1. 重组蛋白
  2. Viral Proteins
  3. RSV Proteins
  4. RSV G proteins
  5. glycoprotein/G 蛋白, HRSV (HEK293, His)

glycoprotein/G 蛋白, HRSV (HEK293, His)

目录号: HY-P74124
产品使用指南

糖蛋白/G蛋白通过硫酸乙酰肝素相互作用将病毒颗粒附着到宿主细胞膜上,从而启动感染,从而在感染中发挥关键作用。它还与宿主 CX3CR1(CX3C 趋化因子 fractalkine 的受体)相互作用,有助于免疫调节和促进感染。glycoprotein/G 蛋白, HRSV (HEK293, His) 是重组的 糖蛋白/G 蛋白,由 HEK293 表达,带有 C-His 标签。

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描述

Glycoproteins/G proteins play a key role in infection by attaching viral particles to the host cell membrane through heparan sulfate interactions, thereby initiating infection. It also interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, contributing to immune regulation and promoting infection. glycoprotein/G Protein, HRSV (HEK293, His) is the recombinant Virus-derived glycoprotein/G protein, expressed by HEK293 , with C-His labeled tag.

研究背景

糖蛋白/G蛋白通过与硫酸乙酰肝素相互作用将病毒颗粒附着到宿主细胞膜上,从而启动感染,从而在感染中发挥关键作用。此外,它与宿主 CX3CR1(CX3C 趋化因子 fractalkine 的受体)相互作用,有助于免疫调节并促进感染。与其他副粘病毒附着蛋白不同,该糖蛋白缺乏神经氨酸酶和血凝活性。其独特的功能使病毒能够通过充当抗原诱饵并调节携带 Fc-gamma 受体的白细胞的活性来逃避抗体依赖性复制限制。

种属

Virus

表达系统

HEK293

标签

C-His

蛋白编号

O36633-1 (H67-A299)

基因 ID

1489824  [NCBI]

蛋白结构
N-term
HRSV G (H67-A299)
Accession # O36633-1
His
C-term
同用名
Major surface glycoprotein G; mG; Mature sG; G
分子量

80-90 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

glycoprotein/G Protein, HRSV (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
glycoprotein/G Protein, HRSV (HEK293, His)
目录号:
HY-P74124
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