2. Gene
  3. HSPBAP1 - HSPB1 associated protein 1 Gene

HSPBAP1 - HSPB1 associated protein 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：HSPB1 相关蛋白 1

种属: Homo sapiens

同用名: PASS1

基因 ID: 79663 | 基因类型: protein coding

关于 HSPBAP1

Cytogenetic location: 3q21.1 Genomic coordinates (GRCh38): 3:122,739,999-122,793,831 (from NCBI)

This gene has 6 transcripts (splice variants), 226 orthologues, 4 paralogues and is associated with 1 phenotype. Ubiquitous expression in testis (RPKM 3.1), spleen (RPKM 2.7) and 25 other tissues.

功能概要

该基因编码的蛋白质可与一种小型热休克蛋白结合，特别是 hsp27。 Hsp27 参与细胞生长和分化。这种编码的蛋白质被发现在顽固性癫痫患者中异常表达，尽管大脑功能如何受到影响仍然未知。[RefSeq 提供，2011 年 9 月]

This gene encodes a protein that binds to one of the small heat shock proteins, specifically hsp27. Hsp27 is involved with cell growth and differentiation. This encoded protein was found to be abnormally expressed in patients with intractable epilepsy, although how brain function is affected remains unknown. [provided by RefSeq, Sep 2011]

HSPBAP1 基因产物(2)

mRNA Protein Name
NM_001320728.2 NP_001307657.1 HSPB1-associated protein 1 isoform 2
NM_024610.6 NP_078886.2 HSPB1-associated protein 1 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
24981860 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

HSPBAP1 蛋白结构

Cupin_8

Cupin_8: Cupin-like domain (37 - 274)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 488 a.a.
蛋白主名 其他名称

HSPB1-associated protein 1

27 kDa heat shock protein-associated protein 1

HSPBAP1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra HSPBAP1 Q96EW2 NUTM1 Homo sapiens Q86Y26
Y2H Array
25416956
Intra HSPBAP1 Q96EW2 ABHD10 Homo sapiens Q9NUJ1
Anti Tag CoIP
33961781
Intra HSPBAP1 Q96EW2 ARHGEF5 Homo sapiens Q12774
Validated Y2H
25416956
Intra HSPBAP1 Q96EW2 ARHGEF5 Homo sapiens Q12774
Y2H Prey Pooling
25416956
Intra HSPBAP1 Q96EW2 NCALD Homo sapiens P61601
Anti Tag CoIP
33961781
Intra HSPBAP1 Q96EW2 NCALD Homo sapiens P61601
Anti Tag CoIP
28514442
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Renal Cell Carcinoma, Nonpapillary

Renal Cell Carcinoma

RCC

Nonpapillary Renal Cell Carcinoma

Clear Cell Renal Cell Carcinoma

Hypernephroma

Adenocarcinoma Of Kidney

Renal Carcinoma, Chromophobe, Somatic

Clear Cell Carcinoma Of Kidney

Clear-Cell Metastatic Renal Cell Carcinoma

Clear Cell Renal Carcinoma

Renal Cell Carcinoma, Somatic

Conventional Renal Cell Carcinoma

Conventional Renal Cell Carcinoma

Renal Clear Cell Carcinoma

Ccrcc

Hereditary Clear Cell Renal Cell Carcinoma

Carcinoma, Renal Cell

Renal Cell Carcinoma, Clear Cell, Somatic

Renal Cell Carcinoma, Clear Cell

Clear Cell Kidney Carcinoma

Clear Cell Rcc

Cystic-Multilocular Variant

Clear Cell Renal Cell Adenocarcinoma

Hereditary Clear Cell Renal Cell Adenocarcinoma

Common Renal Cell Carcinoma

Crcc

Renal Cell Carcinoma Non-Papillary

Carcinoma Renal Cell

Renal Cell Cancer

Carcinoma, Renal Cell, Nonpapillary
Epilepsy

Epilepsy Syndrome

Epileptic Syndrome

Epilepsies

Symptomatic Epilepsies

Post Traumatic Epilepsy

Traumatic Epilepsy

Traumatic Epileptic

Epilepsy Due To Hippocampal Sclerosis

Epilepsy With Ammon'S Horn Sclerosis

Epilepsy Due To Cortical Dysplasia

Epilepsy Due To Neuronal Migration Disorders
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06445 HSPBAP1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus HSPBAP1 MGD MGI:1913917
Rattus norvegicus HSPBAP1 RGD RGD:620870
Felis catus HSPBAP1 VGNC VGNC:97459
Bos taurus HSPBAP1 VGNC VGNC:29987
Macaca mulatta HSPBAP1 VGNC VGNC:81420
Canis familiaris HSPBAP1 VGNC VGNC:41819
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