapiens Q8WWW0
Y2H Prey Pooling
25416956
种属内
REL Q04864 RASSF5 Homo sapiens Q8WWW0
Y2H Array
25416956
种属内
REL Q04864 EXOSC5 Homo sapiens Q9NQT4
Y2H Array
25416956
种属内
REL Q04864 EXOSC5 Homo sapiens Q9NQT4
Y2H Prey Pooling
25416956
种属内
REL Q04864 EXOSC1 Homo sapiens Q9Y3B2
Validated Y2H
25416956
种属内
REL Q04864 EXOSC1 Homo sapiens Q9Y3B2
Y2H Prey Pooling
25416956
种属内
REL Q04864 EXOSC1 Homo sapiens Q9Y3B2
Y2H Array
25416956
种属内
REL Q04864 EXOSC1 Homo sapiens Q9Y3B2
Y2H Array
31515488
种属内
REL Q04864 EXOSC8 Homo sapiens Q96B26
Validated Y2H
25416956
种属内
REL Q04864 EXOSC8 Homo sapiens Q96B26
Y2H Array
25416956
种属内
REL Q04864 EXOSC8 Homo sapiens Q96B26
Y2H Prey Pooling
25416956
种属内
REL Q04864 NAGK Homo sapiens Q9UJ70
Y2H Prey Pooling
25416956
种属内
REL Q04864 EIF5A Homo sapiens P63241
Y2H Array
25416956
种属内
REL Q04864 BMF Homo sapiens Q96LC9
Y2H Prey Pooling
25416956
种属内
REL Q04864 PARVG Homo sapiens Q9HBI0
Y2H Prey Pooling
25416956
种属内
REL Q04864 PARVG Homo sapiens Q9HBI0
Y2H Array
25416956
种属内
REL Q04864 PARVG Homo sapiens Q9HBI0
Validated Y2H
25416956
种属内
REL Q04864 EIF4E2 Homo sapiens O60573
Y2H Prey Pooling
25416956
种属内
REL Q04864 EIF4E2 Homo sapiens O60573
Validated Y2H
25416956
种属内
REL Q04864 EIF4E2 Homo sapiens O60573
Y2H Array
25416956
种属内
REL Q04864 MORF4L1 Homo sapiens Q9UBU8
Y2H Prey Pooling
25416956
种属内
REL Q04864 MORF4L1 Homo sapiens Q9UBU8
Validated Y2H
25416956
种属内
REL Q04864 MORF4L1 Homo sapiens Q9UBU8
Y2H Array
25416956
种属内
REL Q04864 GRB2 Homo sapiens P62993
Validated Y2H
25416956
种属内
REL Q04864 GRB2 Homo sapiens P62993
Y2H Array
25416956
种属内
REL Q04864 GRB2 Homo sapiens P62993
Y2H Prey Pooling
25416956
种属内
REL Q04864 FOXO4 Homo sapiens P98177
Y2H Array
25416956
种属内
REL Q04864 GADD45G Homo sapiens O95257
Y2H Array
31515488
种属内
REL Q04864 GADD45G Homo sapiens O95257
Y2H Prey Pooling
25416956
种属内
REL Q04864 GADD45G Homo sapiens O95257
Validated Y2H
25416956
种属内
REL Q04864 GADD45G Homo sapiens O95257
Y2H Array
25416956
种属内
REL Q04864 CKS1B Homo sapiens P61024
Y2H Array
25416956
种属内
REL Q04864 CKS1B Homo sapiens P61024
Y2H Prey Pooling
25416956
种属内
REL Q04864 CKS1B Homo sapiens P61024
Validated Y2H
25416956
种属内
REL Q04864 IL36RN Homo sapiens Q9UBH0
Y2H Prey Pooling
25416956
种属内
REL Q04864 IL36RN Homo sapiens Q9UBH0
Validated Y2H
25416956
种属内
REL Q04864 UBE2K Homo sapiens P61086
