GPSM3 - G protein signaling modulator 3 Gene

中文名称：G 蛋白信号调节因子 3

种属: Homo sapiens

同用名: G18; NG1; AGS4; G18.2; C6orf9; G18.1a; G18.1b

基因 ID: 63940 | 基因类型: protein coding

关于 GPSM3

Cytogenetic location: 6p21.32 Genomic coordinates (GRCh38): 6:32,190,766-32,195,523 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 162 orthologues and 6 paralogues. Broad expression in spleen (RPKM 56.7), lymph node (RPKM 55.9) and 21 other tissues.

功能概要

预测启用 GTPase 调节器活动。预计参与炎症反应的正向调节。预计在参与炎症反应和白细胞趋化性正调节的细胞因子产生的上游或正调节内起作用。预测位于细胞质和质膜。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable GTPase regulator activity. Predicted to be involved in positive regulation of inflammatory response. Predicted to act upstream of or within positive regulation of cytokine production involved in inflammatory response and positive regulation of leukocyte chemotaxis. Predicted to be located in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

GPSM3 基因产物(2)

mRNA	Protein	Name
NM_001276501.2	NP_001263430.1	G-protein-signaling modulator 3
NM_022107.3	NP_071390.1	G-protein-signaling modulator 3

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	25416956	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

GPSM3 蛋白结构

GoLoco

0
100
160 a.a.

蛋白主名

其他名称

G-protein-signaling modulator 3

G-protein signaling modulator 3 (AGS3-like, C. elegans)

