RBM17 - RNA binding motif protein 17 Gene

中文名称：RNA 结合基序蛋白 17

种属: Homo sapiens

同用名: SPF45

基因 ID: 84991 | 基因类型: protein coding

关于 RBM17

Cytogenetic location: 10p15.1 Genomic coordinates (GRCh38): 10:6,089,034-6,117,447 (from NCBI)

This gene has 12 transcripts (splice variants) and 225 orthologues. Ubiquitous expression in bone marrow (RPKM 17.7), lymph node (RPKM 15.8) and 25 other tissues.

功能概要

该基因编码一种 RNA 结合蛋白。编码的蛋白质是剪接体复合物的一部分，在 mRNA 剪接的第二个催化步骤中发挥作用。已经描述了选择性剪接的转录物变体。相关假基因存在于 9 号和 15 号染色体上。[RefSeq 提供，2009 年 3 月]

This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 9 and 15. [provided by RefSeq, Mar 2009]

RBM17 基因产物(2)

mRNA	Protein	Name
NM_001145547.2	NP_001139019.1	splicing factor 45
NM_032905.5	NP_116294.1	splicing factor 45

基因本体论

分子功能
生物过程

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	16189514	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in alternative mRNA splicing, via spliceosome	IMP IMP: 通过突变表型推断	17589525	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RBM17 蛋白结构

G-patch

RRM_5

0
100
200
300
401 a.a.

蛋白主名

其他名称

splicing factor 45

45 kDa-splicing factor

RBM17 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	RBM17	Q96I25	FAM9B	Homo sapiens	Q8IZU0	Y2H Array	25416956
Intra	RBM17	Q96I25	FAM9B	Homo sapiens	Q8IZU0	Validated Y2H	25416956
Intra	RBM17	Q96I25	CCHCR1	Homo sapiens	Q8TD31-3	Y2H Prey Pooling	32296183
Intra	RBM17	Q96I25	CCHCR1	Homo sapiens	Q8TD31-3	Y2H Array	32296183
Intra	RBM17	Q96I25	PPP1R12C	Homo sapiens	Q9BZL4-5	Y2H Prey Pooling	25416956
Intra	RBM17	Q96I25	PPP1R12C	Homo sapiens	Q9BZL4-5	Y2H Array	25416956
Intra	RBM17	Q96I25	NEK7	Homo sapiens	Q8TDX7	Validated Y2H	32814053
Intra	RBM17	Q96I25	NEK7	Homo sapiens	Q8TDX7	Y2H Pooling	32814053
Intra	RBM17	Q96I25	NEK7	Homo sapiens	Q8TDX7	Y2H Array	32814053
Intra	RBM17	Q96I25	SF1	Homo sapiens	Q15637-4	Y2H Array	32296183
Intra	RBM17	Q96I25	SF1	Homo sapiens	Q15637-4	Y2H Prey Pooling	32296183
Intra	RBM17	Q96I25	DHX15	Homo sapiens	O43143	Anti Tag CoIP	35271311
Intra	RBM17	Q96I25	DHX15	Homo sapiens	O43143	Validated Y2H	25416956
Intra	RBM17	Q96I25	DHX15	Homo sapiens	O43143	Y2H Array	25416956
Intra	RBM17	Q96I25	SF3B1	Homo sapiens	O75533-1	X-Ray Diffraction	17589525
Intra	RBM17	Q96I25	SF3B1	Homo sapiens	O75533-1	Pull Down	17589525
Intra	RBM17	Q96I25	SF3A2	Homo sapiens	Q15428	Affinity Chrom	17332742
Intra	RBM17	Q96I25	SF3A2	Homo sapiens	Q15428	Anti Tag CoIP	33961781
Intra	RBM17	Q96I25	SF3A2	Homo sapiens	Q15428	Anti Tag CoIP	28514442
Intra	RBM17	Q96I25	SUGP1	Homo sapiens	Q8IWZ8	Anti Tag CoIP	35271311
Intra	RBM17	Q96I25	QRICH1	Homo sapiens	Q2TAL8	Validated Y2H	25416956
Intra	RBM17	Q96I25	QRICH1	Homo sapiens	Q2TAL8	Y2H Prey Pooling	25416956
Intra	RBM17	Q96I25	CCDC170	Homo sapiens	Q8IYT3	Y2H Array	32296183
Intra	RBM17	Q96I25	CCDC170	Homo sapiens	Q8IYT3	Y2H Prey Pooling	32296183
Intra	RBM17	Q96I25	U2SURP	Homo sapiens	O15042	Anti Tag CoIP	33961781
Intra	RBM17	Q96I25	U2SURP	Homo sapiens	O15042	Anti Tag CoIP	35271311
Intra	RBM17	Q96I25	U2SURP	Homo sapiens	O15042	Y2H	22365833
Intra	RBM17	Q96I25	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	25416956
Intra	RBM17	Q96I25	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	32296183
Intra	RBM17	Q96I25	GOLGA2	Homo sapiens	Q08379	Y2H Array	32296183
Intra	RBM17	Q96I25	SAT1	Homo sapiens	P21673	Y2H	21516116
Intra	RBM17	Q96I25	SAT1	Homo sapiens	P21673	Validated Y2H	25416956
Intra	RBM17	Q96I25	HSF2BP	Homo sapiens	O75031	Y2H Array	32296183
Intra	RBM17	Q96I25	HSF2BP	Homo sapiens	O75031	Y2H Prey Pooling	32296183
Intra	RBM17	Q96I25	PECAM1	Homo sapiens	P16284	Y2H Pooling	32814053
Intra	RBM17	Q96I25	PECAM1	Homo sapiens	P16284	Validated Y2H	32814053
Intra	RBM17	Q96I25	PECAM1	Homo sapiens	P16284	Y2H Array	32814053
Intra	RBM17	Q96I25	WFS1	Homo sapiens	O76024	Validated Y2H	32814053
Intra	RBM17	Q96I25	WFS1	Homo sapiens	O76024	Y2H Array	32814053
Intra	RBM17	Q96I25	WFS1	Homo sapiens	O76024	Y2H Pooling	32814053
Intra	RBM17	Q96I25	PPP1R12C	Homo sapiens	Q9BZL4	Y2H Prey Pooling	32296183
Intra	RBM17	Q96I25	PPP1R12C	Homo sapiens	Q9BZL4	Validated Y2H	32296183
Intra	RBM17	Q96I25	PPP1R12C	Homo sapiens	Q9BZL4	Y2H Array	32296183
Intra	RBM17	Q96I25	U2AF2	Homo sapiens	P26368	Pull Down	17589525
Intra	RBM17	Q96I25	SF1	Homo sapiens	Q15637	Y2H Fragment Pooling	26420826
Intra	RBM17	Q96I25	SF1	Homo sapiens	Q15637	Pull Down	17589525
Intra	RBM17	Q96I25	IQCN	Homo sapiens	Q9H0B3	Y2H Prey Pooling	25416956
Intra	RBM17	Q96I25	IQCN	Homo sapiens	Q9H0B3	Y2H Array	25416956
Intra	RBM17	Q96I25	CEP55	Homo sapiens	Q53EZ4	Y2H Array	32296183
Intra	RBM17	Q96I25	CEP55	Homo sapiens	Q53EZ4	Y2H Array	31515488
Intra	RBM17	Q96I25	CEP55	Homo sapiens	Q53EZ4	Y2H Prey Pooling	32296183
Intra	RBM17	Q96I25	SF3B1	Homo sapiens	O75533	Anti Tag CoIP	33961781
Intra	RBM17	Q96I25	SF3B1	Homo sapiens	O75533	Anti Tag CoIP	28514442
Intra	RBM17	Q96I25	SF3B1	Homo sapiens	O75533	Anti Tag CoIP	35271311
Intra	RBM17	Q96I25	SF3B1	Homo sapiens	O75533	Phage Display	37219487
Intra	RBM17	Q96I25	SF3B1	Homo sapiens	O75533	Anti Tag CoIP	22365833
Intra	RBM17	Q96I25	SF3B1	Homo sapiens	O75533	Y2H	22365833
Intra	RBM17	Q96I25	ATXN1	Homo sapiens	P54253	Anti Tag CoIP	18337722
Intra	RBM17	Q96I25	ATXN1	Homo sapiens	P54253	Y2H	18337722