Y2H Array
25416956
种属内
REL Q04864 HIP1 Homo sapiens O00291
Validated Y2H
25416956
种属内
REL Q04864 HIP1 Homo sapiens O00291
Y2H Prey Pooling
25416956
种属内
REL Q04864 HIP1 Homo sapiens O00291
Y2H Array
25416956
种属内
REL Q04864 BID Homo sapiens P55957
Y2H Prey Pooling
25416956
种属内
REL Q04864 BID Homo sapiens P55957
Validated Y2H
25416956
种属内
REL Q04864 BID Homo sapiens P55957
Y2H Array
25416956
种属内
REL Q04864 NUDT14 Homo sapiens O95848
Y2H Prey Pooling
25416956
种属内
REL Q04864 NUDT14 Homo sapiens O95848
Y2H Array
25416956
种属内
REL Q04864 MIEN1 Homo sapiens Q9BRT3
Y2H Array
25416956
种属内
REL Q04864 EPM2AIP1 Homo sapiens Q7L775
Validated Y2H
25416956
种属内
REL Q04864 EPM2AIP1 Homo sapiens Q7L775
Y2H Prey Pooling
25416956
种属内
REL Q04864 RBM39 Homo sapiens Q14498-3
Y2H Prey Pooling
25416956
种属内
REL Q04864 RBM39 Homo sapiens Q14498-3
Y2H Array
25416956
种属内
REL Q04864 FKBP1B Homo sapiens P68106
Y2H Prey Pooling
25416956
种属内
REL Q04864 FKBP1B Homo sapiens P68106
Validated Y2H
25416956
种属内
REL Q04864 FHL2 Homo sapiens Q14192
Y2H Prey Pooling
25416956
种属内
REL Q04864 FHL2 Homo sapiens Q14192
Y2H Array
25416956
种属内
REL Q04864 CPNE2 Homo sapiens Q96FN4
Y2H Prey Pooling
25416956
种属内
REL Q04864 CPNE2 Homo sapiens Q96FN4
Validated Y2H
25416956
种属内
REL Q04864 ARIH2 Homo sapiens O95376
Y2H Prey Pooling
25416956
种属内
REL Q04864 ARIH2 Homo sapiens O95376
Validated Y2H
25416956
种属内
REL Q04864 CDKN2C Homo sapiens P42773
Y2H Array
31515488
种属内
REL Q04864 CDKN2C Homo sapiens P42773
Y2H Prey Pooling
25416956
种属内
REL Q04864 CDKN2C Homo sapiens P42773
Validated Y2H
25416956
种属内
REL Q04864 SAT1 Homo sapiens P21673
Y2H Prey Pooling
25416956
种属内
REL Q04864 SAT1 Homo sapiens P21673
Validated Y2H
25416956
种属内
REL Q04864 SAT1 Homo sapiens P21673
Y2H Array
25416956
种属内
REL Q04864 NCK2 Homo sapiens O43639
Y2H Prey Pooling
25416956
种属内
REL Q04864 POLE2 Homo sapiens P56282
Validated Y2H
25416956
种属内
REL Q04864 POLE2 Homo sapiens P56282
Y2H Array
25416956
种属内
REL Q04864 RABIF Homo sapiens P47224
Y2H Prey Pooling
25416956
种属内
REL Q04864 RABIF Homo sapiens P47224
Validated Y2H
25416956
种属内
REL Q04864 RABIF Homo sapiens P47224
Y2H Array
25416956
种属内
REL Q04864 TSSC4 Homo sapiens Q9Y5U2
Y2H Prey Pooling
25416956
种属内
REL Q04864 TSSC4 Homo sapiens Q9Y5U2
Validated Y2H
25416956
种属内
REL Q04864 TSSC4 Homo sapiens Q9Y5U2
