1. Gene
  2. CDYL2 - chromodomain Y like 2 Gene

CDYL2 - chromodomain Y like 2 Gene

中文名称:染色体 Y 样 2

种属: Homo sapiens

同用名: PCCP1

基因 ID: 124359 | 基因类型: protein coding

关于 CDYL2

Cytogenetic location: 16q23.2 Genomic coordinates (GRCh38): 16:80,597,907-80,805,037 (from NCBI)

This gene has 7 transcripts (splice variants), 198 orthologues and 13 paralogues. Broad expression in testis (RPKM 6.1), placenta (RPKM 3.9) and 20 other tissues.

功能概要

预测启用转录辅阻遏物活性。预测参与转录的负调控,DNA 模板化。预计活跃于核心。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

CDYL2 基因产物(1)

mRNA Protein Name
NM_152342.4 NP_689555.2 chromodomain Y-like protein 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17577209 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CDYL2 蛋白结构

Chromo

Chromo: Chromo (CHRromatin Organisation MOdifier) domain (7 - 56)

ECH_1

ECH_1: Enoyl-CoA hydratase/isomerase (255 - 489)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 506 a.a.
蛋白主名 其他名称

chromodomain Y-like protein 2

CDY-like 2

CDYL2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra CDYL2 Q8N8U2 LMO3 Homo sapiens Q8TAP4-4
Validated Y2H
32296183
Intra CDYL2 Q8N8U2 PRMT5 Homo sapiens O14744
Anti Tag CoIP
23455924
Intra CDYL2 Q8N8U2 PRMT5 Homo sapiens O14744
Y2H
23455924
Intra CDYL2 Q8N8U2 ZBTB9 Homo sapiens Q96C00
Validated Y2H
32296183
Intra CDYL2 Q8N8U2 NXF1 Homo sapiens Q9UBU9
Validated Y2H
32296183
Intra CDYL2 Q8N8U2 DVL3 Homo sapiens Q92997
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus CDYL2 RGD RGD:1309548
Mus musculus CDYL2 MGD MGI:1923046
Macaca mulatta CDYL2 VGNC VGNC:71076
Canis familiaris CDYL2 VGNC VGNC:53315
Felis catus CDYL2 VGNC VGNC:60724
Bos taurus CDYL2 VGNC VGNC:27160