2. Gene
  3. PCP2 - Purkinje cell protein 2 Gene

PCP2 - Purkinje cell protein 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：浦肯野细胞蛋白 2

种属: Homo sapiens

同用名: PCD5; GPSM4

基因 ID: 126006 | 基因类型: protein coding

关于 PCP2

Cytogenetic location: 19p13.2 Genomic coordinates (GRCh38): 19:7,631,615-7,637,006 (from NCBI)

This gene has 2 transcripts (splice variants) and 105 orthologues. Biased expression in testis (RPKM 11.4), salivary gland (RPKM 2.1) and 8 other tissues.

功能概要

预测可启用胍基核苷酸交换因子活性。预计参与催化活性的调节。预测作用于视紫红质介导的信号通路的上游或内部。预测位于神经细胞体。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of catalytic activity. Predicted to act upstream of or within rhodopsin mediated signaling pathway. Predicted to be located in neuronal cell body. [provided by Alliance of Genome Resources, Apr 2022]

PCP2 基因产物(2)

mRNA Protein Name
NM_001271830.2 NP_001258759.1 Purkinje cell protein 2 homolog isoform 2
NM_174895.3 NP_777555.1 Purkinje cell protein 2 homolog isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
28514442 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PCP2 蛋白结构

GoLoco

GoLoco: GoLoco motif (23 - 45)

GoLoco

GoLoco: GoLoco motif (64 - 84)

  • 0
  • 100
  • 136 a.a.
蛋白主名 其他名称

Purkinje cell protein 2 homolog

CTD-3214H19.6

PCP2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra PCP2 Q8IVA1 MEOX1 Homo sapiens P50221
Y2H Array
32296183
Intra PCP2 Q8IVA1 MEOX1 Homo sapiens P50221
Y2H Prey Pooling
32296183
Intra PCP2 Q8IVA1 GNAI2 Homo sapiens P04899
Y2H Array
32296183
Intra PCP2 Q8IVA1 GNAI2 Homo sapiens P04899
Y2H Prey Pooling
32296183
Intra PCP2 Q8IVA1 GNAI3 Homo sapiens P08754
Y2H Prey Pooling
32296183
Intra PCP2 Q8IVA1 GNAI3 Homo sapiens P08754
Anti Tag CoIP
28514442
Intra PCP2 Q8IVA1 GNAI3 Homo sapiens P08754
Y2H Array
32296183
Intra PCP2 Q8IVA1 GNAI1 Homo sapiens P63096
Y2H Array
32296183
Intra PCP2 Q8IVA1 GNAI1 Homo sapiens P63096
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Atrial Tachyarrhythmia With Short Pr Interval

Lown-Ganong-Levine Syndrome

Syndrome Of Short P-R Interval, Normal Qrs Complexes, And Supraventricular Tachycardias

Lgl Syndrome
Gaucher Disease, Type Iiic

Gaucher Disease-Ophthalmoplegia-Cardiovascular Calcification Syndrome

Gaucher-Like Disease

GD3C

Gaucher'S Disease Type Iiic

Cardiovascular Gaucher Disease

Gaucher Disease Type 3c

Gaucher Disease 3c

Pseudo-Gaucher Disease
Gaucher Disease, Type Iii

Gaucher Disease, Subacute Neuronopathic Type

Gd Iii

Gaucher Disease, Chronic Neuronopathic Type

Gaucher Disease, Juvenile And Adult, Cerebral

Gaucher Disease Type 3

GD3

Gaucher'S Disease Type Iii

Gaucher Disease Type Iii

Gd 3

Cerebral Juvenile And Adult Form Of Gaucher Disease

Chronic Neuronopathic Gaucher Disease

Gaucher Disease 3

Cerebral, Juvenile And Adult, Gaucher Disease

Gaucher Disease Chronic Neuronopathic Type

Gaucher Disease Type Ii

Subacute Neuronopathic Gaucher Disease

Type 3 Gaucher Disease

Gaucher Disease, Type 3

Gaucher Disease, Type 2
Spinocerebellar Ataxia 1

Spinocerebellar Ataxia Type 1

SCA1

Olivopontocerebellar Atrophy I

Opca1

Opca4

Menzel Type Opca

Schut-Haymaker Type Opca

Spinocerebellar Atrophy I

Opca I

Olivopontocerebellar Atrophy Iv

Opca Iv

Cerebelloparenchymal Disorder I

Cpd1

Olivopontocerebellar Atrophy 1

Cerebelloparenchymal Disorder 1

Olivopontocerebellar Atrophy 4

Spinocerebellar Atrophy 1

Type 1 Spinocerebellar Ataxia

Spinocerebellar Ataxia-1

Ataxia, Spinocerebellar, Type 1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10167 PCP2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus PCP2 RGD RGD:1306217
Bos taurus PCP2 VGNC VGNC:32644
Canis familiaris PCP2 VGNC VGNC:44318
Mus musculus PCP2 MGD MGI:97508
Felis catus PCP2 VGNC VGNC:64072
Macaca mulatta PCP2 VGNC VGNC:75706
Others PCP2 NCBI
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