1. Gene
  2. ALOX5 - arachidonate 5-lipoxygenase Gene

ALOX5 - arachidonate 5-lipoxygenase Gene

中文名称:花生四烯酸 5-脂氧合酶

种属: Homo sapiens

同用名: 5-LO; 5LPG; LOG5; 5-LOX

基因 ID: 240 | 基因类型: protein coding

关于 ALOX5

Cytogenetic location: 10q11.21 Genomic coordinates (GRCh38): 10:45,374,216-45,446,117 (from NCBI)

This gene has 7 transcripts (splice variants), 1 gene allele, 221 orthologues, 5 paralogues and is associated with 1 phenotype. Broad expression in bone marrow (RPKM 35.1), lung (RPKM 26.8) and 15 other tissues.

功能概要

该基因编码脂肪氧化酶基因家族的一个成员,并在花生四烯酸合成白三烯中发挥双重作用。编码的蛋白质在骨髓来源的细胞中特异性表达,催化花生四烯酸转化为 5 (S) -hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid,并进一步转化为烯丙基环氧化物 5 (S) -trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4) 。白三烯是许多炎症和过敏性疾病的重要介质。该基因启动子区域的突变导致对用于治疗哮喘的抗白三烯药物的反应减弱,并且还可能与动脉粥样硬化和几种癌症有关。已发现该基因编码不同亚型的可变剪接转录物变体。[RefSeq 提供,2012 年 1 月]

This gene encodes a member of the Lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

ALOX5 基因产物(13)

mRNA Protein Name
NM_000698.5 NP_000689.1 polyunsaturated fatty acid 5-lipoxygenase isoform 1
XM_047424934.1 XP_047280890.1 polyunsaturated fatty acid 5-lipoxygenase isoform X1
NM_001256154.3 NP_001243083.1 polyunsaturated fatty acid 5-lipoxygenase isoform 3
XM_047424936.1 XP_047280892.1 polyunsaturated fatty acid 5-lipoxygenase isoform X2
NM_001320861.2 NP_001307790.1 polyunsaturated fatty acid 5-lipoxygenase isoform 4
NM_001320862.2 NP_001307791.1 polyunsaturated fatty acid 5-lipoxygenase isoform 5
XM_047424937.1 XP_047280893.1 polyunsaturated fatty acid 5-lipoxygenase isoform X3
NM_001256153.3 NP_001243082.1 polyunsaturated fatty acid 5-lipoxygenase isoform 2
NM_000698.5 NP_000689.1 polyunsaturated fatty acid 5-lipoxygenase isoform 1
NM_001256153.3 NP_001243082.1 polyunsaturated fatty acid 5-lipoxygenase isoform 2
NM_001256154.3 NP_001243083.1 polyunsaturated fatty acid 5-lipoxygenase isoform 3
NM_001320861.2 NP_001307790.1 polyunsaturated fatty acid 5-lipoxygenase isoform 4
NM_001320862.2 NP_001307791.1 polyunsaturated fatty acid 5-lipoxygenase isoform 5
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables arachidonate 5-lipoxygenase activity IDA
IDA: 通过直接分析推断
8615788 GOA
enables iron ion binding IDA
IDA: 通过直接分析推断
21233389 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
7929073 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in leukocyte chemotaxis involved in inflammatory response IMP
IMP: 通过突变表型推断
17114001 GOA
involved in leukotriene A4 biosynthetic process IDA
IDA: 通过直接分析推断
24282679 GOA
involved in leukotriene A4 biosynthetic process IMP
IMP: 通过突变表型推断
31664810 GOA
involved in leukotriene biosynthetic process IDA
IDA: 通过直接分析推断
21233389 GOA
involved in lipoxin biosynthetic process IMP
IMP: 通过突变表型推断
31664810 GOA
involved in negative regulation of inflammatory response IDA
IDA: 通过直接分析推断
21206090 GOA
involved in regulation of inflammatory response IMP
IMP: 通过突变表型推断
17114001 GOA
involved in regulation of reactive oxygen species biosynthetic process IMP
IMP: 通过突变表型推断
26210919 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
19233132 GOA
located in nuclear envelope IDA
IDA: 通过直接分析推断
19233132 GOA
located in nuclear envelope lumen IDA
IDA: 通过直接分析推断
8245774 GOA
located in nuclear matrix IDA
IDA: 通过直接分析推断
19233132 GOA
located in nuclear membrane IDA
IDA: 通过直接分析推断
8245774 GOA
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
19022417 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

