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  2. NUTM1 - NUT midline carcinoma family member 1 Gene

NUTM1 - NUT midline carcinoma family member 1 Gene

中文名称:NUT 中线癌家族成员 1

种属: Homo sapiens

同用名: NUT; FAM22H; C15orf55

基因 ID: 256646 | 基因类型: protein coding

关于 NUTM1

Cytogenetic location: 15q14 Genomic coordinates (GRCh38): 15:34,343,315-34,357,735 (from NCBI)

This gene has 4 transcripts (splice variants), 96 orthologues, 6 paralogues and is associated with 71 phenotypes. Restricted expression toward testis (RPKM 8.8).

功能概要

预测位于细胞质和细胞核中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

NUTM1 基因产物(3)

mRNA Protein Name
NM_001284292.2 NP_001271221.2 NUT family member 1 isoform 1
NM_001284293.2 NP_001271222.2 NUT family member 1 isoform 2
NM_175741.3 NP_786883.2 NUT family member 1 isoform 3
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

NUTM1 蛋白结构

NUT

NUT: NUT protein (9 - 332)

(344 - 485)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1132 a.a.
蛋白主名 其他名称

NUT family member 1

NAP1L4/NUTM1D fusion

NUTM1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra NUTM1 Q86Y26 TP53BP2 Homo sapiens Q13625-3
Validated Y2H
25416956
Intra NUTM1 Q86Y26 TP53BP2 Homo sapiens Q13625-3
Y2H Array
25416956
Intra NUTM1 Q86Y26 CCHCR1 Homo sapiens Q8TD31-3
Y2H Array
25416956
Intra NUTM1 Q86Y26 CCHCR1 Homo sapiens Q8TD31-3
Y2H Prey Pooling
25416956
Intra NUTM1 Q86Y26 P4HA3 Homo sapiens Q7Z4N8
Y2H Prey Pooling
25416956
Intra NUTM1 Q86Y26 P4HA3 Homo sapiens Q7Z4N8
Y2H Array
31515488
Intra NUTM1 Q86Y26 ZNF277 Homo sapiens Q8WWA6
Validated Y2H
25416956
Intra NUTM1 Q86Y26 ZNF277 Homo sapiens Q8WWA6
Y2H Array
25416956
Intra NUTM1 Q86Y26 MORN4 Homo sapiens Q8NDC4
Validated Y2H
25416956
Intra NUTM1 Q86Y26 MORN4 Homo sapiens Q8NDC4
Y2H Prey Pooling
25416956
Intra NUTM1 Q86Y26 MORN4 Homo sapiens Q8NDC4
Y2H Array
25416956
Intra NUTM1 Q86Y26 q9h641_human Homo sapiens Q9H641
Validated Y2H
25416956
Intra NUTM1 Q86Y26 SAMD4A Homo sapiens Q9UPU9
Y2H Prey Pooling
25416956
Intra NUTM1 Q86Y26 PSME4 Homo sapiens Q14997
Y2H Prey Pooling
25416956
Intra NUTM1 Q86Y26 PSME4 Homo sapiens Q14997
Y2H Array
25416956
Intra NUTM1 Q86Y26 PRKAA2 Homo sapiens P54646
Y2H Array
25416956
Intra NUTM1 Q86Y26 PRKAA2 Homo sapiens P54646
Y2H Prey Pooling
25416956
Intra NUTM1 Q86Y26 NEBL Homo sapiens O76041
Y2H Prey Pooling
25416956
Intra NUTM1 Q86Y26 FAM161A Homo sapiens Q3B820
Y2H Prey Pooling
25416956
Intra NUTM1 Q86Y26 FAM161A Homo sapiens Q3B820
Validated Y2H
25416956
Intra NUTM1 Q86Y26 FAM161A Homo sapiens Q3B820
Y2H Array
25416956
Intra NUTM1 Q86Y26 HSPBAP1 Homo sapiens Q96EW2
Validated Y2H
25416956
Intra NUTM1 Q86Y26 HSPBAP1 Homo sapiens Q96EW2
Y2H Prey Pooling
25416956
Intra NUTM1 Q86Y26 LMO2 Homo sapiens P25791
Validated Y2H
25416956
Intra NUTM1 Q86Y26 LMO2 Homo sapiens P25791
Y2H Array
25416956
Intra NUTM1 Q86Y26 KANSL1 Homo sapiens Q7Z3B3
Y2H Prey Pooling
25416956
Intra NUTM1 Q86Y26 LMO3 Homo sapiens Q8TAP4
Y2H Prey Pooling
25416956
Intra NUTM1 Q86Y26 IFIT2 Homo sapiens Q8IZ03
Validated Y2H
25416956
Intra NUTM1 Q86Y26 IFIT2 Homo sapiens Q8IZ03
Y2H Array
25416956
Intra NUTM1 Q86Y26 SH2D4A Homo sapiens Q9H788
Validated Y2H
25416956
Intra NUTM1 Q86Y26 ZMYND10 Homo sapiens O75800
Y2H Array
25416956
Intra NUTM1 Q86Y26 ALOX5 Homo sapiens P09917
Y2H Array
31515488
Intra NUTM1 Q86Y26 ALOX5 Homo sapiens P09917
Validated Y2H
25416956
Intra NUTM1 Q86Y26 ALOX5 Homo sapiens P09917
Y2H Array
25416956
Intra NUTM1 Q86Y26 LHX8 Homo sapiens Q68G74
Validated Y2H
25416956
Intra NUTM1 Q86Y26 LHX8 Homo sapiens Q68G74
Y2H Array
25416956
Intra NUTM1 Q86Y26 LMO1 Homo sapiens P25800
Y2H Array
25416956
Intra NUTM1 Q86Y26 RIC8A Homo sapiens Q9NPQ8-4
Y2H Array
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Spindle Cell Sarcoma

