1. Gene
  2. BAX - BCL2 associated X, apoptosis regulator Gene

BAX - BCL2 associated X, apoptosis regulator Gene

中文名称:BCL2 相关 X,细胞凋亡调节因子

种属: Homo sapiens

同用名: BCL2L4

基因 ID: 581 | 基因类型: protein coding

关于 BAX

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:48,954,875-48,961,798 (from NCBI)

This gene has 12 transcripts (splice variants), 206 orthologues, 8 paralogues and is associated with 51 phenotypes. Ubiquitous expression in colon (RPKM 24.0), spleen (RPKM 21.8) and 25 other tissues.

功能概要

该基因编码的蛋白质属于 BCL2 蛋白家族。 BCL2 家族成员形成异二聚体或同二聚体,并作为参与多种细胞活动的抗或促凋亡调节剂。该蛋白与 BCL2 形成异二聚体,并起凋亡激活剂的作用。 Bax 与 BCL2 的关联和比率也决定了细胞在凋亡刺激后的存活或死亡。据报道,该蛋白质与线粒体电压依赖性阴离子通道 (VDAC) 相互作用并增加其开放,从而导致膜电位损失和细胞色素 c 的释放。该基因的表达受肿瘤抑制因子 P53 的调节,并已被证明参与 P53 介导的细胞凋亡。已经报道了该基因的多个选择性剪接的转录物变体,其编码不同的亚型。[RefSeq 提供,2019 年 12 月]

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. The association and the ratio of Bax to BCL2 also determines survival or death of a cell following an apoptotic stimulus. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated Apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Dec 2019]

BAX 基因产物(11)

