CAB39 - calcium binding protein 39 Gene

中文名称：钙结合蛋白 39

种属: Homo sapiens

同用名: MO25; CGI-66

基因 ID: 51719 | 基因类型: protein coding

关于 CAB39

Cytogenetic location: 2q37.1 Genomic coordinates (GRCh38): 2:230,712,842-230,821,075 (from NCBI)

This gene has 6 transcripts (splice variants), 139 orthologues and 1 paralogue. Ubiquitous expression in colon (RPKM 18.8), appendix (RPKM 18.4) and 25 other tissues.

功能概要

启用激酶结合活性和蛋白丝氨酸/苏氨酸激酶激活剂活性。参与细胞内信号转导；肽基丝氨酸磷酸化；和蛋白质磷酸化的正调节。位于细胞外外泌体。与肝细胞癌有关。肝细胞癌和胰腺癌的生物标志物。 [由基因组资源联盟提供，2022 年 4 月]

Enables kinase binding activity and protein serine/threonine kinase activator activity. Involved in intracellular signal transduction; peptidyl-serine phosphorylation; and positive regulation of protein phosphorylation. Located in extracellular exosome. Implicated in hepatocellular carcinoma. Biomarker of hepatocellular carcinoma and pancreatic Cancer. [provided by Alliance of Genome Resources, Apr 2022]

CAB39 基因产物(3)

mRNA	Protein	Name
NM_001130849.2	NP_001124321.1	calcium-binding protein 39
NM_001130850.2	NP_001124322.1	calcium-binding protein 39
NM_016289.4	NP_057373.1	calcium-binding protein 39

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables kinase binding	IPI IPI: 通过物理相互作用推断	19892943	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	14676191	GOA
enables protein kinase activator activity	IDA IDA: 通过直接分析推断	19892943	GOA
enables protein serine/threonine kinase activator activity	IDA IDA: 通过直接分析推断	19892943	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in intracellular signal transduction	IDA IDA: 通过直接分析推断	24393035	GOA
involved in peptidyl-serine phosphorylation	IDA IDA: 通过直接分析推断	24393035	GOA
involved in positive regulation of peptidyl-threonine phosphorylation	IDA IDA: 通过直接分析推断	24393035	GOA
involved in positive regulation of protein serine/threonine kinase activity	IDA IDA: 通过直接分析推断	19892943	GOA
involved in signal transduction	IDA IDA: 通过直接分析推断	24393035	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytoplasm	IDA IDA: 通过直接分析推断	14517248	GOA
part of serine/threonine protein kinase complex	IPI IPI: 通过物理相互作用推断	19892943	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CAB39 蛋白结构

Mo25

0
100
200
300
341 a.a.