Sarcoma

Sarcoma Spindle Cell

Sarcoma, Spindle Cell

Sarcoma - Category

Nut Midline Carcinoma

Nuclear Protein In Testis Midline Carcinoma

Nmc

Nasal Cavity Cancer

Nasal Cavity Carcinoma

Malignant Neoplasm Of Nasal Cavities

Malignant Tumor Of The Nasal Cavity

Cancer Of Nasal Cavity

Carcinoma Of Nasal Cavity

Malignant Neoplasm Of Nasal Cavity

Neoplasm Of Nasal Cavity

Sinonasal Undifferentiated Carcinoma

Highly Aggressive Undifferentiated Carcinoma Of The Nasal Cavity And Paranasal Sinuses

Snuc

Paranasal Sinus Cancer

Paranasal Sinus Adenoid Cystic Carcinoma

Paranasal Sinus Mucoepidermoid Carcinoma

Paranasal Sinus Squamous Cell Carcinoma

Paranasal Sinus Neoplasms

Adenoid Cystic Carcinoma Of Accessory Sinus

Adenoid Cystic Carcinoma Of Paranasal Sinus

Epidermoid Carcinoma Of The Paranasal Sinus

Mucoepidermoid Carcinoma Of Accessory Sinus

Paranasal Sinus Adenocarcinoma

Squamous Cell Carcinoma Of Paranasal Sinus

Paranasal Sinus Neoplasm

Adenocarcinoma Of Accessory Sinus

Eccrine Sweat Gland Cancer

Malignant Eccrine Skin Neoplasm

Malignant Eccrine Tumor

Mediastinum Sarcoma

Sarcoma Of Mediastinum

Laryngeal Neuroendocrine Tumor

Laryngeal Neuroendocrine Tumour

Neuroendocrine Tumor Of Larynx

Neuroendocrine Tumour Of Larynx

Neuroendocrine Neoplasm Of Larynx

Internal Auditory Canal Lipoma

Lipoma Of The Internal Auditory Canal

Inner Ear Lipoma

Eccrine Acrospiroma

Acrospiroma

Poroma

Eccrine Hidradenoma

Eccrine Hidradenoma Of Skin

Hidradenoma

Adenoma, Sweat Gland

Benign Neoplasm Of Sweat Gland

Eccrine Poroma

Eccrine Sweat Gland Neoplasm

Eccrine Skin Neoplasm

Eccrine Tumor

Eccrine Neoplasm

Malignant Eccrine Neoplasm

Ethmoid Sinus Cancer

Malignant Neoplasm Of Ethmoidal Sinus

Malignant Tumor Of Ethmoid Sinus

Malignant Tumor Of Ethmoidal Sinus

Neoplasm Of Ethmoidal Sinus

Schneiderian Carcinoma

Cylindrical Cell Carcinoma

Nasal Cavity Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Nasal Cavity

Squamous Cell Carcinoma Of The Nasal Cavity

Basaloid Squamous Cell Carcinoma

Basaloid Carcinoma

Eccrine Porocarcinoma

Porocarcinoma

Eccrine Porocarcinoma Of Skin

Malignant Eccrine Poroma

Extragonadal Nonseminomatous Germ Cell Tumor

Primary Malignant Extragonadal Nonseminoma

Malignant Extragonadal Non-Seminomatous Germ Cell Tumor

Lymphoepithelioma-Like Thymic Carcinoma

Lymphoepithelioma-Like Carcinoma Of The Thymus

Thymic Lymphoepithelioma-Like Carcinoma

Mucocele Of Salivary Gland

Ranula

Salivary Cyst

Salivary Gland Mucocele

Mucous Retention Cyst Of Salivary Gland

Retention Cyst Of Salivary Gland

Sialocele

Cyst Of Salivary Gland Or Duct

Extravasation Cyst Of Salivary Gland

Keratinizing Squamous Cell Carcinoma

Squamous Cell Carcinoma, Keratinizing

Keratinizing Epidermoid Carcinoma

Lymphoepithelioma-Like Carcinoma

Lymphoepithelial Carcinoma

Nasopharyngeal Type Undifferentiated Carcinoma

Malignant Olfactory Nerve Neoplasm

Malignant Olfactory Nerve Tumor

Malignant Tumor Of Olfactory Nerve

Primary Malignant Neoplasm Of Olfactory Nerve

Smarca4-Deficient Sarcoma Of Thorax

Smarca4-Dts

Smarca4-Deficient Thoracic Sarcoma

Cranial Nerve Malignant Neoplasm

Cranial Nerve Neoplasms

Malignant Neoplasm Of Cranial Nerve