ALOX5 蛋白结构

PLAT

PLAT: PLAT/LH2 domain (4 - 112)

Lipoxygenase

Lipoxygenase: Lipoxygenase (152 - 665)

  • 0
  • 200
  • 400
  • 600
  • 674 a.a.
蛋白主名 其他名称

polyunsaturated fatty acid 5-lipoxygenase

LOX-5

arachidonic acid 5-lipoxygenase

leukotriene A4 synthase

ALOX5 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra ALOX5 P09917 NUTM1 Homo sapiens Q86Y26
Y2H Prey Pooling
25416956
Intra ALOX5 P09917 CEP57L1 Homo sapiens Q8IYX8-2
Validated Y2H
25416956
Intra ALOX5 P09917 HHIPL2 Homo sapiens Q6UWX4
Y2H Array
25910212
Intra ALOX5 P09917 HHIPL2 Homo sapiens Q6UWX4
Y2H Array
25416956
Intra ALOX5 P09917 HHIPL2 Homo sapiens Q6UWX4
Validated Y2H
25910212
Intra ALOX5 P09917 HHIPL2 Homo sapiens Q6UWX4
Y2H Bait-Prey Pool
25910212
Intra ALOX5 P09917 LCN1 Homo sapiens P31025
Y2H Prey Pooling
32296183
Intra ALOX5 P09917 LCN1 Homo sapiens P31025
Validated Y2H
32296183
Intra ALOX5 P09917 LCN1 Homo sapiens P31025
Y2H Array
32296183
Intra ALOX5 P09917 CEP63 Homo sapiens Q96MT8-3
Y2H Array
25910212
Intra ALOX5 P09917 CEP63 Homo sapiens Q96MT8-3
Y2H Prey Pooling
32296183
Intra ALOX5 P09917 CEP63 Homo sapiens Q96MT8-3
Validated Y2H
32296183
Intra ALOX5 P09917 CEP63 Homo sapiens Q96MT8-3
Y2H Array
32296183
Intra ALOX5 P09917 CEP63 Homo sapiens Q96MT8-3
Y2H Bait-Prey Pool
25910212
Intra ALOX5 P09917 CEP63 Homo sapiens Q96MT8-3
Validated Y2H
25910212
Intra ALOX5 P09917 CEP57L1 Homo sapiens Q6P2R3
Y2H Array
25910212
Intra ALOX5 P09917 CEP57L1 Homo sapiens Q6P2R3
Validated Y2H
25910212
Intra ALOX5 P09917 CEP57L1 Homo sapiens Q6P2R3
Y2H Bait-Prey Pool
25910212
Intra ALOX5 P09917 HSD17B1 Homo sapiens P14061
Validated Y2H
32296183
Intra ALOX5 P09917 HSD17B1 Homo sapiens P14061
Y2H Array
32296183
Intra ALOX5 P09917 HSD17B1 Homo sapiens P14061
Y2H Prey Pooling
32296183
Intra ALOX5 P09917 C10orf67 Homo sapiens Q8IYJ2-2
Y2H Array
32296183
Intra ALOX5 P09917 C10orf67 Homo sapiens Q8IYJ2-2
Y2H Prey Pooling
32296183
Intra ALOX5 P09917 C10orf67 Homo sapiens Q8IYJ2-2
Validated Y2H
32296183
Intra ALOX5 P09917 FGR Homo sapiens P09769
Protein Kinase Assay
24860872
Intra ALOX5 P09917 MEOX2 Homo sapiens Q6FHY5
Validated Y2H
32296183
Intra ALOX5 P09917 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra ALOX5 P09917 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra ALOX5 P09917 OOEP Homo sapiens A6NGQ2
Y2H Array
32296183
Intra ALOX5 P09917 OOEP Homo sapiens A6NGQ2
Y2H Prey Pooling
32296183
Intra ALOX5 P09917 MEOX1 Homo sapiens P50221
Y2H Prey Pooling
25416956
Intra ALOX5 P09917 MEOX1 Homo sapiens P50221