蛋白主名

其他名称

calcium-binding protein 39

MO25alpha

CAB39 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	CAB39	Q9Y376	STK24	Homo sapiens	Q9Y6E0-2	Validated Y2H	32296183
种属内	CAB39	Q9Y376	STK24	Homo sapiens	Q9Y6E0-2	Y2H Array	32296183
种属内	CAB39	Q9Y376	STK24	Homo sapiens	Q9Y6E0-2	Y2H Prey Pooling	32296183
种属内	CAB39	Q9Y376	STRADA	Homo sapiens	Q7RTN6	Anti Tag CoIP	21423148
种属内	CAB39	Q9Y376	STRADA	Homo sapiens	Q7RTN6	Anti Tag CoIP	33961781
种属内	CAB39	Q9Y376	MCCD1	Homo sapiens	P59942	Y2H Array	32296183
种属内	CAB39	Q9Y376	MCCD1	Homo sapiens	P59942	Y2H Prey Pooling	32296183
种属内	CAB39	Q9Y376	STRADA	Homo sapiens	Q7RTN6-1	Anti Bait CoIP	26479318
种属内	CAB39	Q9Y376	STK26	Homo sapiens	Q9P289-1	Comigration in SDS	23434407
种属内	CAB39	Q9Y376	STK26	Homo sapiens	Q9P289-1	Anti Tag CoIP	23434407
种属内	CAB39	Q9Y376	STK26	Homo sapiens	Q9P289-1	BLI	23434407
种属内	CAB39	Q9Y376	STK26	Homo sapiens	Q9P289-1	X-Ray Diffraction	23434407
种属内	CAB39	Q9Y376	STK26	Homo sapiens	Q9P289-1	GMS	23434407
种属内	CAB39	Q9Y376	STK39	Homo sapiens	Q9UEW8	Anti Tag CoIP	21423148
种属内	CAB39	Q9Y376	STK39	Homo sapiens	Q9UEW8	SPR	21423148
种属内	CAB39	Q9Y376	STK11	Homo sapiens	Q15831	Anti Tag CoIP	33961781
种属内	CAB39	Q9Y376	STK11	Homo sapiens	Q15831	Affinity Chrom	15733851
种属内	CAB39	Q9Y376	STK11	Homo sapiens	Q15831	Anti Bait CoIP	26479318
种属内	CAB39	Q9Y376	STK11	Homo sapiens	Q15831	Anti Tag CoIP	14676191
种属内	CAB39	Q9Y376	STK11	Homo sapiens	Q15831	PLA	25241761
种属内	CAB39	Q9Y376	STRADB	Homo sapiens	Q9C0K7	Y2H Fragment Pooling	23414517
种属内	CAB39	Q9Y376	STRADB	Homo sapiens	Q9C0K7	Anti Tag CoIP	14676191
种属内	CAB39	Q9Y376	MED7	Homo sapiens	O43513	Y2H Array	32296183
种属内	CAB39	Q9Y376	MED7	Homo sapiens	O43513	Y2H Prey Pooling	32296183
种属内	CAB39	Q9Y376	STK26	Homo sapiens	Q9P289	Anti Tag CoIP	21423148
种属内	CAB39	Q9Y376	STK26	Homo sapiens	Q9P289	SPR	21423148
种属内	CAB39	Q9Y376	GOLGA2	Homo sapiens	Q08379	Y2H Array	32296183
种属内	CAB39	Q9Y376	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	32296183
种属内	CAB39	Q9Y376	OXSR1	Homo sapiens	O95747	SPR	21423148
种属内	CAB39	Q9Y376	CEP44	Homo sapiens	Q9C0F1	Y2H Prey Pooling	32296183
种属内	CAB39	Q9Y376	CEP44	Homo sapiens	Q9C0F1	Y2H Array	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

CAB39 抗体

目录号	产品名	应用	反应物种
HY-P83016	CAB39 Antibody (YA2761)	WB, IHC-P, IP	Human, Mouse, Rat

关联疾病

疾病名称

别名

Hepatocellular Carcinoma

Liver Cancer	Primary Liver Cancer
HCC	Hepatoma
Malignant Neoplasm Of Liver	Liver Neoplasms
Cancer, Hepatocellular	Liver Cell Carcinoma
Lcc	Hepatoblastoma, Somatic
Hepatic Cancer	Primary Malignant Neoplasm Of Liver
Rare Tumor Of Liver And Intrahepatic Biliary Tract	Hepatocellular Carcinoma, Somatic
Hepatocellular Carcinoma, Childhood Type, Somatic	Hepatocellular Cancer, Somatic
Ca Liver - Primary	Hepatic Neoplasm
Malignant Hepato-Biliary Neoplasm	Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary
Malignant Neoplasm Of Liver, Primary	Malignant Tumor Of Liver
Neoplasm Of Liver	Non-Resectable Primary Hepatic Malignant Neoplasm
Resectable Malignant Neoplasm Of Liver	Resectable Malignant Neoplasm Of The Liver
Primary Liver Carcinoma	Primary Malignant Liver Neoplasm
Primary Cancer Of Liver	Primary Tumor Of The Liver
Rare Tumor Of Liver And Ibt	Hepatocellular Cancer
Neoplasm Of The Liver	Carcinoma, Hepatocellular
Hepatomas	Liver Neoplasm
Liver Carcinoma	Liver And Intrahepatic Biliary Tract Carcinoma
Malignant Hepatobiliary Neoplasm	Adult Primary Hepatocellular Carcinoma
Hepatoblastoma	Carcinoma Of Liver
Malignant Liver Tumour	Malignant Hepatic Tumour

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS01778	CAB39 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否
HY-RS01779	CAB39L Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	CAB39	VGNC	VGNC:60281
Canis familiaris	CAB39	VGNC	VGNC:38619
Mus musculus	CAB39	MGD	MGI:107438
Bos taurus	CAB39	VGNC	VGNC:26661
Rattus norvegicus	CAB39	RGD	RGD:1306390
Macaca mulatta	CAB39	VGNC	VGNC:70590
Others	CAB39	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

CAB39 - calcium binding protein 39 Gene

关于 CAB39

功能概要

CAB39 基因产物(3)

CAB39 蛋白结构

CAB39 蛋白互作信息

CAB39 抗体

关联疾病

直系同源

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CAB39 - calcium binding protein 39 Gene

关于 CAB39

功能概要

CAB39 基因产物(3)

CAB39 蛋白结构

CAB39 蛋白互作信息

CAB39 抗体

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z