mRNA Protein Name
NM_138762.2
NM_138761.4 NP_620116.1 apoptosis regulator BAX isoform alpha
NR_027882.2
NM_001291428.2 NP_001278357.1 apoptosis regulator BAX isoform 1
NM_001291431.2 NP_001278360.1 apoptosis regulator BAX isoform zeta
NM_001291429.2 NP_001278358.1 apoptosis regulator BAX isoform gamma
NM_004324.4 NP_004315.1 apoptosis regulator BAX isoform beta
NM_138763.4 NP_620118.1 apoptosis regulator BAX isoform delta
NM_001291430.2 NP_001278359.1 apoptosis regulator BAX isoform lambda
XM_047439168.1 XP_047295124.1 apoptosis regulator BAX isoform X1
NM_138764.5 NP_620119.2 apoptosis regulator BAX isoform sigma
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables BH3 domain binding IDA
IDA: 通过直接分析推断
21199865 GOA
enables BH3 domain binding IPI
IPI: 通过物理相互作用推断
15705586 GOA
enables channel activity IDA
IDA: 通过直接分析推断
9219694 GOA
enables identical protein binding IPI
IPI: 通过物理相互作用推断
10620504 GOA
enables lipid binding IDA
IDA: 通过直接分析推断
14522999 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
9027312 GOA
enables protein heterodimerization activity IPI
IPI: 通过物理相互作用推断
9111042 GOA
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
16608847 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in B cell apoptotic process IDA
IDA: 通过直接分析推断
15214043 GOA
involved in B cell receptor apoptotic signaling pathway IDA
IDA: 通过直接分析推断
15214043 GOA
involved in apoptotic mitochondrial changes IDA
IDA: 通过直接分析推断
9843949 GOA
involved in apoptotic process IDA
IDA: 通过直接分析推断
9660918 GOA
involved in apoptotic process IMP
IMP: 通过突变表型推断
9531611 GOA
involved in apoptotic signaling pathway IDA
IDA: 通过直接分析推断
16424160 GOA
involved in cellular response to virus IDA
IDA: 通过直接分析推断
25609812 GOA
involved in establishment or maintenance of transmembrane electrochemical gradient IDA
IDA: 通过直接分析推断
9843949 GOA
involved in execution phase of apoptosis IMP
IMP: 通过突变表型推断
11350920 GOA
involved in extrinsic apoptotic signaling pathway IDA
IDA: 通过直接分析推断
15214043 GOA
involved in intrinsic apoptotic signaling pathway IDA
IDA: 通过直接分析推断
9219694 GOA
involved in intrinsic apoptotic signaling pathway in response to DNA damage IDA
IDA: 通过直接分析推断
11912183 GOA
involved in mitochondrial fragmentation involved in apoptotic process IDA
IDA: 通过直接分析推断
12499352 GOA
involved in mitochondrial fusion IDA
IDA: 通过直接分析推断
14769861 GOA
involved in negative regulation of mitochondrial membrane potential IDA
IDA: 通过直接分析推断
16751333 GOA
involved in negative regulation of protein binding IDA
IDA: 通过直接分析推断
9388232 GOA
involved in positive regulation of apoptotic DNA fragmentation IMP
IMP: 通过突变表型推断
11350920 GOA
involved in positive regulation of apoptotic process IDA
IDA: 通过直接分析推断
16751333 GOA
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
17289999 GOA
involved in positive regulation of intrinsic apoptotic signaling pathway IMP
IMP: 通过突变表型推断
14963330 GOA
involved in positive regulation of neuron apoptotic process IDA
IDA: 通过直接分析推断
15637643 GOA
involved in positive regulation of protein-containing complex assembly IDA
IDA: 通过直接分析推断
9111042 GOA
involved in positive regulation of release of cytochrome c from mitochondria IDA
IDA: 通过直接分析推断
14963330 GOA
involved in positive regulation of release of cytochrome c from mitochondria IMP
IMP: 通过突变表型推断
21262771 GOA
involved in regulation of apoptotic process IDA
IDA: 通过直接分析推断
25609812 GOA
involved in regulation of mitochondrial membrane potential IDA
IDA: 通过直接分析推断
9843949 GOA
involved in release of cytochrome c from mitochondria IDA
IDA: 通过直接分析推断
9843949 GOA
involved in release of matrix enzymes from mitochondria IDA
IDA: 通过直接分析推断
9843949 GOA
involved in response to toxic substance IDA
IDA: 通过直接分析推断
16307838 GOA
involved in supramolecular fiber organization IDA
IDA: 通过直接分析推断
31690630 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of BAK complex IDA
IDA: 通过直接分析推断
16113678 GOA
part of BAX complex IDA
IDA: 通过直接分析推断
14522999 GOA
part of Bcl-2 family protein complex IDA
IDA: 通过直接分析推断
21199865 GOA
colocalizes with cell periphery IDA
IDA: 通过直接分析推断
21803450 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
16302269 GOA
located in cytosol IDA
IDA: 通过直接分析推断
11912183 GOA
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
16424160 GOA
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
16424160 GOA
located in mitochondrial outer membrane IDA
IDA: 通过直接分析推断
29531808 GOA
part of mitochondrial permeability transition pore complex IDA
IDA: 通过直接分析推断
9843949 GOA
located in mitochondrion IDA
IDA: 通过直接分析推断
11912183 GOA
located in nuclear envelope IDA
IDA: 通过直接分析推断
12925958 GOA
located in nucleus IDA
IDA: 通过直接分析推断
12925958 GOA
located in nucleus IMP
IMP: 通过突变表型推断
15102863 GOA
part of pore complex IDA
IDA: 通过直接分析推断
9219694 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

BAX 蛋白结构

Bcl-2

Bcl-2: Apoptosis regulator proteins, Bcl-2 family (63 - 158)

