1. Gene
  2. NR2C2AP - nuclear receptor 2C2 associated protein Gene

NR2C2AP - nuclear receptor 2C2 associated protein Gene

中文名称:核受体 2C2 相关蛋白

种属: Homo sapiens

同用名: TRA16

基因 ID: 126382 | 基因类型: protein coding

关于 NR2C2AP

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:19,201,409-19,203,414 (from NCBI)

This gene has 7 transcripts (splice variants) and 194 orthologues. Ubiquitous expression in ovary (RPKM 9.3), skin (RPKM 8.7) and 25 other tissues.

功能概要

位于核质中。 [由基因组资源联盟提供,2022 年 4 月]

Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

NR2C2AP 基因产物(2)

mRNA Protein Name
NM_001300945.2 NP_001287874.1 nuclear receptor 2C2-associated protein isoform 1
NM_176880.6 NP_795361.1 nuclear receptor 2C2-associated protein isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12486131 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

NR2C2AP 蛋白结构

F5_F8_type_C

F5_F8_type_C: F5/8 type C domain (15 - 99)

  • 0
  • 100
  • 139 a.a.
蛋白主名 其他名称

nuclear receptor 2C2-associated protein

TR4 orphan receptor associated protein TRA16

NR2C2AP 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra NR2C2AP Q86WQ0 REL Homo sapiens Q04864-2
Y2H Prey Pooling
32296183
Intra NR2C2AP Q86WQ0 REL Homo sapiens Q04864-2
Y2H Array
32296183
Intra NR2C2AP Q86WQ0 TEPSIN Homo sapiens Q96N21
Validated Y2H
32296183
Intra NR2C2AP Q86WQ0 TEPSIN Homo sapiens Q96N21
Y2H Array
32296183
Intra NR2C2AP Q86WQ0 TEPSIN Homo sapiens Q96N21
Y2H Prey Pooling
32296183
Intra NR2C2AP Q86WQ0 VPS52 Homo sapiens Q8N1B4
Validated Y2H
32296183
Intra NR2C2AP Q86WQ0 VPS52 Homo sapiens Q8N1B4
Y2H Array
32296183
Intra NR2C2AP Q86WQ0 VPS52 Homo sapiens Q8N1B4
Y2H Prey Pooling
32296183
Intra NR2C2AP Q86WQ0 REL Homo sapiens Q04864
Y2H Prey Pooling
25416956
Intra NR2C2AP Q86WQ0 TCF4 Homo sapiens P15884
Validated Y2H
25416956
Intra NR2C2AP Q86WQ0 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
Intra NR2C2AP Q86WQ0 DDIT4L Homo sapiens Q96D03
Validated Y2H
32296183
Intra NR2C2AP Q86WQ0 DDIT4L Homo sapiens Q96D03
Y2H Array
32296183
Intra NR2C2AP Q86WQ0 SLC16A3 Homo sapiens O15427
Y2H Prey Pooling
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Bare Lymphocyte Syndrome, Type Ii

Mhc Class Ii Deficiency

Bare Lymphocyte Syndrome

Major Histocompatibility Complex Class Ii Deficiency

Bare Lymphocyte Syndrome 2

Bare Lymphocyte Syndrome Type 2

Severe Combined Immunodeficiency, Hla Class Ii-Negative

Bare Lymphocyte Syndrome, Type Ii, Complementation Group C

Bare Lymphocyte Syndrome, Type Ii, Complementation Group D

Bare Lymphocyte Syndrome Type Ii

Scid, Hla Class Ii-Negative

Bare Lymphocyte Syndrome, Type Ii, Complementation Group A

Bare Lymphocyte Syndrome, Type Ii, Complementation Group B

Scid Due To Absent Class Ii Hla Antigens

Hla Class 1 Deficiency

Scid, Hla Class 2-Negative

Bls Type Ii

Bare Lymphocyte Syndrome Type 2, Complementation Group A

Bare Lymphocyte Syndrome Type 2, Complementation Group E

Severe Combined Immunodeficiency

Bls, Type Ii

Bls

Bare Lymphocyte Syndrome, Type Ii, Complementation Group E

Blsii

Bls Type 1

Bls 2

Scid Due To Absence Of Class Ii Hla Antigens

Severe Combined Immunodeficiency Due To Absent Class Ii Human Leukocyte Antigens

Immunodeficiency By Defective Expression Of Mhc Class Ii

BLS2

Bare Lymphocyte Syndrome Type Ii Complementation Group A

Bare Lymphocyte Syndrome Type Ii Complementation Group B

Bare Lymphocyte Syndrome Type Ii Complementation Group C

Bare Lymphocyte Syndrome Type Ii Complementation Group D

Bare Lymphocyte Syndrome Type Ii Complementation Group E

Bls Ii

Hereditary Mhc Class Ii Deficiency

Hla Class Ii Deficient Combined Immunodeficiency

Mhc-Ii Deficiency

Scid Hla Class Ii-Negative

Severe Combined Immunodeficiency Hla Class Ii-Negative

Bl-2

Immunodeficiency By Defective Expression Of Hla Class 2

Hla Class 2-Negative Severe Combined Immunodeficiency

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus NR2C2AP VGNC VGNC:32237
Macaca mulatta NR2C2AP VGNC VGNC:75495
Felis catus NR2C2AP VGNC VGNC:63877
Rattus norvegicus NR2C2AP RGD RGD:1561190
Mus musculus NR2C2AP MGD MGI:1922942
Canis familiaris NR2C2AP VGNC VGNC:43948