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  4. Histatin-3/HTN3 蛋白, Human

Histatin-3/HTN3 蛋白, Human

目录号: HY-P70298
COA 产品使用指南

Histatin-3/HTN3 蛋白是一种关键的唾液成分，也是牙齿表面牙釉质膜形成的主要前体。除了其结构作用外，histatin-3 还具有抗菌和抗真菌活性，特别是通过其 His3-(20-43)-肽（histatin-5）。Histatin-3/HTN3 蛋白, Human 是重组的 Histatin-3/HTN3 蛋白，由 E. coli 表达，不带标签。Histatin-3/HTN3 蛋白, Human 全长 32 个氨基酸，分子量为 10-12 kDa。

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规格 价格 是否有货 数量
10 μg ￥1800 In-stock
50 μg ￥5000 In-stock
100 μg   询价  

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描述

The Histatin-3/HTN3 protein is a key salivary component and a major precursor in the formation of the enamel film on the tooth surface. In addition to its structural role, histatin-3 also exhibits antibacterial and antifungal activity, particularly through its His3-(20-43)-peptide (histatin-5). Histatin-3/HTN3 Protein, Human is the recombinant human-derived Histatin-3/HTN3 protein, expressed by E. coli , with tag free. The total length of Histatin-3/HTN3 Protein, Human is 32 a.a., with molecular weight of 10-12 kDa.
研究背景

Histatin-3/HTN3 蛋白是唾液蛋白的重要组成部分，作为牙齿表面保护性蛋白质结构（称为牙釉质薄膜）形成的主要前体，发挥着至关重要的作用。除了其结构功能外，histatin-3 还表现出显着的抗菌和抗真菌活性，其 His3-(20-43)-肽 (histatin-5) 对白色念珠菌和新型念珠菌具有特殊功效，同时还抑制 Lys-gingipain 和来自牙龈卟啉单胞菌的精氨酸牙龈蛋白酶 (rgpB)。该肽还充当金属蛋白酶 MMP2 和 MMP9 的有效抑制剂。有趣的是，His3-(20-43)-肽以同二聚体的形式存在。Histatin-3 及其 His3-(20-43)-肽对应物与酵母 SSA1 和 SSA2 蛋白相互作用，强调其在宿主防御和口腔健康中的多方面作用。
种属

Human
表达系统

E. coli
标签

Tag Free
蛋白编号

P15516 (D20-N51)
基因 ID
蛋白结构
N-term
HTN3 (D20-N51)
Accession # P15516
C-term
同用名
rHuHistatin-3/HTN3; Histatin-3; Basic histidine-rich protein; Histidine-rich protein 3; PB; HTN3.
氨基酸序列

DSHAKRHHGYKRKFHEKHHSHRGYRSNYLYDN

分子量

10-12 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
性状

溶液.
组分

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
内毒素含量

<1 EU/μg, determined by LAL method.
保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
运输条件

Shipping with dry ice.
文件资料

COA (208 KB)

产品使用指南 (1213 KB)

Histatin-3/HTN3 Protein, Human 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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