E2F6 - E2F transcription factor 6 Gene

中文名称：E2F 转录因子 6

种属: Homo sapiens

同用名: E2F-6

关于 E2F6

功能概要

该基因编码转录因子家族的一个成员，该家族在细胞周期的控制中起着至关重要的作用。由该基因编码的蛋白质缺乏在其他家族成员中发现的反式激活和肿瘤抑制蛋白关联结构域，并包含一个在抑制转录中起作用的模块化抑制结构域。它在复合物中与染色质修饰因子相互作用。该基因在 22 号染色体和 X 号染色体上存在假基因。可变剪接导致多个转录本变体。[RefSeq 提供，2013 年 5 月]

This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains found in Other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene on chromosomes 22 and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]