Malignant Tumor Of Cranial Nerve

Malignant Tumor Of The Cranial Nerve

Thymus Adenocarcinoma

Adenocarcinoma Of The Thymus

Thymic Adenocarcinoma

Bladder Sarcoma

Sarcoma Of Bladder

Sarcoma Of The Urinary Bladder

Thymus Large Cell Carcinoma

Large Cell Carcinoma Of The Thymus

Thymic Large Cell Neuroendocrine Carcinoma

Salivary Gland Carcinoma

Salivary Gland Cancer

Malignant Neoplasm Of Salivary Gland

Salivary Gland Neoplasms

Mediastinal Cancer

Mediastinal Neoplasms

Mediastinal Tumor

Mediastinum Cancer

Neoplasm Of Mediastinum

Tumour Of Mediastinum

Malignant Tumor Of Mediastinum

Cns Neuroblastoma With Foxr2 Activation

Central Nervous System Neuroblastoma With Foxr2 Activation

Cns Nb-Foxr2

Cns Neuroblastoma, Foxr2-Activated

Myoepithelial Carcinoma

Malignant Myoepithelioma

Myoepithelioma Carcinoma

Central Nervous System Neuroblastoma
Sweat Gland Benign Neoplasm

Neoplasm Of Sweat Gland

Sweat Gland Tumor

Tumor Of The Sweat Gland

Sweat Gland Neoplasms

Sweat Gland Neoplasm

Olfactory Neuroblastoma

Esthesioneuroblastoma

Asthesioneuroblastoma

Esthesioneuroepithelioma

Olfactory Esthesioneuroblastoma

Paranasal Sinus Olfactory Neuroblastoma

Esthesioneuroblastoma, Olfactory

Esthesioneuroblastoma Of Nasal Cavity

Endobronchial Lipoma
Central Nervous System Germ Cell Tumor

Central Nervous System Germ Cell Tumour

Germ Cell Tumor Of The Cns

Germ Cell Tumour Of The Cns

Thymic Carcinoma

Malignant Thymoma

Thymoma, Malignant

Hidradenoma

Adenoma, Sweat Gland

Hidradenoma Of Skin

Sweat Gland Adenoma

Syringoadenoma

Eccrine Acrospiroma

Benign Neoplasm Of Sweat Gland

Paranasal Sinus Disease

Paranasal Sinus Diseases

Disorder Of Nasal Sinus

Sweat Gland Disease

Sweat Gland Diseases

Tonsil Cancer

Tonsillar Neoplasms

Malignant Neoplasm Of Faucial Tonsil

Malignant Neoplasm Of Palatine Tonsil

Malignant Neoplasm Of Tonsil, Faucial

Malignant Tonsillar Tumor

Malignant Tumor Of Tonsil

Tonsillar Carcinoma

Malignant Neoplasm Tonsil

Ewing Sarcoma

Neuroepithelioma

Ewing'S Tumor

Primitive Neuroectodermal Tumor

Ewings Sarcoma

Ewing'S Sarcoma

Peripheral Neuroepithelioma

ES

Ewings Sarcoma-Primitive Neuroectodermal Tumor

Localized Peripheral Primitive Neuroectodermal Tumor

Peripheral Primitive Neuroectodermal Tumor

Ewing Tumor

Sarcoma, Ewing'S

Ewing Family Of Tumors

Extraosseous Ewing Tumor

Askin Tumor

Ewing'S Family Localized Tumor

Ewing'S Sarcoma/Peripheral Primitive Neuroectodermal Tumor

Localized Ewing Sarcoma

Localized Ewing'S Sarcoma

Localized Ewing'S Sarcoma/Peripheral Primitive Neuroectodermal Tumor

Localized Ewing'S Tumor

Pnet Of Thoracopulmonary Region

Tumor Of The Ewing Family

Skeletal Ewing Sarcoma

Osseous Ewing Sarcoma

Ppnet

Peripheral Pnet

Extraskeletal Ewing Sarcoma

Eoe

Extraosseous Ewing Sarcoma

Extraskeletal Ewing Tumor

Esft

Ewing Sarcoma Family Of Tumors

Pne

Pnet

Pnet Of The Chest Wall

Sarcoma, Ewing

Neuroectodermal Tumors, Primitive, Peripheral

Neuroectodermal Tumor, Primitive

Disorder Of Eye

Askin'S Tumor

Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

Neuroepithelioma, Peripheral

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus NUTM1 RGD RGD:1564529
Mus musculus NUTM1 MGD MGI:2661384