1. 重组蛋白
  2. Enzymes & Regulators
  3. Transferases (EC 2)
  4. GSTP1 蛋白, Human (P.pastoris, His)

GSTP1 蛋白, Human (P.pastoris, His)

目录号: HY-P71740
产品使用指南

GSTP1 蛋白对于将还原型谷胱甘肽与各种疏水性亲电子试剂结合、主动形成 PGA2 和 PGJ2 的谷胱甘肽缀合物至关重要。已记录的研究强调了 GSTP1 在赫泊西林区域异构体合成中的参与,强调了 GSTP1 在处理底物中的多功能性。GSTP1 蛋白, Human (P.pastoris, His) 是重组的 GSTP1 蛋白,由 P. pastoris 表达,带有 N-His 标签。GSTP1 蛋白, Human (P.pastoris, His) 全长 209 个氨基酸,分子量约为 ~25.7 kDa。

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描述

The GSTP1 protein is critical for binding reduced glutathione to a variety of hydrophobic electrophiles, actively forming glutathione conjugates of PGA2 and PGJ2. Documented studies highlight its involvement in hepoxilin regioisomer synthesis, emphasizing the versatility of GSTP1 in processing substrates. GSTP1 Protein, Human (P.pastoris, His) is the recombinant human-derived GSTP1 protein, expressed by P. pastoris , with N-His labeled tag. The total length of GSTP1 Protein, Human (P.pastoris, His) is 209 a.a., with molecular weight of ~25.7 kDa.

研究背景

GSTP1 蛋白在还原型谷胱甘肽与各种外源和内源疏水性亲电子试剂结合的细胞过程中发挥着至关重要的作用。具体而言,正如研究记录的那样,GSTP1 积极参与前列腺素 A2 (PGA2) 和前列腺素 J2 (PGJ2) 谷胱甘肽缀合物的形成。此外,GSTP1 参与新型 hepoxilin 区域异构体的合成,强调了其在处理各种底物方面的多功能性。除了解毒作用外,GSTP1 还通过促进 p25/p35 易位来负向调节 CDK5 活性,成为预防神经退行性变的关键机制。

种属

Human

表达系统

P. pastoris

标签

N-His

蛋白编号

P09211 (P2-Q210)

基因 ID
蛋白结构
N-term
His
GSTP1 (P2-Q210)
Accession # P09211
C-term
同用名
Deafness; Deafness X-linked 7; DFN7; FAEES3; GSTP; Gstp1; GSTP1-1; PI; X linked 7
氨基酸序列

PPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ

分子量

Approximately 25.7 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

GSTP1 Protein, Human (P.pastoris, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
GSTP1 Protein, Human (P.pastoris, His)
目录号:
HY-P71740
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