Grancalcin/GCA 蛋白, Human (GST)

Grancalcin/GCA protein is a calcium-binding protein that plays a potential role in neutrophil adhesion to fibronectin and focal adhesion formation.As a homodimer, this protein exhibits interactions with SRI and LCP1, suggesting its involvement in molecular pathways related to cell adhesion and cytoskeletal dynamics.Grancalcin/GCA Protein, Human (GST) is the recombinant human-derived Grancalcin/GCA protein, expressed by E.coli , with N-GST labeled tag.

Grancalcin (GCA) 是一种钙结合蛋白，在中性粒细胞粘附纤连蛋白和粘着斑形成中具有假定的功能。它在钙结合中的作用表明其参与调节细胞粘附过程的信号通路。已知 GCA 会形成同二聚体，并与 SRI 和 LCP1 相互作用，进一步表明它参与了可以调节细胞功能的蛋白质-蛋白质相互作用。参考文献强调了 GCA 可能参与介导中性粒细胞与纤连蛋白的粘附，并表明其在粘着斑建立中的作用，阐明了其在细胞粘附和信号传导通路中的重要性。

Human

E. coli

N-GST

P28676 (M1-I217)

25801  [NCBI]

MAYPGYGGGFGNFSIQVPGMQMGQPVPETGPAILLDGYSGPAYSDTYSSAGDSVYTYFSAVAGQDGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVACCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTMAI

Approximately 53 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 4% Sucrose, 4% Mannitol, 0.02% Tween 80 (w/v), pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.