Y2H Array
25416956
种属内
REL Q04864 TLE5 Homo sapiens Q08117
Validated Y2H
25416956
种属内
REL Q04864 TLE5 Homo sapiens Q08117
Y2H Prey Pooling
25416956
种属内
REL Q04864 UBE2Z Homo sapiens Q9H832
Validated Y2H
25416956
种属内
REL Q04864 C11orf68 Homo sapiens Q9H3H3
Y2H Array
25416956
种属内
REL Q04864 C11orf68 Homo sapiens Q9H3H3
Validated Y2H
25416956
种属内
REL Q04864 SLC41A3 Homo sapiens Q96GZ6
Validated Y2H
25416956
种属内
REL Q04864 SLC41A3 Homo sapiens Q96GZ6
Y2H Array
25416956
种属内
REL Q04864 CGGBP1 Homo sapiens Q9UFW8
Y2H Array
25416956
种属内
REL Q04864 CGGBP1 Homo sapiens Q9UFW8
Y2H Array
29892012
种属内
REL Q04864 MRPL10 Homo sapiens Q7Z7H8
Y2H Array
25416956
种属内
REL Q04864 SDCBP Homo sapiens O00560
Validated Y2H
25416956
种属内
REL Q04864 SDCBP Homo sapiens O00560
Y2H Prey Pooling
25416956
种属内
REL Q04864 ATG9A Homo sapiens Q7Z3C6
Y2H Array
25416956
种属内
REL Q04864 ATG9A Homo sapiens Q7Z3C6
Y2H Prey Pooling
25416956
种属内
REL Q04864 RELA Homo sapiens Q04206
Anti Tag CoIP
33961781
种属内
REL Q04864 RELA Homo sapiens Q04206
Y2H
10498867
种属内
REL Q04864 HSPB7 Homo sapiens Q9UBY9
Validated Y2H
25416956
种属内
REL Q04864 LMO2 Homo sapiens P25791
Validated Y2H
25416956
种属内
REL Q04864 LMO2 Homo sapiens P25791
Y2H Array
25416956
种属内
REL Q04864 ZNF417 Homo sapiens Q8TAU3
Y2H Prey Pooling
25416956
种属内
REL Q04864 EIF4EBP1 Homo sapiens Q13541
Validated Y2H
25416956
种属内
REL Q04864 EIF4EBP1 Homo sapiens Q13541
Y2H Array
25416956
种属内
REL Q04864 EIF4EBP1 Homo sapiens Q13541
Y2H Prey Pooling
25416956
种属内
REL Q04864 CEP19 Homo sapiens Q96LK0
Validated Y2H
25416956
种属内
REL Q04864 CEP19 Homo sapiens Q96LK0
Y2H Array
25416956
种属内
REL Q04864 CEP19 Homo sapiens Q96LK0
Y2H Prey Pooling
25416956
种属内
REL Q04864 DHPS Homo sapiens P49366
Validated Y2H
25416956
种属内
REL Q04864 DHPS Homo sapiens P49366
Y2H Array
25416956
种属内
REL Q04864 VPS25 Homo sapiens Q9BRG1
Y2H Prey Pooling
25416956
种属内
REL Q04864 VPS25 Homo sapiens Q9BRG1
Y2H Array
25416956
种属内
REL Q04864 VPS25 Homo sapiens Q9BRG1
Y2H Array
29892012
种属内
REL Q04864 FLAD1 Homo sapiens Q8NFF5
Y2H Prey Pooling
25416956
种属内
REL Q04864 LASP1 Homo sapiens Q14847
Y2H Array
25416956
种属内
REL Q04864 LASP1 Homo sapiens Q14847
Validated Y2H
25416956
种属内
REL Q04864 EFHC1 Homo sapiens Q5JVL4
Y2H Array
25416956
种属内
REL Q04864 EFHC1 Homo sapiens Q5JVL4
Y2H Array
31515488
