Glial fibrillary acidic 蛋白, Human (432a.a, His)

Glial fibrillary acidic protein (GFAP) belongs to the class III intermediate filament family and serves as a cell-specific marker that is critical for distinguishing astrocytes from other glial cells during the development of the central nervous system. GFAP plays a key role in differentiating the identity of astrocytes, contributing to their unique characteristics. Glial fibrillary acidic Protein, Human (432a.a, His) is the recombinant human-derived Glial fibrillary acidic protein, expressed by E. coli , with N-6*His labeled tag. The total length of Glial fibrillary acidic Protein, Human (432a.a, His) is 432 a.a., with molecular weight of 54.0 kDa.

胶质纤维酸性蛋白 (GFAP) 被归类为 III 类中间丝，作为细胞特异性标记物，对于区分星形胶质细胞与其他胶质细胞至关重要，特别是在中枢神经系统的发育阶段。作为星形胶质细胞的关键结构成分，GFAP 有助于细胞骨架的形成和维持，提供结构支撑和稳定性。此外，GFAP 被认为是识别和表征各种生理和病理环境中星形胶质细胞的可靠标记。据报道，它与 SYNM 相互作用，表明 GFAP 与星形胶质细胞内参与细胞骨架动力学或细胞信号传导的其他蛋白质之间存在潜在的功能联系。正在进行的研究可能会为 GFAP 在星形胶质细胞生物学和中枢神经系统发育中的多方面作用提供进一步的见解。

Human

E. coli

N-6*His

P14136 (M1-M432)

2670

54.0 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.22 μm filtered solution of 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add 5-50% of glycerol (final concentration). Our default final concentration of glycerol is 50%. Customers could use it as reference.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.