2. Apoptosis NF-κB Immunology/Inflammation
  3. TNF Receptor NF-κB NO Synthase
  4. rel-Cleroindicin F

rel-Cleroindicin F  (Synonyms: Rengyolone)

目录号: HY-N3602A
产品使用指南 技术支持

rel-Cleroindicin F (Rengyolone) 是一种可以从连翘果实中分离出来的环己基乙酰类化合物，具有抗炎活性。rel-Cleroindicin F 对一氧化氮 (NO) 和肿瘤坏死因子-α (TNF-α) 的生成有强烈的抑制作用。rel-Cleroindicin F 通过下调 LPS (HY-D1056) 刺激的 RAW 264.7 细胞中的 NF-κB 和 NF-κB 激酶活性，抑制诱导型一氧化氮合酶 (NO Synthase) 表达和一氧化氮生成。

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rel-Cleroindicin F Chemical Structure

rel-Cleroindicin F Chemical Structure

CAS No. : 94535-01-0

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Other Forms of rel-Cleroindicin F:

rel-Cleroindicin F 相关抗体

Top Publications Citing Use of Products

查看 TNF Receptor 亚型特异性产品:

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TNFRSF1A/CD120a TNFRSF5/CD40 TNFRSF6/Fas/CD95 TNFRSF7/CD27 TNFRSF8/CD30 TNFRSF9/4-1BB/CD137 TNFRSF16/NGF Receptor/CD271 TNFRSF18/GITR/CD357

查看 NF-κB 亚型特异性产品:

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NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

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nNOS iNOS eNOS

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

rel-Cleroindicin F (Rengyolone) is a cyclohexyl acetyl compound that can be isolated from the fruit of forsythia and has anti-inflammatory activity. It strongly inhibits the production of nitric oxide (NO) and tumor necrosis factor-alpha (TNF-α). rel-Cleroindicin F does this by downregulating the activity of NF-κB and NF-κB kinases in RAW 264.7 cells stimulated by LPS (HY-D1056), thus inhibiting the expression of inducible nitric oxide synthase (NO Synthase) and nitric oxide production[1].

分子量

154.16

Formula

C8H10O3
CAS 号
中文名称

哈里瑞酮
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

rel-Cleroindicin F 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

rel-Cleroindicin F94535-01-0Rengyolone哈里瑞酮TNF ReceptorNF-κBNO SynthaseTumor Necrosis Factor ReceptorTNFRNuclear factor-κBNuclear factor-kappaBNitric oxide synthasesNOSRAW 264.7nitric oxide productionTNF-αInhibitorinhibitorinhibit

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