Y2H Array
25416956
Intra ALOX5 P09917 REL Homo sapiens Q04864
Y2H Array
25416956
Intra ALOX5 P09917 REL Homo sapiens Q04864
Y2H Prey Pooling
25416956
Intra ALOX5 P09917 TBC1D7 Homo sapiens Q9P0N9
Validated Y2H
32296183
Intra ALOX5 P09917 TBC1D7 Homo sapiens Q9P0N9
Y2H Prey Pooling
32296183
Intra ALOX5 P09917 TBC1D7 Homo sapiens Q9P0N9
Y2H Array
32296183
Intra ALOX5 P09917 PRKACA Homo sapiens P17612
Protein Kinase Assay
24860872
Intra ALOX5 P09917 YES1 Homo sapiens P07947
Protein Kinase Assay
24860872
Intra ALOX5 P09917 SPRED1 Homo sapiens Q7Z699
Validated Y2H
32814053
Intra ALOX5 P09917 SPRED1 Homo sapiens Q7Z699
Y2H Pooling
32814053
Intra ALOX5 P09917 SPRED1 Homo sapiens Q7Z699
Y2H Array
32814053
Intra ALOX5 P09917 SYCE1 Homo sapiens Q8N0S2
Y2H Array
25416956
Intra ALOX5 P09917 SYCE1 Homo sapiens Q8N0S2
Y2H Array
25910212
Intra ALOX5 P09917 SYCE1 Homo sapiens Q8N0S2
Y2H Bait-Prey Pool
25910212
Intra ALOX5 P09917 SYCE1 Homo sapiens Q8N0S2
Validated Y2H
25910212
Intra ALOX5 P09917 SYCE1 Homo sapiens Q8N0S2
Validated Y2H
25416956
Intra ALOX5 P09917 GATC Homo sapiens O43716
Y2H Array
32296183
Intra ALOX5 P09917 GATC Homo sapiens O43716
Y2H Prey Pooling
32296183
Intra ALOX5 P09917 CEP63 Homo sapiens Q96MT8
Y2H Prey Pooling
25416956
Intra ALOX5 P09917 CEP63 Homo sapiens Q96MT8
Y2H Array
25416956
Intra ALOX5 P09917 MAD1L1 Homo sapiens Q9Y6D9
Y2H Bait-Prey Pool
25910212
Intra ALOX5 P09917 MAD1L1 Homo sapiens Q9Y6D9
Validated Y2H
32296183
Intra ALOX5 P09917 MAD1L1 Homo sapiens Q9Y6D9
Y2H Prey Pooling
32296183
Intra ALOX5 P09917 MAD1L1 Homo sapiens Q9Y6D9
Y2H Array
25910212
Intra ALOX5 P09917 MAD1L1 Homo sapiens Q9Y6D9
Y2H Array
32296183
Intra ALOX5 P09917 MAD1L1 Homo sapiens Q9Y6D9
Y2H Array
25416956
Intra ALOX5 P09917 MAD1L1 Homo sapiens Q9Y6D9
Validated Y2H
25910212
Intra ALOX5 P09917 CCDC174 Homo sapiens Q6PII3
Validated Y2H
32296183
Intra ALOX5 P09917 CCDC174 Homo sapiens Q6PII3
Y2H Array
32296183
Intra ALOX5 P09917 CCDC174 Homo sapiens Q6PII3
Y2H Prey Pooling
32296183
Intra ALOX5 P09917 COTL1 Homo sapiens Q14019
Y2H
11297527
Intra ALOX5 P09917 COTL1 Homo sapiens Q14019
Pull Down
11297527
Intra ALOX5 P09917 COTL1 Homo sapiens Q14019
CoIP
11297527
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Cystic Fibrosis

Mucoviscidosis

CF

Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis

Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis

Cystic Fibrosis Lung Disease, Modifier Of

Cystic Fibrosis Of Pancreas

Fibrocystic Disease Of Pancreas

Cf - [Cystic Fibrosis]

