2. Gene
  3. GABPB2 - GA binding protein transcription factor subunit beta 2 Gene

GABPB2 - GA binding protein transcription factor subunit beta 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：GA 结合蛋白转录因子亚基β2

种属: Homo sapiens

同用名: GABPB-2

基因 ID: 126626 | 基因类型: protein coding

关于 GABPB2

This gene has 6 transcripts (splice variants), 160 orthologues and 2 paralogues. Ubiquitous expression in testis (RPKM 4.7), ovary (RPKM 3.2) and 25 other tissues.

功能概要

启用转录顺式调节区结合活性。在 RNA 聚合酶 II 的转录正调控上游或正调控内起作用。位于核内。 [由基因组资源联盟提供，2022 年 4 月]

Enables transcription cis-regulatory region binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

GABPB2 基因产物(9)

mRNA Protein Name
NM_001323906.2 NP_001310835.1 GA-binding protein subunit beta-2 isoform b
NM_001323907.2 NP_001310836.1 GA-binding protein subunit beta-2 isoform c
NM_001323908.2 NP_001310837.1 GA-binding protein subunit beta-2 isoform a
NM_001323909.2 NP_001310838.1 GA-binding protein subunit beta-2 isoform d
NM_001323910.2 NP_001310839.1 GA-binding protein subunit beta-2 isoform h
NM_001323911.2 NP_001310840.1 GA-binding protein subunit beta-2 isoform e
NM_001323912.2 NP_001310841.1 GA-binding protein subunit beta-2 isoform f
NM_001323913.2 NP_001310842.1 GA-binding protein subunit beta-2 isoform g
NM_144618.3 NP_653219.1 GA-binding protein subunit beta-2 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
9857059 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
9857059 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
9857059 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

GABPB2 蛋白结构

Ank_3

Ank_3: Ankyrin repeat (38 - 62)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (67 - 132)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 448 a.a.
蛋白主名 其他名称

GA-binding protein subunit beta-2

GA binding protein transcription factor beta subunit 2

GABPB2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra GABPB2 Q8TAK5 VAC14 Homo sapiens Q08AM6
Y2H Array
32296183
Intra GABPB2 Q8TAK5 VAC14 Homo sapiens Q08AM6
Y2H Prey Pooling
32296183
Intra GABPB2 Q8TAK5 LONRF1 Homo sapiens Q17RB8
Y2H Array
32296183
Intra GABPB2 Q8TAK5 LONRF1 Homo sapiens Q17RB8
Y2H Prey Pooling
32296183
Intra GABPB2 Q8TAK5 GABPA Homo sapiens Q06546
Anti Tag CoIP
33961781
Intra GABPB2 Q8TAK5 GABPA Homo sapiens Q06546
Y2H Prey Pooling
32296183
Intra GABPB2 Q8TAK5 GABPA Homo sapiens Q06546
Anti Tag CoIP
28514442
Intra GABPB2 Q8TAK5 GABPA Homo sapiens Q06546
Y2H Array
32296183
Intra GABPB2 Q8TAK5 GORASP2 Homo sapiens Q9H8Y8
Y2H Prey Pooling
25416956
Intra GABPB2 Q8TAK5 GORASP2 Homo sapiens Q9H8Y8
Validated Y2H
25416956
Intra GABPB2 Q8TAK5 GORASP2 Homo sapiens Q9H8Y8
Validated Y2H
32296183
Intra GABPB2 Q8TAK5 FLNA Homo sapiens P21333-2
Y2H Array
32814053
Intra GABPB2 Q8TAK5 FLNA Homo sapiens P21333-2
Validated Y2H
32814053
Intra GABPB2 Q8TAK5 FLNA Homo sapiens P21333-2
Y2H Pooling
32814053
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Paranoid Schizophrenia

Chronic Paranoid Schizophrenia

Paranoid Type Schizophrenia

Paranoid Type Schizophrenia Subchronic State

Paraphrenia - Late

Paraphrenic Schizophrenia

Schizophrenia, Paranoid
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05208 GABPB2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus GABPB2 VGNC VGNC:29190
Rattus norvegicus GABPB2 RGD RGD:1565234
Macaca mulatta GABPB2 VGNC VGNC:72798
Felis catus GABPB2 VGNC VGNC:80214
Mus musculus GABPB2 MGD MGI:95612
Canis familiaris GABPB2 VGNC VGNC:41052
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