2. Gene
  3. EML2 - EMAP like 2 Gene

EML2 - EMAP like 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：EMAP 样 2

种属: Homo sapiens

同用名: ELP70; EMAP2; EMAP-2

基因 ID: 24139 | 基因类型: protein coding

关于 EML2

Cytogenetic location: 19q13.32 Genomic coordinates (GRCh38): 19:45,609,400-45,645,629 (from NCBI)

This gene has 31 transcripts (splice variants), 187 orthologues and 9 paralogues. Ubiquitous expression in esophagus (RPKM 8.7), skin (RPKM 8.5) and 25 other tissues.

功能概要

启用微管结合活动。参与微管聚合的负调控和微管成核的调控。与有丝分裂纺锤体共定位。 [由基因组资源联盟提供，2022 年 4 月]

Enables microtubule binding activity. Involved in negative regulation of microtubule polymerization and regulation of microtubule nucleation. Colocalizes with mitotic spindle. [provided by Alliance of Genome Resources, Apr 2022]

EML2 基因产物(7)

mRNA Protein Name
NM_001193268.3 NP_001180197.1 echinoderm microtubule-associated protein-like 2 isoform 1
NM_001193269.2 NP_001180198.1 echinoderm microtubule-associated protein-like 2 isoform 3
NM_001352051.2 NP_001338980.1 echinoderm microtubule-associated protein-like 2 isoform 4
NM_001352052.1 NP_001338981.1 echinoderm microtubule-associated protein-like 2 isoform 5
NM_001352053.2 NP_001338982.1 echinoderm microtubule-associated protein-like 2 isoform 6
NM_001352054.2 NP_001338983.1 echinoderm microtubule-associated protein-like 2 isoform 7
NM_012155.4 NP_036287.1 echinoderm microtubule-associated protein-like 2 isoform 2

EML2 蛋白结构

HELP

HELP: HELP motif (17 - 94)

WD40

WD40: WD domain, G-beta repeat (99 - 123)

WD40

WD40: WD domain, G-beta repeat (288 - 321)

WD40

WD40: WD domain, G-beta repeat (374 - 405)

WD40

WD40: WD domain, G-beta repeat (454 - 487)

WD40

WD40: WD domain, G-beta repeat (500 - 534)

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  • 649 a.a.
蛋白主名 其他名称

echinoderm microtubule-associated protein-like 2

echinoderm MT-associated protein (EMAP)-like protein 70

EML2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
EML2 O95834 EXD1 Homo sapiens Q8NHP7
Y2H Prey Pooling
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Sulfonamide Allergy
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04354 EML2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus EML2 VGNC VGNC:28476
Felis catus EML2 VGNC VGNC:61849
Mus musculus EML2 MGD MGI:1919455
Rattus norvegicus EML2 RGD RGD:621066
Canis familiaris EML2 VGNC VGNC:40347
Others EML2 NCBI
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