种属内
REL Q04864 EFHC1 Homo sapiens Q5JVL4
Y2H Prey Pooling
25416956
种属内
REL Q04864 NME7 Homo sapiens Q9Y5B8
Validated Y2H
25416956
种属内
REL Q04864 OTUB2 Homo sapiens Q96DC9
Y2H Prey Pooling
25416956
种属内
REL Q04864 MAGOHB Homo sapiens Q96A72
Validated Y2H
25416956
种属内
REL Q04864 MAGOHB Homo sapiens Q96A72
Y2H Array
25416956
种属内
REL Q04864 CTNNBIP1 Homo sapiens Q9NSA3
Y2H Prey Pooling
25416956
种属内
REL Q04864 COL8A1 Homo sapiens P27658
Validated Y2H
25416956
种属内
REL Q04864 COL8A1 Homo sapiens P27658
Y2H Array
25416956
种属内
REL Q04864 COL8A1 Homo sapiens P27658
Y2H Prey Pooling
25416956
种属内
REL Q04864 TRAPPC2L Homo sapiens Q9UL33
Validated Y2H
25416956
种属内
REL Q04864 EIF5A2 Homo sapiens Q9GZV4
Y2H Prey Pooling
25416956
种属内
REL Q04864 RSPH14 Homo sapiens Q9UHP6
Y2H Array
25416956
种属内
REL Q04864 GLYCTK Homo sapiens Q8IVS8
Y2H Prey Pooling
25416956
种属内
REL Q04864 GLYCTK Homo sapiens Q8IVS8
Validated Y2H
25416956
种属内
REL Q04864 GLYCTK Homo sapiens Q8IVS8
Y2H Array
25416956
种属内
REL Q04864 STK16 Homo sapiens O75716
Y2H Array
25416956
种属内
REL Q04864 NXT2 Homo sapiens Q9NPJ8
Y2H Prey Pooling
25416956
种属内
REL Q04864 NXT2 Homo sapiens Q9NPJ8
Y2H Array
25416956
种属内
REL Q04864 MAD2L2 Homo sapiens Q9UI95
Validated Y2H
25416956
种属内
REL Q04864 ALOX5 Homo sapiens P09917
Validated Y2H
25416956
种属内
REL Q04864 LMO1 Homo sapiens P25800
Y2H Array
25416956
种属内
REL Q04864 TSTD2 Homo sapiens Q5T7W7
Y2H Prey Pooling
25416956
种属内
REL Q04864 TSTD2 Homo sapiens Q5T7W7
Y2H Array
25416956
种属内
REL Q04864 OSGIN1 Homo sapiens Q9UJX0
Validated Y2H
25416956
种属内
REL Q04864 OSGIN1 Homo sapiens Q9UJX0
Y2H Prey Pooling
25416956
种属内
REL Q04864 ATXN1 Homo sapiens P54253
Y2H Prey Pooling
25416956
种属内
REL Q04864 TTC19 Homo sapiens Q6DKK2
Y2H Array
25416956
种属内
REL Q04864 FLNA Homo sapiens P21333-2
Y2H Array
25416956
种属内
REL Q04864 SNRNP25 Homo sapiens Q9BV90
Y2H Prey Pooling
25416956
种属内
REL Q04864 SNRNP25 Homo sapiens Q9BV90
Y2H Array
25416956
种属内
REL Q04864 ZNF765 Homo sapiens Q7L2R6
Y2H Array
25416956
种属内
REL Q04864 DMRT3 Homo sapiens Q9NQL9
Y2H Array
25416956
种属内
REL Q04864 DMRT3 Homo sapiens Q9NQL9
Y2H Prey Pooling
25416956
种属内
REL Q04864 PLCB4 Homo sapiens Q15147
Validated Y2H
25416956
种属内
REL Q04864 PLCB4 Homo sapiens Q15147
Y2H Array
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Dermatitis, Atopic

