HSPBAP1 - HSPB1 associated protein 1 Gene

中文名称：HSPB1 相关蛋白 1

种属: Homo sapiens

同用名: PASS1

基因 ID: 79663 | 基因类型: protein coding

关于 HSPBAP1

Cytogenetic location: 3q21.1 Genomic coordinates (GRCh38): 3:122,739,999-122,793,831 (from NCBI)

This gene has 6 transcripts (splice variants), 226 orthologues, 4 paralogues and is associated with 1 phenotype. Ubiquitous expression in testis (RPKM 3.1), spleen (RPKM 2.7) and 25 other tissues.

功能概要

该基因编码的蛋白质可与一种小型热休克蛋白结合，特别是 hsp27。 Hsp27 参与细胞生长和分化。这种编码的蛋白质被发现在顽固性癫痫患者中异常表达，尽管大脑功能如何受到影响仍然未知。[RefSeq 提供，2011 年 9 月]

This gene encodes a protein that binds to one of the small heat shock proteins, specifically hsp27. Hsp27 is involved with cell growth and differentiation. This encoded protein was found to be abnormally expressed in patients with intractable epilepsy, although how brain function is affected remains unknown. [provided by RefSeq, Sep 2011]

HSPBAP1 基因产物(2)

mRNA	Protein	Name
NM_001320728.2	NP_001307657.1	HSPB1-associated protein 1 isoform 2
NM_024610.6	NP_078886.2	HSPB1-associated protein 1 isoform 1

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	24981860	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

HSPBAP1 蛋白结构

Cupin_8

0
100
200
300
400
488 a.a.

蛋白主名

其他名称

HSPB1-associated protein 1

27 kDa heat shock protein-associated protein 1

HSPBAP1 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	HSPBAP1	Q96EW2	NUTM1	Homo sapiens	Q86Y26	Y2H Array	25416956
种属内	HSPBAP1	Q96EW2	ABHD10	Homo sapiens	Q9NUJ1	Anti Tag CoIP	33961781
种属内	HSPBAP1	Q96EW2	ARHGEF5	Homo sapiens	Q12774	Validated Y2H	25416956
种属内	HSPBAP1	Q96EW2	ARHGEF5	Homo sapiens	Q12774	Y2H Prey Pooling	25416956
种属内	HSPBAP1	Q96EW2	NCALD	Homo sapiens	P61601	Anti Tag CoIP	33961781
种属内	HSPBAP1	Q96EW2	NCALD	Homo sapiens	P61601	Anti Tag CoIP	28514442

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Renal Cell Carcinoma, Nonpapillary

Renal Cell Carcinoma	RCC
Nonpapillary Renal Cell Carcinoma	Clear Cell Renal Cell Carcinoma
Hypernephroma	Adenocarcinoma Of Kidney
Renal Carcinoma, Chromophobe, Somatic	Clear Cell Carcinoma Of Kidney
Clear-Cell Metastatic Renal Cell Carcinoma	Clear Cell Renal Carcinoma
Renal Cell Carcinoma, Somatic	Conventional Renal Cell Carcinoma
Conventional Renal Cell Carcinoma	Renal Clear Cell Carcinoma
Ccrcc	Hereditary Clear Cell Renal Cell Carcinoma
Carcinoma, Renal Cell	Renal Cell Carcinoma, Clear Cell, Somatic
Renal Cell Carcinoma, Clear Cell	Clear Cell Kidney Carcinoma
Clear Cell Rcc	Cystic-Multilocular Variant
Clear Cell Renal Cell Adenocarcinoma	Hereditary Clear Cell Renal Cell Adenocarcinoma
Common Renal Cell Carcinoma	Crcc
Renal Cell Carcinoma Non-Papillary	Carcinoma Renal Cell
Renal Cell Cancer	Carcinoma, Renal Cell, Nonpapillary

Epilepsy

Epilepsy Syndrome	Epileptic Syndrome
Epilepsies	Symptomatic Epilepsies
Post Traumatic Epilepsy	Traumatic Epilepsy
Traumatic Epileptic	Epilepsy Due To Hippocampal Sclerosis
Epilepsy With Ammon'S Horn Sclerosis	Epilepsy Due To Cortical Dysplasia
Epilepsy Due To Neuronal Migration Disorders

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS06445	HSPBAP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	HSPBAP1	MGD	MGI:1913917
Rattus norvegicus	HSPBAP1	RGD	RGD:620870
Felis catus	HSPBAP1	VGNC	VGNC:97459
Bos taurus	HSPBAP1	VGNC	VGNC:29987
Macaca mulatta	HSPBAP1	VGNC	VGNC:81420
Canis familiaris	HSPBAP1	VGNC	VGNC:41819

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

HSPBAP1 - HSPB1 associated protein 1 Gene

关于 HSPBAP1

功能概要

HSPBAP1 基因产物(2)

HSPBAP1 蛋白结构

HSPBAP1 蛋白互作信息

关联疾病

直系同源

热门区域

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HSPBAP1 - HSPB1 associated protein 1 Gene

关于 HSPBAP1

功能概要

HSPBAP1 基因产物(2)

HSPBAP1 蛋白结构

HSPBAP1 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z