Cystic Fibrosis Nos

Fibrocystic Disease

Fibrocystic Disease Of The Pancreas

Mucoviscidosis Of Pancreas

Nonproliferative Fibrocystic Disease

Pancreatic Cystic Fibrosis

Dermatitis

Eczema

Skin Inflammation

Inflammatory Dermatosis

Nasal Cavity Disease

Disorder Of Nasal Cavity

Exercise-Induced Bronchoconstriction

Exercise-Induced Asthma

Asthma Exercise-Induced

Myocardial Infarction

Heart Attack

Myocardial Infarction, Susceptibility To

Myocardial Infarction 1

Myocardial Infarction, Protection Against

Myocardial Infarction, Decreased Susceptibility To

Myocardial Infarction, Decreased

Myocardial Infarct

MCI1

Premature Myocardial Infarction

Myocardial Infarction, Susceptibility To, Type 1

Small Intestine Leiomyosarcoma

Leiomyosarcoma Of The Small Bowel

Smooth Muscle Connective Tissue Tumor

Leiomyosarcoma Of Small Intestine

Proteasome-Associated Autoinflammatory Syndrome 1

Jmp Syndrome

Nakajo-Nishimura Syndrome

Nkjo

Autoinflammation, Lipodystrophy, And Dermatosis Syndrome

Proteasome-Associated Autoinflammatory Syndrome 1 And Digenic Forms

Nakajo Syndrome

PRAAS1

Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy And Elevated Temperature Syndrome

Candle

Joint Contractures, Muscular Atrophy, Microcytic Anemia, And Panniculitis-Induced Lipodystrophy

Aldd

Joint Contractures - Muscle Atrophy - Microcytic Anemia - Panniculitis-Induced Lipodystrophy

Nakajo Nishimura Syndrome

Amyotrophy Fat Tissue Anomaly

Japanese Autoinflammatory Syndrome With Lipodystrophy

Jasl

Joint Contractures Muscular Atrophy Microcytic Anemia And Panniculitis-Induced Lipodystrophy