Atopic Dermatitis

Atopic Eczema

Dermatitis, Atopic, Susceptibility To, 1

Atod

Eczema, Atopic

Dermatitis, Atopic 1

Allergic Dermatitis

Atopic Neurodermatitis

Besnier'S Prurigo

Dermatitis, Atopic, 1

Dermatitis Atopic

Eczema

Besnier Prurigo

Peroxisome Biogenesis Disorder 11a

PBD11A

Peroxisome Biogenesis Disorder Complementation Group 13

PBD-CG13

Cg13

Pbd-Cgh

Peroxisome Biogenesis Disorder Complementation Group H

Peroxisome Biogenesis Disorder, Type 11a

Peroxisome Biogenesis Disorder, Complementation Group 13

Diffuse Large B-Cell Lymphoma

Dlbcl

Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

Large B-Cell Diffuse Lymphoma

Lymphoma, Large B-Cell, Diffuse

Dlbcl - [Diffuse Large B-Cell Lymphoma]

Diffuse Large Beta Cell Lymphoma

T-Cell Acute Lymphoblastic Leukemia

T-Cell Leukemia

Acute T Cell Leukemia

Precursor T Lymphoblastic Leukemia

Precursor T-Lymphoblastic Lymphoma/Leukemia

T Acute Lymphoblastic Leukemia

T-Cell Acute Lymphocytic Leukaemia

T-Cell Lymphoblastic Leukemia/Lymphoma

Leukemia T-Cell

Leukemia, T-Cell

Leukemia, Acute, Lymphoblastic, T-Cell

Leukemia, T-Cell Acute Lymphoblastic

Leukemia, Acute T-Cell

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Precursor T-Cell Lymphoblastic Lymphoma

Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma

Immunodeficiency 92

IMD92

Arthritis

Inflammatory Joint Disease

Inflammatory Disorder Of Joint

Lymphoma, Hodgkin, Classic

Hodgkin Lymphoma

Hodgkin Disease

Hodgkin'S Lymphoma

Hodgkins Lymphoma

Classic Hodgkin Lymphoma

CHL

Hodgkin Lymphoma, Susceptibility To

Hl

Hodgkin'S Sarcoma

Stage I Subdiaphragmatic Hodgkin Lymphoma

Stage Ii Subdiaphragmatic Hodgkin Lymphoma

Lymphoma, Hodgkin'S

Classic Hodgkin Disease

Hodgkin'S Disease

Lymphoma, Hodgkin, Susceptibility To

Hodgkin'S Disease Of Intrapelvic Lymph Nodes

Hodgkin'S Disease Of Lymph Nodes Of Inguinal Region And/Or Lower Limb

Malignant Lymphogranuloma

Malignant Lymphogranulomatosis

Malignant Hodgkin Lymphoma

Classical Hodgkin Lymphoma, Type Not Specified

Colitis
Ethmoid Sinus Adenocarcinoma

Adenocarcinoma Of Ethmoid Sinus

Adenocarcinoma Of The Ethmoid Sinus

Lymphoma

Lymphoid Cancer

Lymphomas

Lymphoid Cancers

Lymphoid Neoplasm

Lymphoma Nos

Nhl - [Non-Hodgkin Lymphoma]

Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma, Nos

Non-Hodgkin Malignant Lymphoma Nos

Immune Deficiency Disease

Immunodeficiency

Primary Immunodeficiency Disease

Primary Immunodeficiency

Immunologic Deficiency Syndromes

Hypoimmunity

Immune Deficiency Disorder

Immunodeficiency Syndrome

Immune Disorder

Primary Immune Deficiency Disorder

Immune System Diseases

Human Immunodeficiency Virus Infection

Hiv - [Human Immunodeficiency Virus Infection]

Hiv Positive Nos

Hiv Disease

Acquired Immune Deficiency Syndrome-Related Complex

Aids-Like Syndrome

Aids-Related Complex Nos

Arc - [Aids-Related Complex]

