Glia maturation factor beta/GMFB 蛋白, Human

Glia maturation factor beta/GMFB Protein, Human is a major component of glia maturation factor family, essential in brain development and responses to stress.

人类胶质细胞成熟因子β (GMFB) 是GMF 家族的主要组成部分，在啮齿动物中枢神经系统中高度表达。GMFB 对于大脑发育和压力反应至关重要。在分子水平上，GMFB 可以调节细胞骨架重塑，发挥生长因子或促炎介质的作用，从而在许多不同的细胞过程中发挥关键作用^[1]。

Human

E. coli

Tag Free

P60983 (M1-H142)

2764  [NCBI]

MSESLVVCDVAEDLVEKLRKFRFRKETNNAAIIMKIDKDKRLVVLDEELEGISPDELKDELPERQPRFIVYSYKYQHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNKLVQTAELTKVFEIRNTEDLTEEWLREKLGFFH

Approximately 19.3 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS or 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.

• [1]. Yin G, et al. Glia maturation factor beta is required for reactive gliosis after traumatic brain injury in zebrafish. Exp Neurol. 2018 Jul;305:129-138.  [Content Brief]