2. Gene
  3. SLC41A3 - solute carrier family 41 member 3 Gene

SLC41A3 - solute carrier family 41 member 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 41 成员 3

种属: Homo sapiens

同用名: SLC41A1-L2

基因 ID: 54946 | 基因类型: protein coding

关于 SLC41A3

Cytogenetic location: 3q21.2-q21.3 Genomic coordinates (GRCh38): 3:126,006,357-126,101,520 (from NCBI)

This gene has 22 transcripts (splice variants), 268 orthologues and 2 paralogues. Ubiquitous expression in testis (RPKM 23.3), ovary (RPKM 19.3) and 25 other tissues.

功能概要

预测可启用阳离子跨膜转运蛋白活性。预计参与阳离子跨膜转运。位于质膜。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable cation transmembrane transporter activity. Predicted to be involved in cation transmembrane transport. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC41A3 基因产物(5)

mRNA Protein Name
NM_001008485.2 NP_001008485.2 solute carrier family 41 member 3 isoform 1
NM_001008486.2 NP_001008486.2 solute carrier family 41 member 3 isoform 3
NM_001008487.2 NP_001008487.1 solute carrier family 41 member 3 isoform 4
NM_001164475.2 NP_001157947.1 solute carrier family 41 member 3 isoform 5
NM_017836.4 NP_060306.4 solute carrier family 41 member 3 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables magnesium:sodium antiporter activity IDA
IDA: 通过直接分析推断
27302215 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in mitochondrial magnesium ion transmembrane transport IDA
IDA: 通过直接分析推断
27302215 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
27302215 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SLC41A3 蛋白结构

MgtE

MgtE: Divalent cation transporter (106 - 240)

MgtE

MgtE: Divalent cation transporter (318 - 456)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 507 a.a.
蛋白主名 其他名称

solute carrier family 41 member 3

SLC41A1-like 2

SLC41A3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SLC41A3 Q96GZ6 BDNF Homo sapiens P23560-2
Y2H Array
32814053
Intra SLC41A3 Q96GZ6 BDNF Homo sapiens P23560-2
Validated Y2H
32814053
Intra SLC41A3 Q96GZ6 BDNF Homo sapiens P23560-2
Y2H Pooling
32814053
Intra SLC41A3 Q96GZ6 REL Homo sapiens Q04864
Y2H Prey Pooling
25416956
Intra SLC41A3 Q96GZ6 SUFU Homo sapiens Q9UMX1
Y2H Prey Pooling
32296183
Intra SLC41A3 Q96GZ6 SUFU Homo sapiens Q9UMX1
Validated Y2H
32296183
Intra SLC41A3 Q96GZ6 SUFU Homo sapiens Q9UMX1
Y2H Array
32296183
Intra SLC41A3 Q96GZ6 SMCO4 Homo sapiens Q9NRQ5
Validated Y2H
32296183
Intra SLC41A3 Q96GZ6 NHERF4 Homo sapiens Q86UT5
Validated Y2H
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Hypomagnesemia 1, Intestinal

Intestinal Hypomagnesemia 1

HOMG1

Hypomagnesemia With Secondary Hypocalcemia

Hsh

Hypomagnesemic Tetany

Intestinal Hypomagnesemia With Secondary Hypocalcemia

Homg

Hypomagnesemia Caused By Selective Magnesium Malabsorption

Hypomagnesemia Intestinal Type 1

Primary Hypomagnesemia With Secondary Hypocalcemia

Phsh

Hypomagnesemia, Intestinal, With Secondary Hypocalcemia

Familial Primary Hypomagnesemia With Hypocalcuria

Hypomagnesemia 1

Hypomagnesmic Tetany
Primary Hypomagnesemia

Familial Primary Hypomagnesemia

Homg

Primary Familial Hypomagnesemia

Genetic Primary Hypomagnesemia

Hypomagnesemia 1, Intestinal
Nephronophthisis

Medullary Cystic Disease

Medullary Cystic Kidney

Nph

Nphp

Kidney Disease, Cystic, Medullary
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13247 SLC41A3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris SLC41A3 VGNC VGNC:46414
Bos taurus SLC41A3 VGNC VGNC:58412
Rattus norvegicus SLC41A3 RGD RGD:1589573
Mus musculus SLC41A3 MGD MGI:1918949
Macaca mulatta SLC41A3 VGNC VGNC:77586
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