GPSM3 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	GPSM3	Q9Y4H4	P4HA3	Homo sapiens	Q7Z4N8	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	P4HA3	Homo sapiens	Q7Z4N8	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	KRTAP13-3	Homo sapiens	Q3SY46	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	KRTAP13-3	Homo sapiens	Q3SY46	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	KRTAP11-1	Homo sapiens	Q8IUC1	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	KRTAP11-1	Homo sapiens	Q8IUC1	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	GTF3C3	Homo sapiens	Q9Y5Q9	Y2H Pooling	32814053
种属内	GPSM3	Q9Y4H4	GTF3C3	Homo sapiens	Q9Y5Q9	Validated Y2H	32814053
种属内	GPSM3	Q9Y4H4	GTF3C3	Homo sapiens	Q9Y5Q9	Y2H Array	32814053
种属内	GPSM3	Q9Y4H4	KIF1B	Homo sapiens	O60333-2	Y2H Pooling	32814053
种属内	GPSM3	Q9Y4H4	KIF1B	Homo sapiens	O60333-2	Validated Y2H	32814053
种属内	GPSM3	Q9Y4H4	KIF1B	Homo sapiens	O60333-2	Y2H Array	32814053
种属内	GPSM3	Q9Y4H4	STXBP5L	Homo sapiens	Q9Y2K9	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	STXBP5L	Homo sapiens	Q9Y2K9	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	TEX11	Homo sapiens	Q8IYF3-3	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	TEX11	Homo sapiens	Q8IYF3-3	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	CTAG1A	Homo sapiens	P78358	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	CTAG1A	Homo sapiens	P78358	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	SPAG8	Homo sapiens	Q99932-2	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	SPAG8	Homo sapiens	Q99932-2	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	HELT	Homo sapiens	A0A087WSW0	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	HELT	Homo sapiens	A0A087WSW0	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	UFSP1	Homo sapiens	Q6NVU6	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	UFSP1	Homo sapiens	Q6NVU6	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	SPRY3	Homo sapiens	O43610	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	SPRY3	Homo sapiens	O43610	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	MBD3L1	Homo sapiens	Q8WWY6	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	MBD3L1	Homo sapiens	Q8WWY6	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	CHRDL2	Homo sapiens	Q6WN34-2	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	CHRDL2	Homo sapiens	Q6WN34-2	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	ASB15	Homo sapiens	Q8WXK1	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	ASB15	Homo sapiens	Q8WXK1	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	ACMSD	Homo sapiens	Q8TDX5-2	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	ACMSD	Homo sapiens	Q8TDX5-2	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	KCNJ5-AS1	Homo sapiens	Q8TAV5	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	KCNJ5-AS1	Homo sapiens	Q8TAV5	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	RSPO4	Homo sapiens	Q2I0M5	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	RSPO4	Homo sapiens	Q2I0M5	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	SPMIP5	Homo sapiens	Q8WW14-2	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	SPMIP5	Homo sapiens	Q8WW14-2	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	FAM86C1P	Homo sapiens	Q9NVL1-2	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	FAM86C1P	Homo sapiens	Q9NVL1-2	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	RIPK4	Homo sapiens	P57078-2	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	RIPK4	Homo sapiens	P57078-2	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	HIGD2B	Homo sapiens	Q4VC39	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	HIGD2B	Homo sapiens	Q4VC39	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	PRR5	Homo sapiens	P85299-2	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	PRR5	Homo sapiens	P85299-2	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	KRTAP19-4	Homo sapiens	Q3LI73	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	KRTAP19-4	Homo sapiens	Q3LI73	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	ANKRD33	Homo sapiens	Q7Z3H0-1	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	ANKRD33	Homo sapiens	Q7Z3H0-1	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	C9orf57	Homo sapiens	Q5W0N0-2	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	C9orf57	Homo sapiens	Q5W0N0-2	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	IVD	Homo sapiens	P26440	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	IVD	Homo sapiens	P26440	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	YWHAZ	Homo sapiens	P63104	Anti Tag CoIP	33961781
种属内	GPSM3	Q9Y4H4	YWHAZ	Homo sapiens	P63104	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	YWHAZ	Homo sapiens	P63104	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	HSPB1	Homo sapiens	P04792	Validated Y2H	32814053
种属内	GPSM3	Q9Y4H4	HSPB1	Homo sapiens	P04792	Y2H Pooling	32814053
种属内	GPSM3	Q9Y4H4	HSPB1	Homo sapiens	P04792	Y2H Array	32814053
种属内	GPSM3	Q9Y4H4	GNAI2	Homo sapiens	P04899	Y2H Array	25416956
种属内	GPSM3	Q9Y4H4	GNAI3	Homo sapiens	P08754	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	GNAI3	Homo sapiens	P08754	Y2H Prey Pooling	25416956
种属内	GPSM3	Q9Y4H4	GNAI3	Homo sapiens	P08754	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	IQCE	Homo sapiens	Q6IPM2	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	IQCE	Homo sapiens	Q6IPM2	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	NR0B2	Homo sapiens	Q15466	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	NR0B2	Homo sapiens	Q15466	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	BMF	Homo sapiens	Q96LC9	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	BMF	Homo sapiens	Q96LC9	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	RNF11	Homo sapiens	Q9Y3C5	Validated Y2H	32814053
种属内	GPSM3	Q9Y4H4	RNF11	Homo sapiens	Q9Y3C5	Y2H Pooling	32814053
种属内	GPSM3	Q9Y4H4	RNF11	Homo sapiens	Q9Y3C5	Y2H Array	32814053
种属内	GPSM3	Q9Y4H4	GNAI1	Homo sapiens	P63096	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	GNAI1	Homo sapiens	P63096	Y2H Prey Pooling	25416956
种属内	GPSM3	Q9Y4H4	GNAI1	Homo sapiens	P63096	Validated Y2H	25416956
种属内	GPSM3	Q9Y4H4	GNAI1	Homo sapiens	P63096	Anti Tag CoIP	33961781
种属内	GPSM3	Q9Y4H4	GNAI1	Homo sapiens	P63096	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	GNAI1	Homo sapiens	P63096	Y2H Array	25416956
种属内	GPSM3	Q9Y4H4	COA7	Homo sapiens	Q96BR5	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	COA7	Homo sapiens	Q96BR5	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	HSF2BP	Homo sapiens	O75031	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	HSF2BP	Homo sapiens	O75031	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	ZNF20	Homo sapiens	P17024	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	ZNF20	Homo sapiens	P17024	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	WFS1	Homo sapiens	O76024	Y2H Array	32814053
种属内	GPSM3	Q9Y4H4	WFS1	Homo sapiens	O76024	Y2H Pooling	32814053
种属内	GPSM3	Q9Y4H4	WFS1	Homo sapiens	O76024	Validated Y2H	32814053
种属内	GPSM3	Q9Y4H4	USHBP1	Homo sapiens	Q8N6Y0	Y2H Array	25416956
种属内	GPSM3	Q9Y4H4	USHBP1	Homo sapiens	Q8N6Y0	Y2H Prey Pooling	25416956
种属内	GPSM3	Q9Y4H4	USHBP1	Homo sapiens	Q8N6Y0	Validated Y2H	25416956
种属内	GPSM3	Q9Y4H4	TADA2A	Homo sapiens	O75478	Y2H Array	25416956
种属内	GPSM3	Q9Y4H4	BATF2	Homo sapiens	Q8N1L9	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	BATF2	Homo sapiens	Q8N1L9	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	ZNF581	Homo sapiens	Q9P0T4	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	ZNF581	Homo sapiens	Q9P0T4	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	MEOX2	Homo sapiens	P50222	Y2H Array	25416956
种属内	GPSM3	Q9Y4H4	GATAD2B	Homo sapiens	Q8WXI9	Y2H Array	32296183
种属内	GPSM3	Q9Y4H4	GATAD2B	Homo sapiens	Q8WXI9	Y2H Prey Pooling	32296183
种属内	GPSM3	Q9Y4H4	FLNA	Homo sapiens	P21333-2	Y2H Pooling	32814053
种属内	GPSM3	Q9Y4H4	FLNA	Homo sapiens	P21333-2	Validated Y2H	32814053
种属内	GPSM3	Q9Y4H4	FLNA	Homo sapiens	P21333-2	Y2H Array	32814053

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Prostate Leiomyosarcoma

Leiomyosarcoma Of The Prostate

Hypermobility Of Coccyx

Coccygeal Hypermobility Syndrome

Hypermobility Of The Coccyx

Klippel-Feil Syndrome 3

Prostate Sarcoma

Sarcoma Of The Prostate

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS05761	GPSM3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	GPSM3	RGD	RGD:1303014
Felis catus	GPSM3	VGNC	VGNC:62699
Canis familiaris	GPSM3	VGNC	VGNC:41459
Macaca mulatta	GPSM3	VGNC	VGNC:72938
Mus musculus	GPSM3	MGD	MGI:2146785

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
沪ICP备15051369号-4 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2025 MedChemExpress. All Rights Reserved.

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4