2. 重组蛋白
  3. Cytokines and Growth Factors CAR-T related Proteins CD Antigens Receptor Proteins Enzymes & Regulators
  4. EGF Superfamily ErbB2/HER2 Stem Cell CD Proteins Epithelial cell CD Proteins Endothelial cell CD Proteins Receptor Tyrosine Kinases Protein Tyrosine Kinases
  5. ErbB2/HER2 EGFR/ErbB family
  6. HER2/CD340 蛋白, Rat (HEK293)

HER2/CD340 蛋白, Rat (HEK293)

目录号: HY-P73097
产品使用指南

HER2/CD340 蛋白是受体酪氨酸激酶家族成员之一。HER2/CD340 蛋白 参与 PI3K/Akt 信号通路调控耳蜗核神经干细胞的分化和凋亡。HER2/CD340 蛋白是一种在膀胱癌中过表达的致癌因子，可激活致癌信号通路，从而促进肿瘤细胞的存活/增殖。HER2/CD340 蛋白, Rat (HEK293) 是重组的 HER2/CD340 蛋白，由 HEK293 表达，不带标签。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The HER2/CD340 Protein is a member of the receptor tyrosine kinase family.HER2/CD340 Protein participates in the PI3K/Akt signaling pathway to regulate the differentiation and apoptosis of neural stem cells in the cochlear nucleus.HER2/CD340 Protein is an overexpressed oncogenic factor in bladder cancer that activates the oncogenic signaling pathway, thereby promoting tumor cell survival/proliferation.HER2/CD340 Protein, Rat (HEK293) is the recombinant rat-derived HER2/CD340 protein, expressed by HEK293 , with tag free.
研究背景

ErbB 家族由四个单独的质膜结合受体酪氨酸激酶组成。其中一个是 erbB-2，其他成员是 erbB-1, erbB-3 (神经调节蛋白结合;缺乏激酶结构域) 和 erbB-4。受体酪氨酸蛋白激酶 erbB-2 是一种通常存在于细胞膜上的蛋白，由 ERBB2 基因编码。人蛋白也经常被称为 HER 2 (人表皮生长因子受体 2) 或 CD340 (分化簇340)。HER2 与 Hsp90 蛋白、蛋白酪氨酸激酶和泛素化蛋白有结合活性。ErbB2 通过 PI3K/Akt 通路调控耳蜗核神经干细胞的分化和凋亡。HER2 是一种在膀胱癌中过表达的致癌因子，可激活致癌信号通路，从而促进肿瘤细胞的存活/增殖。
种属

Rat
表达系统

HEK293
标签

Tag Free
蛋白编号

Q8K3F9 (M4-T656)
基因 ID
蛋白结构
N-term
HER2 (M4-T656)
Accession # Q8K3F9
C-term
同用名
Receptor tyrosine-protein kinase erbB-2; MLN 19; CD340; ERBB2; HER2; NEU; NGL
氨基酸序列

MELAAWCRWGFLLALLPPGIAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYVPANASLSFLQDIQEVQGYMLIAHNQVKRVPLQRLRIVRGTQLFEDKYALAVLDNRDPQDNVAASTPGRTPEGLRELQLRSLTEILKGGVLIRGNPQLCYQDMVLWKDVFRKNNQLAPVDIDTNRSRACPPCAPACKDNHCWGESPEDCQILTGTICTSGCARCKGRLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMHNPEGRYTFGASCVTTCPYNYLSTEVGSCTLVCPPNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLRGARAITSDNVQEFDGCKKIFGSLAFLPESFDGDPSSGIAPLRPEQLQVFETLEEITGYLYISAWPDSLRDLSVFQNLRIIRGRILHDGAYSLTLQGLGIHSLGLRSLRELGSGLALIHRNAHLCFVHTVPWDQLFRNPHQALLHSGNRPEEDCGLEGLVCNSLCAHGHCWGPGPTQCVNCSHFLRGQECVEECRVWKGLPREYVSDKRCLPCHPECQPQNSSETCFGSEADQCAACAHYKDSSSCVARCPSGVKPDLSYMPIWKYPDEEGICQPCPINCTHSCVDLDERGCPAEQRASPVT

分子量

95-105 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
HER2/CD340 Protein, Rat (HEK293)
目录号：
HY-P73097
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z