HEMK2 蛋白, Human (His)

Contrary to the expected interaction, HEMK2 protein did not bind to TRMT112. This unique feature distinguishes HEMK2 from expected protein-protein interactions typically associated with its functional counterparts. HEMK2 Protein, Human (His) is the recombinant human-derived HEMK2 protein, expressed by E. coli , with C-His labeled tag.

根据现有信息，HEMK2 蛋白不与 TRMT112 相互作用。TRMT112 是一种已知与某些甲基转移酶形成复合物并影响其酶活性的蛋白质。HEMK2 和 TRMT112 之间不存在相互作用表明 HEMK2 具有独特的分子特征，与可能与 TRMT112 结合进行功能调节的其他甲基转移酶不同。了解 HEMK2 的特定蛋白质-蛋白质相互作用和调控关联对于揭示其在细胞过程中的作用以及对生物途径的潜在贡献至关重要。需要进一步的研究来阐明与 HEMK2 相关的精确功能和含义，特别是在其独特的相互作用模式的背景下。（参考资料：根据现有资料改编，未注明具体出处）

Measured by its binding ability in a functional ELISA. When Recombinant Human HEMK2 is present at 10 μg/mL, can bind N6AMT1 Polyclonal antibody. The ED₅₀ for this effect is 5.677 ng/mL.

Human

E. coli

C-His

Q9Y5N5-2 (M1-S186)

29104  [NCBI]

MAGENFATPFHGHVGRGAFSDVYEPAEDTFLLLDALEAAAAELAGVEICLEVGSGSGVVSAFLASMIGPQALYMCTDINPEAAACTLETARCNKVHIQPVITDLVGSHGIEAAWAGGRNGREVMDRFFPLVPDLLSPRGLFYLVTIKENNPEEILKIMKTKGLQGTTALSRQAGQETLSVLKFTKS

Approximately 23 kDa

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.