  • 0
  • 100
  • 192 a.a.
蛋白主名 其他名称

apoptosis regulator BAX

BCL2 associated X protein

BCL2-associated X protein omega

Baxdelta2G9

Baxdelta2G9omega

Baxdelta2omega

bcl-2-like protein 4

bcl2-L-4

BAX 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra BAX Q07812 MCL1 Homo sapiens Q07820
Anti Bait CoIP
17525735
Intra BAX Q07812 MCL1 Homo sapiens Q07820
Anti Tag CoIP
18981409
Intra BAX Q07812 MCL1 Homo sapiens Q07820
Anti Tag CoIP
21199865
Cross BAX Q07812 TOM22 Saccharomyces cerevisiae P49334
Anti Bait CoIP
22198199
Cross BAX Q07812 TOM40 Saccharomyces cerevisiae P23644
Anti Bait CoIP
22198199
Cross BAX Q07812 TOM70 Saccharomyces cerevisiae P07213
Anti Bait CoIP
22198199
Cross BAX Q07812 P70444-PRO_0000223236 Mus musculus P70444-PRO_0000223236
FRET
19062087
Intra BAX Q07812 RNF144B Homo sapiens Q7Z419
Anti Bait CoIP
20300062
Intra BAX Q07812 RNF144B Homo sapiens Q7Z419
BN-PAGE
20300062
Intra BAX Q07812 BCL2L1 Homo sapiens Q07817-1
Anti Tag CoIP
17289999
Intra BAX Q07812 BCL2L1 Homo sapiens Q07817-1
Anti Bait CoIP
15131699
Intra BAX Q07812 BCL2L1 Homo sapiens Q07817-1
X-Ray Diffraction
21199865
Intra BAX Q07812 BCL2L1 Homo sapiens Q07817-1
FPS
19074440
Intra BAX Q07812 BCL2L1 Homo sapiens Q07817-1
Fluorescence
21458670
Intra BAX Q07812 BCL2L1 Homo sapiens Q07817-1
Anti Bait CoIP
21671007
Intra BAX Q07812 BCL2L1 Homo sapiens Q07817-1
Anti Tag CoIP
18981409
Intra BAX Q07812 BCL2L1 Homo sapiens Q07817-1
Anti Tag CoIP
21199865
Intra BAX Q07812 UVRAG Homo sapiens Q9P2Y5
Anti Bait CoIP
21597469
Intra BAX Q07812 UVRAG Homo sapiens Q9P2Y5
Pull Down
21597469
Intra BAX Q07812 XRCC6 Homo sapiens P12956
Anti Bait CoIP
15205477
Intra BAX Q07812 BCL2L12 Homo sapiens Q9HB09
Y2H
29749471
Intra BAX Q07812 BAX Homo sapiens Q07812
GMS
19062087
Intra BAX Q07812 BAX Homo sapiens Q07812
Anti Tag CoIP
17289999
Intra BAX Q07812 BAX Homo sapiens Q07812
Crosslink
23374347
Intra BAX Q07812 BAX Homo sapiens Q07812
Crosslink
17668322
Intra BAX Q07812 BAX Homo sapiens Q07812
BN-PAGE
22198199
Intra BAX Q07812 BAX Homo sapiens Q07812
Crosslink
19767770
Intra BAX Q07812 BAX Homo sapiens Q07812
Crosslink
18835031
Intra BAX Q07812 BAX Homo sapiens Q07812
Crosslink
19074440
Intra BAX Q07812 BAX Homo sapiens Q07812
GMS
10620504
Intra BAX Q07812 BAX Homo sapiens Q07812
BN-PAGE
23374347
Intra BAX Q07812 BAX Homo sapiens Q07812
Crosslink
18547146
Intra BAX Q07812 BAX Homo sapiens Q07812
Crosslink
20850011
Intra BAX Q07812 BAX Homo sapiens Q07812
Polymerization
20850011
Intra BAX Q07812 BAX Homo sapiens Q07812
Anti Bait CoIP
19767770
Intra BAX Q07812 BAX Homo sapiens Q07812
Comigration in SDS
14963330
Intra BAX Q07812 BAX Homo sapiens Q07812
Experimental Interac
1558161
Intra BAX Q07812 BAX Homo sapiens Q07812
FRET
19062087
Intra BAX Q07812 BAX Homo sapiens Q07812
X-Ray Diffraction
23374347
Intra BAX Q07812 BAX Homo sapiens Q07812
GMS
20360684
Intra BAX Q07812 BID Homo sapiens P55957
PLA
25241761
Intra BAX Q07812 BID Homo sapiens P55957
SPR
17289999
Intra BAX Q07812 BID Homo sapiens P55957
Anti Bait CoIP
20956295
Intra BAX Q07812 BAK1 Homo sapiens Q16611
Anti Tag CoIP
17289999
Intra BAX Q07812 BAK1 Homo sapiens Q16611
Anti Tag CoIP
15901672
Intra BAX Q07812 BAK1 Homo sapiens Q16611
CoIP
16439990
Intra BAX Q07812 BCL2L11 Homo sapiens O43521
Anti Bait CoIP
17525735
Intra BAX Q07812 BCL2L11 Homo sapiens O43521
FRET
19427863
Intra BAX Q07812 BCL2L11 Homo sapiens O43521
SPR
17289999
Intra BAX Q07812 BCL2L11 Homo sapiens O43521
Anti Bait CoIP
19427863
Intra BAX Q07812 SH3GLB1 Homo sapiens Q9Y371-1
Anti Bait CoIP
19074440
Intra BAX Q07812 BCL2L2 Homo sapiens Q92843
Anti Tag CoIP
17289999
Intra BAX Q07812 BCL2L2 Homo sapiens Q92843
Anti Tag CoIP
18981409
Cross BAX Q07812 OPG035 vaccinia virus P17361
Anti Tag CoIP
17485524
Cross BAX Q07812 OPG035 vaccinia virus P17361
Anti Bait CoIP
17485524
Intra BAX Q07812 HSF2BP Homo sapiens O75031
Y2H Prey Pooling
32296183
Intra BAX Q07812 HSF2BP Homo sapiens O75031
Y2H Array
32296183
Intra BAX Q07812 PYCARD Homo sapiens Q9ULZ3
Anti Bait CoIP
14730312
Intra BAX Q07812 PYCARD Homo sapiens Q9ULZ3
Pull Down
14730312
Intra BAX Q07812 PYCARD Homo sapiens Q9ULZ3
Confocal
14730312
Intra BAX Q07812 PYCARD Homo sapiens Q9ULZ3
Anti Tag CoIP
14730312
Intra BAX Q07812 BCL2 Homo sapiens P10415
Anti Tag CoIP
21199865
Intra BAX Q07812 BCL2 Homo sapiens P10415
Anti Tag CoIP
17289999
Intra BAX Q07812 BCL2 Homo sapiens P10415
Anti Bait CoIP
17525735
Intra BAX Q07812 BCL2 Homo sapiens P10415
IF
26004684
Intra BAX Q07812 BCL2 Homo sapiens P10415
Anti Tag CoIP
18981409
Intra BAX Q07812 KCNA3 Homo sapiens P22001
Anti Bait CoIP
18818304
Intra BAX Q07812 MT-RNR2 Homo sapiens Q8IVG9
FPS
12732850
Intra BAX Q07812 MT-RNR2 Homo sapiens Q8IVG9
Y2H
12732850
Intra BAX Q07812 SNCA Homo sapiens P37840
PLA
25241761
Cross BAX Q07812 UL37 Human cytomegalovirus P16778
Fluorescence Spectr
23213219
Cross BAX Q07812 UL37 Human cytomegalovirus P16778
NMR
23213219
Cross BAX Q07812 tom40 Neurospora crassa P24391
Anti Bait CoIP
17635912
Cross BAX Q07812 P26662-PRO_0000037647 Hepatitis C virus P26662-PRO_0000037647
Anti Bait CoIP
12925958
Cross BAX Q07812 P26662-PRO_0000037647 Hepatitis C virus P26662-PRO_0000037647
Pull Down
12925958
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Colon Adenocarcinoma