Nns

Nodular Erythema With Digital Changes

Secondary Hypertrophic Osteoperiostosis With Pernio

Inflammation

Cone-Rod Dystrophy 17

CORD17

Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory

Asthma

Chronic Obstructive Asthma

Asthma, Diminished Response To Antileukotriene Treatment In

Bronchial Hyperreactivity

Asthma, Susceptibility To

Asthma, Bronchial

Asthma, Protection Against

Asthma, Nocturnal, Susceptibility To

Nocturnal Asthma

Asthma-Related Traits

Asthma-Related Traits, Susceptibility To

Asthma, Nocturnal

Chronic Obstructive Asthma With Acute Exacerbation

Chronic Obstructive Asthma With Status Asthmaticus

Exercise Induced Asthma

Exercise-Induced Asthma

Bronchial Asthma

Asthma, Exercise-Induced

Idiosyncratic Asthma

Unspecified Asthma With Acute Exacerbation

Asthma, Unspecified, With Stated Status Asthmaticus

Status Asthmaticus Nos

Acute Severe Asthma

Acute Severe Bronchial Asthma

Status Asthma

Status Post Asthmaticus

Pancreatic Cancer

Pancreatic Carcinoma

Familial Pancreatic Carcinoma

Pancreatic Neoplasm

Carcinoma Of Pancreas

Pancreatic Carcinoma, Familial

Malignant Neoplasm Of Pancreas

Pancreatic Acinar Carcinoma

Pancreatic Tumor

Familial Pancreatic Cancer

Neoplasm Of The Pancreas

Pancreatic Carcinoma, Somatic

Pancreatic Cancer, Somatic

Ca Body Of Pancreas

Ca Head Of Pancreas

Ca Tail Of Pancreas

Malignant Neoplasm Of Body Of Pancreas

Malignant Neoplasm Of Head Of Pancreas

Malignant Neoplasm Of Tail Of Pancreas

Pancreas Neoplasm

Exocrine Cancer

Exocrine Pancreas Carcinoma

Hereditary Pancreatic Cancer

Hereditary Pancreatic Carcinoma

PNCA

Cancer Of The Pancreas

Pancreatic Cancer, Susceptibility To

Carcinoma Of Head Of Pancreas

Pancreatic Neoplasms

Pancreatic Tumors

Cancer, Pancreatic

Cancer Of Pancreas

Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site

Glioblastoma

Glioblastoma Multiforme

Gbm

Adult Glioblastoma Multiforme

Grade Iv Adult Astrocytic Tumor

Primary Glioblastoma Multiforme

Spongioblastoma Multiforme

Adult Glioblastoma

Primary Glioblastoma

Psoriasis
Cardiovascular System Disease

Abnormality Of The Cardiovascular System

Disease Of Subdivision Of Hemolymphoid System

Disorder Of Cardiovascular System

Cardiovascular Diseases

Cardiovascular Disease

Body Mass Index Quantitative Trait Locus 11

OBESITY

Obesity, Susceptibility To

Leanness, Inherited

Obesity, Susceptibility To, Bmiq11

Obesity, Mild, Early-Onset

Obesity, Association With

Obesity, Early-Onset, Susceptibility To

Obesity, Severe

Obesity, Severe, And Type Ii Diabetes

Obesity, Late-Onset

BMIQ11

Obesity Bmiq11

Obesity, Early-Onset

Obesity , Susceptibility To

Simple Obesity Nos

Excess Fat

Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified

Adiposis

Arthus Reaction

Arthus Phenomenon

Arthus Type Urticaria

Glomerulonephritis

Bright'S Disease

Adult Respiratory Distress Syndrome

Acute Respiratory Distress Syndrome

Ards

Non-Cardiogenic Pulmonary Edema

Acute Lung Injury

Respiratory Distress Syndrome, Adult

Shock Lung

Acute Respiratory Distress

Respiratory Distress Syndrome

Adult Rds

Ali

Increased-Permeability Pulmonary Edema

Stiff Lung

Respiratory Distress Syndrome Adult

Allergic Rhinitis

Hay Fever

Allergic Rhinitis, Susceptibility To

ALRH

Atopic Rhinitis

Seasonal Allergic Rhinitis

Non-Seasonal Allergic Rhinitis

Perenial Allergic Rhinitis

Pollenosis

Rhinitis Allergic Seasonal

Rhinitis, Allergic, Perennial

Allergic Rhinitis, Cause Unspecified

Pollinosis

Pollen Allergy

Allergy Nos Due To Pollen

Summer Catarrh

Other Seasonal Allergic Rhinitis

Panniculitis

Nodular Panniculitis

Acute Laryngopharyngitis

Pharyngolaryngitis

Laryngopharyngitis

Hypopharyngitis

Respiratory Failure

Acute Respiratory Failure

Chronic Respiratory Failure

Respiratory Insufficiency

Acute-On-Chronic Respiratory Failure

Acute And Chronic Respiratory Failure

Respiratory Insufficiency/Failure

Chronic Respiratory Disease

Respiratory Disease

Pulmonary Valve Insufficiency

Chronic Disease Of Respiratory System

Respiration Disorders

Respiratory Tract Diseases

Lung Failure Nos

Pulmonary Failure

Arf - [Acute Respiratory Failure]

