2. Gene
  3. SSBP3 - single stranded DNA binding protein 3 Gene

SSBP3 - single stranded DNA binding protein 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：单链 DNA 结合蛋白 3

种属: Homo sapiens

同用名: CSDP; SSDP; SSDP1

基因 ID: 23648 | 基因类型: protein coding

关于 SSBP3

Cytogenetic location: 1p32.3 Genomic coordinates (GRCh38): 1:54,225,432-54,413,490 (from NCBI)

This gene has 16 transcripts (splice variants), 221 orthologues and 2 paralogues. Ubiquitous expression in ovary (RPKM 35.7), brain (RPKM 22.6) and 24 other tissues.

功能概要

预测可实现单链 DNA 结合活性和转录共激活因子活性。预计参与头部发育和 RNA 聚合酶 II 对转录的正调控。预测作用于造血祖细胞分化的上游或内部。预计是含蛋白质复合物的一部分。预计活跃于核心。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable single-stranded DNA binding activity and transcription coactivator activity. Predicted to be involved in head development and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

SSBP3 基因产物(11)

mRNA Protein Name
NM_001009955.4 NP_001009955.1 single-stranded DNA-binding protein 3 isoform c
NM_001394360.1 NP_001381289.1 single-stranded DNA-binding protein 3 isoform d
NM_001394361.1 NP_001381290.1 single-stranded DNA-binding protein 3 isoofrm e
NM_001394362.1 NP_001381291.1 single-stranded DNA-binding protein 3 isosform f
NM_001394363.1 NP_001381292.1 single-stranded DNA-binding protein 3 isoform g
NM_001394364.1 NP_001381293.1 single-stranded DNA-binding protein 3 isoform h
NM_001394365.1 NP_001381294.1 single-stranded DNA-binding protein 3 isoform i
NM_001394366.1 NP_001381295.1 single-stranded DNA-binding protein 3 isoform i
NM_001394367.1 NP_001381296.1 single-stranded DNA-binding protein 3 isoform j
NM_018070.5 NP_060540.2 single-stranded DNA-binding protein 3 isoform b
NM_145716.4 NP_663768.1 single-stranded DNA-binding protein 3 isoform a
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18330356 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SSBP3 蛋白结构

SSDP

SSDP: Single-stranded DNA binding protein, SSDP (81 - 370)

  • 0
  • 100
  • 200
  • 300
  • 388 a.a.
蛋白主名 其他名称

single-stranded DNA-binding protein 3

sequence-specific single-stranded-DNA-binding protein

SSBP3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SSBP3 Q9BWW4 TBC1D23 Homo sapiens Q9NUY8-2
Y2H Prey Pooling
25416956
种属内
SSBP3 Q9BWW4 TBC1D23 Homo sapiens Q9NUY8-2
Validated Y2H
25416956
种属内
SSBP3 Q9BWW4 NXT2 Homo sapiens Q9NPJ8-3
Validated Y2H
32296183
种属内
SSBP3 Q9BWW4 TBC1D23 Homo sapiens Q9NUY8
Y2H Array
25416956
种属内
SSBP3 Q9BWW4 LMX1B Homo sapiens O60663
Anti Tag CoIP
33961781
种属内
SSBP3 Q9BWW4 LMX1B Homo sapiens O60663
Pull Down
30833792
种属内
SSBP3 Q9BWW4 IL36RN Homo sapiens Q9UBH0
Validated Y2H
32296183
种属内
SSBP3 Q9BWW4 YES1 Homo sapiens P07947
Y2H Array
25416956
种属内
SSBP3 Q9BWW4 LDB1 Homo sapiens Q86U70
Y2H Array
25416956
种属内
SSBP3 Q9BWW4 LDB1 Homo sapiens Q86U70
Anti Tag CoIP
33961781
种属内
SSBP3 Q9BWW4 LDB1 Homo sapiens Q86U70
Pull Down
30833792
种属内
SSBP3 Q9BWW4 LDB1 Homo sapiens Q86U70
Y2H Prey Pooling
25416956
种属内
SSBP3 Q9BWW4 LDB1 Homo sapiens Q86U70
Validated Y2H
25416956
种属内
SSBP3 Q9BWW4 EWSR1 Homo sapiens Q01844
Y2H Prey Pooling
25416956
种属内
SSBP3 Q9BWW4 NXT2 Homo sapiens Q9NPJ8
Y2H Prey Pooling
25416956
种属内
SSBP3 Q9BWW4 NXT2 Homo sapiens Q9NPJ8
Y2H Array
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Panhypopituitarism, X-Linked

PHPX

X-Linked Panhypopituitarism

Pituitary Dwarfism Iv

Panhypopituitarism X-Linked

Pituitary Dwarfism Iv, Formerly

Panhypopituitarism - X-Linked
Cockayne Syndrome

Cockayne'S Syndrome

Dwarfism-Retinal Atrophy-Deafness Syndrome

Neill-Dingwall Syndrome

Progeria-Like Syndrome

Progeroid Nanism

Cs
Lissencephaly

Pachygyria

Broad Gyri Of Cerebrum

Large Gyri Of Cerebrum

Macrogyria
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13807 SSBP3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SSBP3 RGD RGD:621502
Bos taurus SSBP3 VGNC VGNC:35308
Mus musculus SSBP3 MGD MGI:1919725
Canis familiaris SSBP3 VGNC VGNC:53451
Felis catus SSBP3 VGNC VGNC:107642
Macaca mulatta SSBP3 VGNC VGNC:77926
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