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  3. Grancalcin/GCA 蛋白, Human (GST)

Grancalcin/GCA 蛋白, Human (GST)

目录号: HY-P72635
COA 产品使用指南

Grancalcin/GCA 蛋白是一种钙结合蛋白,在中性粒细胞粘附纤连蛋白和粘着斑形成中发挥潜在作用。作为同二聚体,该蛋白表现出与 SRI 和 LCP1 的相互作用,表明其参与与细胞粘附和细胞骨架动力学相关的分子途径。Grancalcin/GCA 蛋白, Human (GST) 是重组的 Grancalcin/GCA 蛋白,由 E. coli 表达,带有 N-GST 标签。

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规格 价格 是否有货 数量
10 μg ¥1300 In-stock
50 μg ¥3600 In-stock
100 μg   询价  

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描述

Grancalcin/GCA protein is a calcium-binding protein that plays a potential role in neutrophil adhesion to fibronectin and focal adhesion formation.As a homodimer, this protein exhibits interactions with SRI and LCP1, suggesting its involvement in molecular pathways related to cell adhesion and cytoskeletal dynamics.Grancalcin/GCA Protein, Human (GST) is the recombinant human-derived Grancalcin/GCA protein, expressed by E.coli , with N-GST labeled tag.

研究背景

Grancalcin (GCA) 是一种钙结合蛋白,在中性粒细胞粘附纤连蛋白和粘着斑形成中具有假定的功能。它在钙结合中的作用表明其参与调节细胞粘附过程的信号通路。已知 GCA 会形成同二聚体,并与 SRI 和 LCP1 相互作用,进一步表明它参与了可以调节细胞功能的蛋白质-蛋白质相互作用。参考文献强调了 GCA 可能参与介导中性粒细胞与纤连蛋白的粘附,并表明其在粘着斑建立中的作用,阐明了其在细胞粘附和信号传导通路中的重要性。

种属

Human

表达系统

E. coli

标签

N-GST

蛋白编号

P28676 (M1-I217)

基因 ID
蛋白结构
N-term
GST
GCA (M1-I217)
Accession # P28676
C-term
同用名
Grancalcin; GCA; GCL
氨基酸序列

MAYPGYGGGFGNFSIQVPGMQMGQPVPETGPAILLDGYSGPAYSDTYSSAGDSVYTYFSAVAGQDGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVACCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTMAI

分子量

Approximately 53 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

性状

无菌粉末.

组分

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 4% Sucrose, 4% Mannitol, 0.02% Tween 80 (w/v), pH 8.0.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

Grancalcin/GCA Protein, Human (GST) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Grancalcin/GCA Protein, Human (GST)
目录号:
HY-P72635
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