GNAI1 - G protein subunit alpha i1 Gene

中文名称：G 蛋白亚基αi1

种属: Homo sapiens

同用名: Gi; HG1B; NEDHISB

关于 GNAI1

功能概要

鸟嘌呤核苷酸结合蛋白是由 α、β 和 γ 亚基组成的异源三聚体信号转导分子。 α 亚基结合鸟嘌呤核苷酸，可水解 GTP，并可与其他蛋白质相互作用。该基因编码的蛋白质代表抑制复合物的α亚基。编码的蛋白质是通过抑制腺苷酸环化酶响应 β-肾上腺素能信号的复合物的一部分。已发现该基因的两个转录本变体编码不同的亚型。[RefSeq 提供，2012 年 1 月]

Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with Other proteins. The protein encoded by this gene represents the alpha subunit of an inhibitory complex. The encoded protein is part of a complex that responds to beta-adrenergic signals by inhibiting Adenylate Cyclase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]