CYB5R2 - cytochrome b5 reductase 2 Gene

中文名称：细胞色素 b5 还原酶 2

种属: Homo sapiens

同用名: B5R.2

关于 CYB5R2

功能概要

该基因编码的蛋白质属于黄素蛋白吡啶核苷酸细胞色素还原酶蛋白质家族。细胞色素 b 型 NAD (P) H 氧化还原酶涉及许多过程，包括胆固醇生物合成、脂肪酸去饱和和延长以及中性粒细胞和巨噬细胞的呼吸爆发。细胞色素 b5 还原酶具有可溶性和膜结合形式，是选择性剪接的产物。在动物细胞中，膜结合形式与内质网结合，在那里它是脂肪酸去饱和复合物的成员。可变剪接导致多个转录本变体。[RefSeq 提供，2014 年 11 月]

The protein encoded by this gene belongs to the flavoprotein pyridine nucleotide cytochrome reductase family of proteins. Cytochrome b-type NAD(P)H oxidoreductases are implicated in many processes including Cholesterol biosynthesis, fatty acid desaturation and elongation, and respiratory burst in neutrophils and macrophages. Cytochrome b5 reductases have soluble and membrane-bound forms that are the product of alternative splicing. In animal cells, the membrane-bound form binds to the endoplasmic reticulum, where it is a member of a fatty acid desaturation complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]