2. 重组蛋白
  3. Biotinylated Proteins Others
  4. HLA-A*0101 MAGE-A3 Complex Tetramer 蛋白, Human (EVDPIGHLY, HEK293, His-Avi)

HLA-A*0101 MAGE-A3 Complex Tetramer 蛋白, Human (EVDPIGHLY, HEK293, His-Avi)

目录号: HY-P700936
产品使用指南

HLA-A*0201 MAGE-A3 复合蛋白是主要组织相容性复合体 (MHC) I 类家族的重要成员，可促进对乙型肝炎病毒 (HBV) 的免疫识别和反应。通过将 HBV 衍生肽呈递给细胞毒性 T 细胞，它有助于 MHC I 类途径内的抗病毒防御机制，强调其在针对感染或异常细胞的适应性免疫和免疫系统监视中的关键作用。HLA-A*0101 MAGE-A3 Complex Tetramer 蛋白, Human (EVDPIGHLY, HEK293, His-Avi) 是重组的蛋白二聚体复合物，包含 HLA-A*0101 和 B2M/Beta-2-microglobulin Protein，由 HEK293 表达，带有 C-Avi, C-His 标签。 和 EVDPIGHLY Y:Y。HLA-A*0101 MAGE-A3 Complex Tetramer 蛋白, Human (EVDPIGHLY, HEK293, His-Avi) ，分子量为 260-265 kDa。

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描述

HLA-A*0201 MAGE-A3 Complex Protein, a vital member of the major histocompatibility complex (MHC) class I family, facilitates immune recognition and response to hepatitis B virus (HBV). By presenting HBV-derived peptides to cytotoxic T cells, it contributes to antiviral defense mechanisms within the MHC class I pathway, emphasizing its pivotal role in adaptive immunity and immune system surveillance against infected or aberrant cells. HLA-A*0101 MAGE-A3 Complex Tetramer Protein, Human (EVDPIGHLY, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*0101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and EVDPIGHLY peptide. HLA-A*0101 MAGE-A3 Complex Tetramer Protein, Human (EVDPIGHLY, HEK293, His-Avi), has molecular weight of 260-265 kDa.
研究背景

HLA-A*0201 HBV 复合物四聚体蛋白是主要组织相容性复合物 (MHC) I 类家族的成员，是免疫系统识别和对外来抗原做出反应的能力的组成部分。作为该家族的一部分，该蛋白参与将乙型肝炎病毒 (HBV) 衍生的病毒肽呈递给细胞毒性 T 细胞，从而有助于针对 HBV 感染的免疫反应。该蛋白参与的 MHC I 类途径在免疫系统监视和消除受感染或异常细胞中发挥着至关重要的作用。HLA-A*0201 与 HBV 衍生肽的特异性相互作用强调了其在适应性免疫中的重要性，突出了其在抗病毒防御机制中的作用。
种属

Human
表达系统

HEK293
标签

C-Avi;C-His
蛋白编号

Q5SUL5 (G25-T305)&P61769 (I21-M119)&EVDPIGHLY
基因 ID

3105&567
同用名
MAGE family member A3; HIP8; HYPD; CT1.3; MAGE3; MAGEA6
分子量

260-265 kDa under Non reducing (N) condi
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

HLA-A*0101 MAGE-A3 Complex Tetramer Protein, Human (EVDPIGHLY, HEK293, His-Avi) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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