NXT2 - nuclear transport factor 2 like export factor 2 Gene

中文名称：核运输因子 2 就样出口因子 2

种属: Homo sapiens

同用名: P15-2

基因 ID: 55916 | 基因类型: protein coding

关于 NXT2

Cytogenetic location: Xq23 Genomic coordinates (GRCh38): X:109,535,824-109,544,698 (from NCBI)

This gene has 4 transcripts (splice variants), 218 orthologues and 2 paralogues. Broad expression in testis (RPKM 16.8), bone marrow (RPKM 5.3) and 23 other tissues.

功能概要

该基因编码的蛋白质包含一个核转运因子 2 (NTF2) 结构域，它在细胞质和细胞核之间的大分子、离子和小分子的运输中起着重要作用。这种蛋白质也可能在 mRNA 核输出中起作用。已经注意到该基因编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2011 年 6 月]

The protein encoded by this gene contains a nuclear transport factor 2 (NTF2) domain, which plays an important role in the trafficking of macromolecules, ions, and small molecules between the cytoplasm and nucleus. This protein may also have a role in mRNA nuclear export. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jun 2011]

NXT2 基因产物(3)

mRNA	Protein	Name
NM_001242617.2	NP_001229546.1	NTF2-related export protein 2 isoform 2
NM_001242618.2	NP_001229547.1	NTF2-related export protein 2 isoform 3
NM_018698.5	NP_061168.2	NTF2-related export protein 2 isoform 1

基因本体论

分子功能
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	16189514	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
part of nuclear RNA export factor complex	IPI IPI: 通过物理相互作用推断	25416956	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

NXT2 蛋白结构

NTF2

0
100
142 a.a.

蛋白主名

其他名称

NTF2-related export protein 2

protein p15-2

NXT2 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	NXT2	Q9NPJ8	CCDC102B	Homo sapiens	Q68D86	Y2H Prey Pooling	25416956
Intra	NXT2	Q9NPJ8	HEL-S-30	Homo sapiens	V9HWB8	Y2H Array	25416956
Intra	NXT2	Q9NPJ8	PTPN3	Homo sapiens	P26045	Y2H Prey Pooling	25416956
Intra	NXT2	Q9NPJ8	SSBP3	Homo sapiens	Q9BWW4	Validated Y2H	25416956
Intra	NXT2	Q9NPJ8	REL	Homo sapiens	Q04864	Validated Y2H	25416956
Intra	NXT2	Q9NPJ8	GOLGA2	Homo sapiens	Q08379	Y2H Array	25416956
Intra	NXT2	Q9NPJ8	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	25416956
Intra	NXT2	Q9NPJ8	GOLGA2	Homo sapiens	Q08379	Validated Y2H	25416956
Intra	NXT2	Q9NPJ8	LNX1	Homo sapiens	Q8TBB1	Validated Y2H	25416956
Intra	NXT2	Q9NPJ8	LNX1	Homo sapiens	Q8TBB1	Y2H Prey Pooling	25416956
Intra	NXT2	Q9NPJ8	TRIM23	Homo sapiens	P36406	Validated Y2H	25416956
Intra	NXT2	Q9NPJ8	TRIM23	Homo sapiens	P36406	Y2H Array	25416956
Intra	NXT2	Q9NPJ8	CEP63	Homo sapiens	Q96MT8	Y2H Prey Pooling	25416956
Intra	NXT2	Q9NPJ8	CEP63	Homo sapiens	Q96MT8	Validated Y2H	25416956
Intra	NXT2	Q9NPJ8	NXF3	Homo sapiens	Q9H4D5	Y2H Array	25416956
Intra	NXT2	Q9NPJ8	NXF3	Homo sapiens	Q9H4D5	Y2H Pooling	16189514
Intra	NXT2	Q9NPJ8	NXF3	Homo sapiens	Q9H4D5	Y2H Array	31515488
Intra	NXT2	Q9NPJ8	NXF3	Homo sapiens	Q9H4D5	Validated Y2H	25416956
Intra	NXT2	Q9NPJ8	USP54	Homo sapiens	Q70EL1	Y2H Array	25416956
Intra	NXT2	Q9NPJ8	USP54	Homo sapiens	Q70EL1	Y2H Prey Pooling	25416956
Intra	NXT2	Q9NPJ8	USP54	Homo sapiens	Q70EL1	Validated Y2H	25416956

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Cancerophobia

Cancer Phobia

Fear Of Getting Cancer

Nosophobia

Amme Complex

Alport Syndrome, Mental Retardation, Midface Hypoplasia, And Elliptocytosis	ATS-MR
Alport Syndrome-Intellectual Disability-Midface Hypoplasia-Elliptocytosis Syndrome	Chromosome Xq22.3 Telomeric Deletion Syndrome
Amme Syndrome	Alport Syndrome With Intellectual Disability, Midface Hypoplasia And Elliptocytosis

Trachea Adenoid Cystic Carcinoma

Tracheal Adenoid Cystic Carcinoma

Adenoid Cystic Carcinoma Of Trachea

Congenital Myasthenic Syndrome 7

Cms7	Congenital Myasthenic Syndrome 7 Presynaptic
Myasthenic Syndrome, Congenital, Type 7, Presynaptic

Non-Syndromic X-Linked Intellectual Disability

X-Linked Non-Syndromic Intellectual Disability	Non-Specific X-Linked Mental Retardation
X-Linked Non-Specific Intellectual Disability

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS09721	NXT2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Macaca mulatta	NXT2	VGNC	VGNC:75430
Mus musculus	NXT2	MGD	MGI:2147914
Rattus norvegicus	NXT2	RGD	RGD:1560204
Bos taurus	NXT2	VGNC	VGNC:32385
Canis familiaris	NXT2	VGNC	VGNC:44080

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

NXT2 - nuclear transport factor 2 like export factor 2 Gene

关于 NXT2

功能概要

NXT2 基因产物(3)

NXT2 蛋白结构

NXT2 蛋白互作信息

关联疾病

直系同源

热门区域

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NXT2 - nuclear transport factor 2 like export factor 2 Gene

关于 NXT2

功能概要

NXT2 基因产物(3)

NXT2 蛋白结构

NXT2 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z