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Sickle Cell Anemia

Hemoglobin Sc Disease	Anemia, Sickle Cell
Hbsc Disease	Sickle Cell-Hemoglobin C Disease Syndrome
Hb Ss Disease	Sickle Cell Trait
Drepanocytosis	Haemoglobin Sc Disease
Hb Sc Disease	Hb-S/Hb-C Disease
Hb-Ss Disease Without Crisis	Hemoglobin S Disease Without Crisis
Sickle Cell Anaemia	Sickle-Cell/Hb-C Disease Without Crisis
Sickle Cell - Hemoglobin C Disease	Hbs Disease
Hemoglobin S Disease	Sickling Disorder Due To Hemoglobin S
SKCA	Sickle Cell Disease
Sickle Cell-Hemoglobin C Disease	Sickle-Cell Disease Carrier
Sickle-Cell Heterozygous Disorder	Haemoglobin A-S Genotype
Hb-S - [Sickle Cell Haemoglobin] Carrier	Sickle Cell Haemoglobin Trait
As - [Sickle Cell Trait]	Hbas - [Sickle Cell Haemoglobin Trait]
Sickle-Cell Trait Haemoglobin Disease	Haemoglobin Sickle Cell Trait Disorder
Heterozygous Sickle Cell Trait	Hbas - [Heterozygous Haemoglobin S]

Spinocerebellar Ataxia 1

Spinocerebellar Ataxia Type 1	SCA1
Olivopontocerebellar Atrophy I	Opca1
Opca4	Menzel Type Opca
Schut-Haymaker Type Opca	Spinocerebellar Atrophy I
Opca I	Olivopontocerebellar Atrophy Iv
Opca Iv	Cerebelloparenchymal Disorder I
Cpd1	Olivopontocerebellar Atrophy 1
Cerebelloparenchymal Disorder 1	Olivopontocerebellar Atrophy 4
Spinocerebellar Atrophy 1	Type 1 Spinocerebellar Ataxia
Spinocerebellar Ataxia-1	Ataxia, Spinocerebellar, Type 1

Autosomal Dominant Cerebellar Ataxia

Spinocerebellar Ataxia	Adca
Pierre Marie Cerebellar Ataxia	Ataxia, Spinocerebellar
Sca	Autosomal Dominant Spinocerebellar Ataxia
Spinocerebellar Ataxias

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS11737	RBM17 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Canis familiaris	RBM17	VGNC	VGNC:45411
Mus musculus	RBM17	MGD	MGI:1924188
Bos taurus	RBM17	VGNC	VGNC:33788
Macaca mulatta	RBM17	VGNC	VGNC:76496
Rattus norvegicus	RBM17	RGD	RGD:1311208
Felis catus	RBM17	VGNC	VGNC:64522

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

RBM17 - RNA binding motif protein 17 Gene

关于 RBM17

功能概要

RBM17 基因产物(2)

RBM17 蛋白结构

RBM17 蛋白互作信息

关联疾病

直系同源

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RBM17 - RNA binding motif protein 17 Gene

关于 RBM17

功能概要

RBM17 基因产物(2)

RBM17 蛋白结构

RBM17 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z