NUDT14 - nudix hydrolase 14 Gene

中文名称：nudix 水解酶 14

种属: Homo sapiens

同用名: UGPP; UGPPase

关于 NUDT14

功能概要

该基因编码的蛋白质是 Nudix 水解酶家族的成员。 Nudix 水解酶从细胞中消除潜在毒性的核苷酸代谢物，并调节许多不同核苷酸底物、辅助因子和信号分子的浓度和可用性。该酶包含 Nudix 水解酶结构域，是一种 UDPG 焦磷酸酶，可水解 UDPG 以产生葡萄糖 1-磷酸和 UMP。已发现该基因编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2016 年 1 月]

The protein encoded by this gene is a member of the Nudix hydrolase family. Nudix hydrolases eliminate potentially toxic nucleotide metabolites from the cell and regulate the concentrations and availability of many different nucleotide substrates, cofactors, and signaling molecules. This Enzyme contains a Nudix hydrolase domain and is a UDPG pyrophosphatase that hydrolyzes UDPG to produce glucose 1-phosphate and UMP. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]