Adenocarcinoma Of Colon

Adenocarcinoma Of The Colon

Colonic Adenocarcinoma

Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour

Ataxia-Telangiectasia

Ataxia Telangiectasia

Louis-Bar Syndrome

AT

At1

Ataxia-Telangiectasia Syndrome

Ataxia - Telangiectasia Variant

Boder-Sedgwick Syndrome

Louis Bar Syndrome

Cerebello-Oculocutaneous Telangiectasia

Immunodeficiency With Ataxia Telangiectasia

A-T

Ataxia Telangiectasia Syndrome

Atm

Telangiectasia, Cerebello-Oculocutaneous

Ataxia-Telangiectasia Variant

Neuroblastoma

Nb

Neuroblastoma, Susceptibility To

Neuroblastomas

Central Neuroblastoma

Parkinson Disease, Late-Onset

Parkinson Disease

Parkinson'S Disease

PD

PARK

Parkinson Disease, Susceptibility To

Late Onset Parkinson'S Disease

Late Onset Parkinson Disease

Paralysis Agitans

Primary Parkinsonism

Idiopathic Parkinson Disease

Parkinson'S

Parkinson Disease, Late-Onset, Susceptibility To

Parkinson Disease, Age Of Onset, Modifier

Lewy Body Parkinson Disease

Idiopathic Parkinson'S Disease

Pd - [Parkinson Disease]

