ARHGEF4 - Rho guanine nucleotide exchange factor 4 Gene

中文名称：Rho 鸟嘌呤核苷酸交换因子 4

种属: Homo sapiens

同用名: ASEF; GEF4; STM6; ASEF1; SMIM39

关于 ARHGEF4

功能概要

Rho GTP 酶在许多细胞过程中起着重要作用，这些过程由通过 G 蛋白偶联受体起作用的细胞外刺激物启动。该基因编码的蛋白质可能与 G 蛋白形成复合物并刺激 Rho 依赖性信号。已发现编码不同亚型的多个可变剪接转录本变体，但尚未确定某些变体的全长性质。[RefSeq 提供，2013 年 6 月]

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The protein encoded by this gene may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jun 2013]