1. Gene
  2. ZNF280C - zinc finger protein 280C Gene

ZNF280C - zinc finger protein 280C Gene

中文名称:锌指蛋白 280C

种属: Homo sapiens

同用名: ZPET; SUHW3; ZNF633

基因 ID: 55609 | 基因类型: protein coding

关于 ZNF280C

This gene has 2 transcripts (splice variants), 87 orthologues and 28 paralogues. Broad expression in testis (RPKM 6.8), endometrium (RPKM 1.7) and 21 other tissues.

功能概要

该基因编码含锌指结构域的蛋白质家族成员。该家族成员包含多个 Cys2-His2 (C2H2) 型锌指结构域,这是最常见的锌指结构域类型,可自行折叠形成结合锌离子的 β-β-α 结构。[RefSeq 提供,2011 年 8 月]

This gene encodes a member of the zinc finger domain-containing protein family. This family member contains multiple Cys2-His2(C2H2)-type zinc finger domains, the most common type of zinc finger domain that self-folds to form a beta-beta-alpha structure that binds a zinc ion. [provided by RefSeq, Aug 2011]

ZNF280C 基因产物(1)

mRNA Protein Name
NM_017666.5 NP_060136.1 zinc finger protein 280C
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
27705803 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

ZNF280C 蛋白结构

DUF4195

DUF4195: Domain of unknown function (DUF4195) (46 - 227)

  • 0
  • 200
  • 400
  • 600
  • 737 a.a.
蛋白主名 其他名称

zinc finger protein 280C

suppressor of hairy wing homolog 3

ZNF280C 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra ZNF280C Q8ND82 KRTAP10-6 Homo sapiens P60371
Y2H Prey Pooling
32296183
Intra ZNF280C Q8ND82 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra ZNF280C Q8ND82 CBX1 Homo sapiens P83916
Y2H Array
32296183
Intra ZNF280C Q8ND82 CBX1 Homo sapiens P83916
Y2H Prey Pooling
32296183
Intra ZNF280C Q8ND82 CBX3 Homo sapiens Q13185
Y2H Prey Pooling
32296183
Intra ZNF280C Q8ND82 CBX3 Homo sapiens Q13185
Y2H Array
32296183
Intra ZNF280C Q8ND82 CBX3 Homo sapiens Q13185
Anti Tag CoIP
33961781
Intra ZNF280C Q8ND82 CBX5 Homo sapiens P45973
Y2H Array
32296183
Intra ZNF280C Q8ND82 CBX5 Homo sapiens P45973
Y2H Prey Pooling
32296183
Intra ZNF280C Q8ND82 TSPYL2 Homo sapiens Q9H2G4
Validated Y2H
32296183
Intra ZNF280C Q8ND82 TSPYL2 Homo sapiens Q9H2G4
Y2H Array
32296183
Intra ZNF280C Q8ND82 TSPYL2 Homo sapiens Q9H2G4
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Exudative Vitreoretinopathy 1

Retinopathy Of Prematurity

Retrolental Fibroplasia

EVR1

Criswick-Schepens Syndrome

Rop

Exudative Vitreoretinopathy, Familial, Autosomal Dominant

Fevr, Autosomal Dominant

Premature Retinopathy

Vitreoretinopathy, Exudative 1

Autosomal Dominant Familial Exudative Vitreoretinopathy

Fevr

Vitreoretinopathy, Exudative, Type 1

Retinopathy Of Prematurity Nos

Rlf- [Retrolental Fibroplasia]

Rop - [Retinopathy Of Prematurity]

Terry Syndrome

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus ZNF280C VGNC VGNC:37238
Mus musculus ZNF280C MGD MGI:2387585
Canis familiaris ZNF280C VGNC VGNC:48688
Felis catus ZNF280C VGNC VGNC:67285
Rattus norvegicus ZNF280C RGD RGD:1564669
Macaca mulatta ZNF280C VGNC VGNC:79560