Immunodeficiency Due To Human Immunodeficiency Virus Infection

Unspecified Human Immunodeficiency Virus Disease

Hiv Disease Nos

Human Immunodeficiency Virus Positive Nos

Hiv Nos

Deficiency Of Complement Initial Pathway

Deficiency Of Complement Terminal Pathway

Cfdd - [Complement Factor D Deficiency]

Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency

Nonfamilial Hypogammaglobulinaemia

Common Variable Immune Deficiency

Nonfamilial Agammaglobulinaemia

Common Variable Agammaglobulinaemia

Agammaglobulinaemia Nos

Agammaglobulinaemia Antibody Deficiency Syndrome

Hypogammaglobulinaemia Antibody Deficiency Syndrome

Acquired Agammaglobulinaemia Nos

Hypogammaglobulinaemia Nos

Hyper Igm

Leukemia, Chronic Lymphocytic

Chronic Lymphocytic Leukemia

B-Cell Chronic Lymphocytic Leukemia

CLL

B-Cell Chronic Lymphoid Leukemia

Chronic Lymphatic Leukemia

Chronic Lymphocytic Leukaemia

Lymphoplasmacytic Leukemia

Small Lymphocytic Lymphoma

Leukemia, Chronic Lymphatic

B-Cell Chronic Lymphocytic Leukaemia

Chronic Lymphatic Leukaemia

Lymphoplasmacytic Leukaemia

B Cell Chronic Lymphocytic Leukemia

Chronic B-Cell Lymphocytic Leukemia

Leukemia, Lymphocytic, Chronic

B-Cll

Chronic Lymphoid Leukemia

Leukemia Lymphocytic Chronic

Lymphoma Small Lymphocytic

Leukemia, Lymphocytic, Chronic, B-Cell

Nervous System Disease

Abnormality Of The Nervous System

Nervous System Diseases

Nervous System Disorder

Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic

Ulcerative Colitis

Colitis Gravis

Left Sided Ulcerative Colitis

Left-Sided Ulcerative Colitis

Idiopathic Proctocolitis

Inflammatory Bowel Disease, Ulcerative Colitis Type

Uc

Colitis Ulcerative

Colitis, Ulcerative

Chronic Left-Sided Ulcerative Colitis

Uc - [Ulcerative Colitis]

