1. Gene
  2. RHOV - ras homolog family member V Gene

RHOV - ras homolog family member V Gene

中文名称:ras 同系物家族成员 V

种属: Homo sapiens

同用名: CHP; ARHV; WRCH2

基因 ID: 171177 | 基因类型: protein coding

关于 RHOV

Cytogenetic location: 15q15.1 Genomic coordinates (GRCh38): 15:40,872,214-40,874,234 (from NCBI)

This gene has 1 transcript (splice variant), 241 orthologues and 22 paralogues. Biased expression in esophagus (RPKM 34.6), skin (RPKM 27.2) and 5 other tissues.

功能概要

预测启用 GTP 结合活动和 GTPase 活动。预计参与多个过程,包括 Cdc42 蛋白信号转导;细胞投影组件;和胞吞作用。预测位于质膜中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in several processes, including Cdc42 protein signal transduction; cell projection assembly; and endocytosis. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

RHOV 基因产物(1)

mRNA Protein Name
NM_133639.4 NP_598378.3 rho-related GTP-binding protein RhoV
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16752908 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

RHOV 蛋白结构

Ras

Ras: Ras family (33 - 203)

  • 0
  • 100
  • 200
  • 236 a.a.
蛋白主名 其他名称

rho-related GTP-binding protein RhoV

CDC42-like GTPase 2

RHOV 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
RHOV Q96L33 PAK6 Homo sapiens Q9NQU5
Validated Y2H
32296183
种属内
RHOV Q96L33 NCK2 Homo sapiens O43639
ITC
16752908
种属内
RHOV Q96L33 NCK2 Homo sapiens O43639
NMR
16752908
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Ascaridiasis

Ascariasis

Toxic Megacolon

Megacolon, Toxic

Toxic Dilatation Of Colon

Toxic Functional Megacolon

Deafness, Autosomal Recessive 104

DFNB104

Autosomal Recessive Nonsyndromic Deafness 104

Autosomal Recessive Deafness 104

Deafness, Autosomal Recessive, 104

Deafness, Autosomal Recessive, Type 104

Deafness, Autosomal Dominant 1, With Or Without Thrombocytopenia

Konigsmark Syndrome

DFNA1

Autosomal Dominant Nonsyndromic Deafness 1

Lfhl1

Deafness, Autosomal Dominant 1

Autosomal Dominant Deafness 1

Autosomal Dominant Deafness 1, With Or Without Thrombocytopenia

Hereditary Low Frequency Hearing Loss 1

Diaph1-Related Sensorineural Hearing Loss-Thrombocytopenia Syndrome

Diaph1-Related Sensorineural Deafness-Thrombocytopenia Syndrome

Hereditary Low-Frequency Hearing Loss

Hereditary Low-Frequency Sensorineural Hearing Loss

Lfsnhl1

Non-Syndromic Neurosensory Deafness Autosomal Dominant Type 1

Non-Syndromic Sensorineural Deafness Autosomal Dominant Type 1

Deafness, Autosomal Dominant, Type 1

Clostridium Difficile Colitis

Pseudomembranous Colitis

Colitis Pseudomembranous

Enterocolitis, Pseudomembranous

Pseudomembranous Enterocolitis

Clostridium Difficile Infection

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus RHOV VGNC VGNC:55140
Mus musculus RHOV MGD MGI:2444227
Rattus norvegicus RHOV RGD RGD:628824
Canis familiaris RHOV VGNC VGNC:45566
Felis catus RHOV VGNC VGNC:64619