Parkinson Disease Nos

Parkinson, Nos

Primary Parkinson Disease

Gastric Cancer

Stomach Cancer

Stomach Carcinoma

Gastric Carcinoma

Gastric Cancer, Somatic

Gastric Neoplasm

Carcinoma Of Stomach

Stomach Neoplasms

Malignant Neoplasm Of Stomach

Gastric Cancer Risk After H. Pylori Infection

Cancer Of The Stomach

Adult Stomach Cancer

Adult Stomach Carcinoma

GASC

Gastric Cancer Intestinal

Gastric Cancers

Gastric Carcinomas

Cancer, Gastric

Stomach Neoplasm

Malignant Neoplasm Of Body Of Stomach

Malignant Tumor Of Lesser Curve Of Stomach

Gastrocarcinoma Of Unspecified Site

Leather Bottle Stomach

Carcinoma Of Fundus Of Stomach

Cancer Of Fundus Of Stomach

Primary Malignant Neoplasm Of Body Of Stomach

Cancer Of Body Of Stomach

Primary Malignant Neoplasm Of Pyloric Antrum

Pyloric Antrum Cancer

Malignant Tumour Of Stomach

Torticollis

Contracture Of Neck

Wry Neck

Wry Neck/Torticollis

Follicular Lymphoma

Lymphoma, Follicular

Lymphoma Follicular

Brill-Symmers' Disease

Large Cell Follicular Non-Hodgkin Lymphoma

Diffuse Follicle Centre Lymphoma

Diffuse Follicular Lymphoma Nos

Follicular Nodular Non-Hodgkin Lymphoma, Unspecified

Follicular Large Cell Cleaved Or Noncleaved Lymphoma

Large Cell Follicular Noncleaved Lymphoma

Follicular Lymphoma With Or Without Diffuse Areas

Histiocytic Follicular Lymphoma

Histiocytic Nodular Lymphoma

Histiocytic Nodular Malignant Lymphoma

Large Cell Follicular Lymphoma

Large Cell Noncleaved Follicular Lymphoma

Large Cell Noncleaved Follicular Malignant Lymphoma

Nodular Reticulum Cell Sarcoma

Noncleaved Follicular Lymphoma

T-Cell Acute Lymphoblastic Leukemia

T-Cell Leukemia

Acute T Cell Leukemia

Precursor T Lymphoblastic Leukemia

Precursor T-Lymphoblastic Lymphoma/Leukemia

T Acute Lymphoblastic Leukemia

T-Cell Acute Lymphocytic Leukaemia

T-Cell Lymphoblastic Leukemia/Lymphoma

Leukemia T-Cell

Leukemia, T-Cell

Leukemia, Acute, Lymphoblastic, T-Cell

Leukemia, T-Cell Acute Lymphoblastic

Leukemia, Acute T-Cell

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Precursor T-Cell Lymphoblastic Lymphoma

Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma

Brain Cancer

Malignant Neoplasm Of Brain

Adult Brain Tumor

Brain Neoplasms

Brain Neoplasm

Neoplasm Of Brain

Primary Malignant Neoplasm Of Brain

Brain Tumors

Adult Malignant Brain Neoplasm

Brain Neoplasm, Adult

Bt - Brain Tumour

Malignant Brain Tumour

Malignant Primary Brain Neoplasm

Malignant Primary Brain Tumor

Malignant Tumor Of Adult Brain

Malignant Tumor Of Brain

Primary Brain Neoplasm

Primary Brain Tumor

Tumor Of The Brain

Brain Tumor, Adult

Brain Tumor Primary

Malignant Primary Brain Tumors

Primary Brain Tumors

Cancer, Brain

Brain Tumor, Primary

Osteogenic Sarcoma

Osteosarcoma

OSRC

Osteosarcoma, Somatic

Neoplasms, Bone Tissue

Bone Tissue Neoplasm

Osteoid Sarcoma

Skeletal Sarcoma

Osteosarcoma Of Bone

Bone Sarcoma

Cervical Adenoid Cystic Carcinoma

Adenoid Cystic Carcinoma Of The Cervix Uteri

Pancreatic Cancer

Pancreatic Carcinoma

Familial Pancreatic Carcinoma

Pancreatic Neoplasm

Carcinoma Of Pancreas

Pancreatic Carcinoma, Familial

Malignant Neoplasm Of Pancreas

Pancreatic Acinar Carcinoma

Pancreatic Tumor

Familial Pancreatic Cancer

Neoplasm Of The Pancreas

Pancreatic Carcinoma, Somatic

Pancreatic Cancer, Somatic

Ca Body Of Pancreas

Ca Head Of Pancreas

Ca Tail Of Pancreas

Malignant Neoplasm Of Body Of Pancreas

Malignant Neoplasm Of Head Of Pancreas

Malignant Neoplasm Of Tail Of Pancreas

Pancreas Neoplasm

Exocrine Cancer

Exocrine Pancreas Carcinoma

Hereditary Pancreatic Cancer

Hereditary Pancreatic Carcinoma

PNCA

Cancer Of The Pancreas

Pancreatic Cancer, Susceptibility To

Carcinoma Of Head Of Pancreas

Pancreatic Neoplasms

Pancreatic Tumors

Cancer, Pancreatic

Cancer Of Pancreas

Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site

B-Cell Lymphoma

Lymphoma, B-Cell

B-Cell Lymphomas

B-Cell Lymphocytic Neoplasm

Lymphoma B-Cell

B-Cell Lymphoma Nos

Lung Cancer Susceptibility 3

Lung Adenocarcinoma

Adenocarcinoma Of Lung

LNCR3

Adenocarcinoma Of Lung, Susceptibility To

Bronchogenic Lung Adenocarcinoma

Nonsmall Cell Adenocarcinoma

Adenocarcinoma Lung

Lung Adenocarcinomas

Non-Small Cell Adenocarcinoma

Denys-Drash Syndrome

Drash Syndrome

DDS

Nephropathy, Wilms Tumor, And Genital Anomalies

Wilms Tumor And Pseudohermaphroditism

Wilms Tumor And Pseudo- Or True Hermaphroditism

Nephropathy Associated With Male Pseudohermaphroditism And Wilms' Tumor

Pseudohermaphroditism, Nephron Disorder And Wilms' Tumor

Wilms Tumor-Dsd Syndrome

Wilms Tumor-Disorder Of Sex Development Syndrome

Liver Disease

Liver Failure

Liver Diseases

Abnormality Of The Liver

Liver Dysfunction

Disorder Of Liver

Hepatic Disorder

Hepatic Disease

Disease Of Bilirubin Metabolism

Disorder Of Bilirubin Metabolism

Liver Decompensation

Liver Function Failure

Hepatic Failure Nos

Liver Failure Nos

End Stage Liver Disease

Decompensated Liver Failure

Decompensation Of Liver Function

Hepatic Decompensation

Hepatic Insufficiency

Liver Cell Necrosis With Hepatic Failure

Liver Insufficiency

Decompensated Liver Disease

End Stage Liver Failure

Liver Necrosis With Hepatic Failure

Li-Fraumeni Syndrome

Sarcoma Family Syndrome Of Li And Fraumeni

Sbla Syndrome

LFS

Li-Fraumeni Familiar Cancer Susceptibility Syndrome

Sarcoma, Breast, Leukaemia And Adrenal Gland Syndrome

Lfs1

Li Fraumeni Syndrome

Sarcoma, Breast, Leukemia, And Adrenal Gland Syndrome

Lfl

Sbla Syndrome Li-Fraumeni-Like Syndrome

Li-Fraumeni Syndrome 1

Lymphoma

Lymphoid Cancer

Lymphomas

Lymphoid Cancers

Lymphoid Neoplasm

Lymphoma Nos

Nhl - [Non-Hodgkin Lymphoma]

Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma, Nos

Non-Hodgkin Malignant Lymphoma Nos

Lymphoma, Non-Hodgkin, Familial

Non-Hodgkin Lymphoma

Lymphoma, Non-Hodgkin

NHL

Lymphoma, Non-Hodgkin, Somatic

Lymphoma, Follicular, Somatic

Familial Non-Hodgkin Lymphoma

Lymphoma Non-Hodgkins

Follicular Lymphoma, Somatic

Lymphosarcoma

Non-Hodgkins Lymphoma

Myeloma, Multiple

Multiple Myeloma

Kahler Disease

Myelomatosis

Plasma Cell Myeloma

Medullary Plasmacytoma

Multiple Myeloma, Resistance To

Myeloma

Plasma Cell Dyscrasia

Multiple Myeloma, Susceptibility To

Myeloma - Multiple

Kahler'S Disease

Kahler-Bozzolo Disease

Plasma Cell Myelomas

MM

Plasma Cell Neoplasm

Primary Systemic Amyloidosis

Primary Amyloidosis

Immunoglobulin Deposition Disease

Plasmacytic Myeloma

Multiple Myelomata

Multiple Myeloma Nos

Multiple Myeloma Without Mention Of Remission

Monostotic Plasma Cell Myeloma

Mm - [Multiple Myeloma]