Acute Respiratory Insufficiency

Acute Pulmonary Insufficiency

Acute Respiration Failure

Chronic Respiration Failure

Hypereosinophilic Syndrome

Eosinophilia

HES

Eosinophilic Leukocytosis

Hypereosinophilic Syndrome, Idiopathic

Idiopathic Hypereosinophilic Syndrome

Disseminated Eosinophilic Collagen Disease

Eosinophilic Disorder

Disorders With Increased Eosinophil Counts

Ichthyosis, Congenital, Autosomal Recessive 3

Autosomal Recessive Congenital Ichthyosis 3

ARCI3

Lamellar Ichthyosis 5

Collodion Baby, Self-Healing

Ichthyosis, Lamellar, 5, Formerly

Li5, Formerly

Li5

Self-Healing Collodion Baby

Ichthyosis, Congenital, Autosomal Recessive, Type 3

Aspirin-Induced Respiratory Disease

Aspirin-Sensitive Asthma

Chronic Urticaria

Urticaria Chronic

Chronic Spontaneous Urticaria

Chronic Ordinary Urticaria

Angioedema

Angioneurotic Oedema

Quincke'S Edema

Angioneurotic Edema

Giant Urticaria

Atherosclerosis Susceptibility

Atherosclerosis

Atherosclerosis, Susceptibility To

ATHS

Atherogenic Lipoprotein Phenotype

Alp

Arteriosclerosis

Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon

Allergic Asthma

Atopic Asthma

Extrinsic Asthma

Extrinsic Asthma With Acute Exacerbation

Extrinsic Asthma With Status Asthmaticus

Asthma Allergic

Atopic Asthma, Susceptibility To

Ige-Mediated Allergic Asthma

Allergen-Induced Asthma

Allergic Asthma Without Stated Status Asthmaticus

Predominantly Allergic Asthma Without Stated Status Asthmaticus

Predominantly Allergic Asthma

Allergic Asthma Nos

Catarrh With Asthma

Allergic Bronchitis Nos

Extrinsic Allergic Asthma

Predominantly Allergic Asthma With Stated Status Asthmaticus

Persistent Mild Asthma
Urticaria

Nettle Rash

Hives

Wheal

Urticaria Nos

Stroke, Ischemic

Cerebral Infarction

Stroke

Ischemic Stroke

Cerebrovascular Accident

Cerebral Infarction, Susceptibility To

Stroke, Ischemic, Susceptibility To

Cerebral Infarct

Ischemic Stroke, Susceptibility To

Stroke, Susceptibility To

Cva - Cerebral Infarction

ISCHSTR

Ischemic Cerebrovascular Accident

Pleurisy
Alzheimer Disease, Familial, 1

Alzheimer Disease

Alzheimer'S Disease

Presenile And Senile Dementia

AD1

Alzheimer Disease, Susceptibility To

Alzheimer Disease, Late-Onset, Susceptibility To

Alzheimer Disease 1, Familial

AD

Familial Alzheimer Disease

Alzheimer Disease, Late-Onset

Alzheimers Dementia

Alzheimer Dementia

Alzheimer Sclerosis

Alzheimer Syndrome

Alzheimer-Type Dementia

Dat

Primary Senile Degenerative Dementia

Sdat

Alzheimer Disease 1

Autosomal Dominant Alzheimer Disease

Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy

Late Onset Alzheimer Disease

Alzheimers Disease

Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy

Late-Onset Alzheimers Disease

Alzheimer'S Disease Pathway Kegg

Dementia Due To Alzheimer'S Disease

Alzheimer Disease Type 1

Alzheimers

Allergic Disease

Hypersensitivity

Allergic Hypersensitivity Disease

Allergic Condition

Allergic Reaction

Allergic Disposition

Interstitial Lung Disease 2

Idiopathic Pulmonary Fibrosis

Ipf

Fibrocystic Pulmonary Dysplasia

Pulmonary Fibrosis, Idiopathic

Pulmonary Fibrosis, Idiopathic, Susceptibility To

ILD2

Idiopathic Pulmonary Fibrosis, Familial

Fibrosing Alveolitis, Cryptogenic

Uip

Cryptogenic Fibrosing Alveolitis

Fibrosing Alveolitis

Interstitial Pneumonitis, Usual

Familial Idiopathic Pulmonary Fibrosis

Idiopathic Fibrosing Alveolitis, Chronic Form

Usual Interstitial Pneumonia

Fibrosing Alveolitis Cryptogenic

Hamman-Rich Disease

Idiopathic Pulmonary Fibrosis Familial

Interstitial Pneumonitis Usual

Fibrosis Idiopathic Pulmonary

Fibrosis, Pulmonary, Idiopathic

Hamman-Rich Syndrome

Chronic Idiopathic Pulmonary Fibrosis

Acute Interstitial Pneumonia

Interstitial Pulmonary Fibrosis

Ipf - [Idiopathic Pulmonary Fibrosis]

Idiopathic Lung Fibrosis

Fibrosing Lung Disease

Pulmonary Fibrosis Nos

Fibrosing Pneumonitis

Bronchial Disease

Bronchial Diseases

Bronchial Disorders

Bronchial Spasm

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus ALOX5 VGNC VGNC:59757
Rattus norvegicus ALOX5 RGD RGD:2096
Macaca mulatta ALOX5 VGNC VGNC:69798
Bos taurus ALOX5 VGNC VGNC:25844
Mus musculus ALOX5 MGD MGI:87999
Canis familiaris ALOX5 VGNC VGNC:37813