Chronic Ulcerative Enteritis

Mucosal Proctocolitis

Ulcerative Mucosal Proctocolitis

Left Hemicolitis

Alzheimer Disease 7

Ad7

Alzheimer'S Disease 7

Alzheimer Disease, Familial, 7

Alzheimer Disease-7

Alzheimer Disease, Familial 7

Follicular Lymphoma

Lymphoma, Follicular

Lymphoma Follicular

Brill-Symmers' Disease

Large Cell Follicular Non-Hodgkin Lymphoma

Diffuse Follicle Centre Lymphoma

Diffuse Follicular Lymphoma Nos

Follicular Nodular Non-Hodgkin Lymphoma, Unspecified

Follicular Large Cell Cleaved Or Noncleaved Lymphoma

Large Cell Follicular Noncleaved Lymphoma

Follicular Lymphoma With Or Without Diffuse Areas

Histiocytic Follicular Lymphoma

Histiocytic Nodular Lymphoma

Histiocytic Nodular Malignant Lymphoma

Large Cell Follicular Lymphoma

Large Cell Noncleaved Follicular Lymphoma

Large Cell Noncleaved Follicular Malignant Lymphoma

Nodular Reticulum Cell Sarcoma

Noncleaved Follicular Lymphoma

Hypersplenism

Hypersplenia

Big Spleen Syndrome

Hyperfunction Of Spleen

Increased Splenic Activity

Spleen Metaplasia

Splenic Metaplasia

Primary Mediastinal B-Cell Lymphoma

Large Cell Lymphoma Of The Mediastinum

Mediastinal Diffuse Large-Cell Lymphoma With Sclerosis

Primary Mediastinal Clear Cell Lymphoma Of B-Cell Type

Internal Hordeolum
Endometrial Cancer

Endometrial Carcinoma

Endometrial Neoplasm

Malignant Neoplasm Of Endometrium

Endometrioid Carcinoma

Endometrial Neoplasms

Carcinoma, Endometrioid

Endometrial Cancer, Familial

Endometrial Carcinoma, Somatic

Endometrial Cancer, Susceptibility To

Endometrial Ca

Malignant Endometrial Neoplasm

Neoplasm Of Endometrium

Primary Malignant Neoplasm Of Endometrium

Tumor Of Endometrium

Carcinoma Of The Endometrium

Endometrioid Carcinoma Of Female Reproductive System

ENDMC

Carcinoma Endometrioid

Endometrial Cancers

Cancer, Endometrial

Uterine Corpus Cancer

Reticuloendotheliosis, X-Linked

Reticuloendotheliosis

Rheumatoid Arthritis

RA

Arthritis, Rheumatoid

Rheumatoid Arthritis, Susceptibility To

Arthritis Or Polyarthritis, Rheumatic

Atrophic Arthritis

Rheumatism Arthritis

Rheumatoid Polyarthritis

Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon

Renal Pelvis Transitional Cell Carcinoma

Urothelial Cell Carcinoma Of Renal Pelvis

Renal Pelvis Urothelial Carcinoma

Transitional Cell Carcinoma Of Renal Pelvis

Pancreatic Cancer

Pancreatic Carcinoma

Familial Pancreatic Carcinoma

Pancreatic Neoplasm

Carcinoma Of Pancreas

Pancreatic Carcinoma, Familial

Malignant Neoplasm Of Pancreas

Pancreatic Acinar Carcinoma

Pancreatic Tumor

Familial Pancreatic Cancer

Neoplasm Of The Pancreas

Pancreatic Carcinoma, Somatic

Pancreatic Cancer, Somatic

Ca Body Of Pancreas

Ca Head Of Pancreas

Ca Tail Of Pancreas

Malignant Neoplasm Of Body Of Pancreas

Malignant Neoplasm Of Head Of Pancreas

Malignant Neoplasm Of Tail Of Pancreas

Pancreas Neoplasm

Exocrine Cancer

Exocrine Pancreas Carcinoma

Hereditary Pancreatic Cancer

Hereditary Pancreatic Carcinoma

PNCA

Cancer Of The Pancreas

Pancreatic Cancer, Susceptibility To

Carcinoma Of Head Of Pancreas

Pancreatic Neoplasms

Pancreatic Tumors

Cancer, Pancreatic

Cancer Of Pancreas

Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site

B-Cell Lymphoma

Lymphoma, B-Cell

B-Cell Lymphomas

B-Cell Lymphocytic Neoplasm

Lymphoma B-Cell

B-Cell Lymphoma Nos

Combined Immunodeficiency

Combined T Cell And B Cell Immunodeficiency

Congenital Combined Immunodeficiency

Syndrome With Combined Immunodeficiency

Combined T And B Cell Immunodeficiency

Combined Immunity Deficiency

Combined Immunodeficiency Syndrome

Combined T-Cell And B-Cell Immunodeficiency

Lymphopenic Agammaglobulinaemia

Inhibited Male Orgasm

Male Orgasmic Disorder

Psychosexual Dysfunction With Male Orgasmic Disorder

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta REL VGNC VGNC:76892
Mus musculus REL MGD MGI:97897
Felis catus REL VGNC VGNC:69282
Canis familiaris REL VGNC VGNC:45465
Bos taurus REL VGNC VGNC:33857
Rattus norvegicus REL RGD RGD:1311231
Macaca fascicularis REL NCBI NCBI:102116653
Canis lupus familiaris REL NCBI
Others REL NCBI