Glioblastoma

Glioblastoma Multiforme

Gbm

Adult Glioblastoma Multiforme

Grade Iv Adult Astrocytic Tumor

Primary Glioblastoma Multiforme

Spongioblastoma Multiforme

Adult Glioblastoma

Primary Glioblastoma

Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Protection Against

Lung Cancer, Susceptibility To

Adenocarcinoma Of Lung, Somatic

Nonsmall Cell Lung Cancer

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma

Breast Cancer

Breast Carcinoma

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Male Breast Cancer

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation

Panniculitis

Nodular Panniculitis

Scrapie
Endometrial Cancer

Endometrial Carcinoma

Endometrial Neoplasm

Malignant Neoplasm Of Endometrium

Endometrioid Carcinoma

Endometrial Neoplasms

Carcinoma, Endometrioid

Endometrial Cancer, Familial

Endometrial Carcinoma, Somatic

Endometrial Cancer, Susceptibility To

Endometrial Ca

Malignant Endometrial Neoplasm

Neoplasm Of Endometrium

Primary Malignant Neoplasm Of Endometrium

Tumor Of Endometrium

Carcinoma Of The Endometrium

Endometrioid Carcinoma Of Female Reproductive System

ENDMC

Carcinoma Endometrioid

Endometrial Cancers

Cancer, Endometrial

Uterine Corpus Cancer

Breast Adenocarcinoma

Mammary Adenocarcinoma

Adenocarcinoma Of Breast

Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon

Ovary Adenocarcinoma

Ovarian Adenocarcinoma

Adenocarcinoma Of The Ovary

Ovarian Adenoacanthoma

Adenocarcinoma Of Ovary

High Grade Glioma

Malignant Glioma

Glial Cell Tumor

Glioma, Malignant

Malignant Neuroglial Tumor

Neuroglial Tumor

Glioma

Malignant Gliomas

Fuchs' Endothelial Dystrophy

Fuchs Endothelial Corneal Dystrophy

Fuchs Endothelial Dystrophy

Fuchs Dystrophy

Fced

Fuchs' Corneal Dystrophy

Fuchs' Endothelial Corneal Dystrophy

Fuchs Atrophy

Fuchs Corneal Dystrophy

Endoepithelial Corneal Dystrophy

Fecd

Late Hereditary Endothelial Dystrophy

Corneal Dystrophy, Fuchs Endothelial

Dystrophy, Corneal, Fuchs Endothelial

Corneal Dystrophy, Fuchs' Endothelial, 1

Thrombocytopenia

Low Platelet Count

Low Platelets

Decreased Platelets

Platelet Dysfunction Nos

Glycogen Storage Disease

Glycogenosis

Glycogenoses

Gsd

Storage Disease, Glycogen

Gsd - [Glycogen Storage Disease]

