IL-13R alpha 2 蛋白, Canine (HEK293, His)

The IL-13R α2 protein is a receptor for interleukin 13 (IL-13), a signaling molecule involved in immune responses. By binding to IL-13, the IL-13R α2 protein is thought to regulate IL-13-mediated immune responses and may serve as a therapeutic target for diseases associated with IL-13 dysregulation. IL-13R alpha 2 Protein, Canine (HEK293, His) is the recombinant canine-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-His labeled tag. The total length of IL-13R alpha 2 Protein, Canine (HEK293, His) is 317 a.a., with molecular weight of 39-46 kDa.

IL-13R α2 蛋白是白细胞介素 13 (IL-13) 的受体，白细胞介素 13 是一种参与免疫反应的信号分子。通过与 IL-13 结合，IL-13R α2 蛋白被认为可以调节 IL-13 介导的免疫反应，并有可能作为与 IL-13 失调相关疾病的治疗靶点。

Measured by its ability to inhibit IL13-dependent proliferation of TF-1 human erythroleukemic cells. The ED₅₀ for this effect is typically 0.01287 μg/mL, corresponding to a specific activity is 7.770×10⁴ U/mg.

Canine

HEK293

C-His

Q95LF0 (S22-T338)

403622  [NCBI]

SMLSNAEIKVNPPQDFEIVDPGYLGYLSLQWQPPLFPDNFKECTIEYELKYRNIDSENWKTIITKNLHYKDGFDLNKGIEAKINTLLPAQCTNGSEVRSSWAETTYWTSPQGNRETKIQDMDCVYYNWQYLVCSWKPGMGVHFDTNYQLFYWYEGLDHSAECTDYIKVNGKNMGCRFPYLESSDYKDFYICVNGSSESQPIRPSYFIFQLQNIVKPMPPDYLSLTVKNSEEINLKWNMPKGPIPAKCFIYEIEFTEDGTTWVTTTVENEIQITRTSNESQKLCFLVRSKVNIYCSDDGIWSEWSDEQCWKGDIWKET

Approximately 38-50 kDa due to glycosylation

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.