Glycogen Thesaurismosis

Diffuse Glycogenosis

Generalised Glycogen Storage Disease

Generalised Glycogenosis

Generalised Glycogen Storage Disease Of Infants

Glycogen Synthase Deficiency

Absolute Glaucoma

Blind Hypertensive Eye

Glaucoma Absolute

Adenocarcinoma

Adenocarcinomas

Adenoacanthoma Of Unspecified Site

Adenocarcinoid Of Unspecified Site

Adenocarcinoid Tumour Of Unspecified Site

Adenocarcinoma And Carcinoid Combined Of Unspecified Site

Adenocarcinoma Nos

Melanoma

Malignant Melanoma

Cutaneous Melanoma

Naevocarcinoma

Malignant Melanomas

Oral Lichen Planus

Oral Lichenoid Lesions

Lichen Planus Oral

Lichen Planus, Oral

Laryngeal Squamous Cell Carcinoma

Epidermoid Carcinoma Of The Larynx

Squamous Cell Carcinoma Of Larynx

Squamous Cell Carcinoma Of The Larynx

Squamous Cell Carcinoma Of Head And Neck

Leukemia

Leukemias

Leukaemia, Unspecified, Without Mention Of Remission

Aleukemic Leukaemia

Chronic Leukaemia

Subacute Leukaemia

Leukaemia Disorder

Leukaemia Nos

Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer

Ischemia

Acute Coronary Syndrome

Bladder Cancer

Urinary Bladder Cancer

Bladder Carcinoma

Urinary Bladder Carcinoma

Bladder Neoplasm

Bladder Tumor

Cancer, Bladder

Malignant Neoplasm Of Urinary Bladder

Carcinoma Of Bladder

Bladder Cancer, Somatic

Tumor Of The Bladder

Carcinoma Of Urinary Bladder

Bladder Carcinoma Urinary

Cancer Of The Urinary Bladder

Cancer, Urinary Bladder

Malignant Bladder Neoplasm

Malignant Bladder Tumor

Neoplasm Of The Bladder

Neoplasm Of The Urinary Bladder

Tumor Of The Urinary Bladder

Urinary Bladder Neoplasm

BLC

Urothelial Carcinoma Of The Bladder

Bladder Tumors

Urinary Bladder Neoplasms

Bladder Cancer Nos

Vesical Cancer Nos

Malignant Neoplasm Of Bladder, Part Unspecified

Malignant Tumour Of Urinary Bladder

Primary Malignant Neoplasm Of Bladder

Leukemia, Chronic Lymphocytic

Chronic Lymphocytic Leukemia

B-Cell Chronic Lymphocytic Leukemia

CLL

B-Cell Chronic Lymphoid Leukemia

Chronic Lymphatic Leukemia

Chronic Lymphocytic Leukaemia

Lymphoplasmacytic Leukemia

Small Lymphocytic Lymphoma

Leukemia, Chronic Lymphatic

B-Cell Chronic Lymphocytic Leukaemia

Chronic Lymphatic Leukaemia

Lymphoplasmacytic Leukaemia

B Cell Chronic Lymphocytic Leukemia

Chronic B-Cell Lymphocytic Leukemia

Leukemia, Lymphocytic, Chronic

B-Cll

Chronic Lymphoid Leukemia

Leukemia Lymphocytic Chronic

Lymphoma Small Lymphocytic

Leukemia, Lymphocytic, Chronic, B-Cell

Nasopharyngeal Carcinoma

Malignant Neoplasm Of Nasopharynx

Npc

Nasopharyngeal Cancer

Nasopharyngeal Carcinoma 1

Nasopharynx Carcinoma

Nasopharyngeal Neoplasms

Npca

Carcinoma Of Nasopharynx

Malignant Nasopharyngeal Tumor

Nasopharynx Cancer

Squamous Cell Carcinoma Of The Nasopharynx

Nasopharyngeal Neoplasm

Cancer Of Nasopharynx

Ovarian Cancer

Ovarian Carcinoma

Ovarian Neoplasm

Malignant Tumour Of Ovary

Epithelial Ovarian Cancer

Neoplasm Of Ovary

Ovarian Neoplasms

Ovarian Cancers

Malignant Neoplasm Of Ovary

Primary Malignant Neoplasm Of Ovary

Ovarian Cancer, Somatic

Malignant Ovarian Tumor

Ovary Neoplasm

Primary Ovarian Cancer

Tumor Of The Ovary

Cancer Of The Ovary

Malignant Neoplasm Of The Ovary

Malignant Tumor Of The Ovary

Ovarian Malignant Tumor

OC

Ovarian Carcinomas

Cancer, Ovarian

Cancer Of Ovary

Ovary Cancer

Ca Ovary

Acute Promyelocytic Leukemia

Leukemia, Acute Promyelocytic

Acute Myeloblastic Leukemia Type 3

Aml M3

APL

Leukemia, Acute Promyelocytic, Somatic

Aml With T(15

17)(Q22

Q12)

(Pml/Raralpha) And Variants

Apml

Acute Myeloblastic Leukemia 3

Acute Myeloid Leukemia With T(15

17)(Q22

Q12)

(Pml/Raralpha) And Variants

Acute Myeloblastic Leukaemia Type 3

Acute Myeloid Leukaemia M3

Acute Myeloid Leukemia M3

Acute Promyelocytic Leukaemia

M3 Anll

Myeloid Leukemia, Acute, M3

Leukemia Promyelocytic Acute

Leukemia, Promyelocytic, Acute

Leukemia, Acute, Promyelocytic

Basal Cell Carcinoma

Basal Cell Cancer

Basal Cell Neoplasm

Basal Cell Carcinoma Of Skin

Malignant Basal Cell Tumor

Basal Cell Tumor

Epithelioma Basal Cell

Malignant Basal Cell Neoplasm

Rodent Ulcer

Carcinoma Basal Cell

Neoplasms, Basal Cell

Basal Cell Carcinomas

Experimental Organism Basal Cell Carcinoma

Nodulo-Ulcerative Basal Cell Carcinoma

Basalioma

Basal Cell Epithelioma Of Skin

Bcc - [Basal Cell Carcinoma] Of Skin

Rodent Ulcer Of Skin

Rodent Ulcer Of Unspecified Site

Basal Cell Epithelioma Of Unspecified Site

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta BAX VGNC VGNC:70230
Felis catus BAX VGNC VGNC:69139
Rattus norvegicus BAX RGD RGD:2192
Mus musculus BAX MGD MGI:99702
Canis familiaris BAX VGNC VGNC:38388
Bos taurus BAX VGNC VGNC:26428
Others BAX NCBI